Submissions from 2022
Federated learning enables big data for rare cancer boundary detection, Sarthak Pati, Pamela LaMontagne, Daniel Marcus, and et al.
Impact of international travel and diarrhea on gut microbiome and resistome dynamics, Manish Boolchandani, Kevin S Blake, Drake H Tilley, Miguel M Cabada, Drew J Schwartz, Sanket Patel, Maria Luisa Morales, Rina Meza, Giselle Soto, Sandra D Isidean, Chad K Porter, Mark P Simons, and Gautam Dantas
The polyamine spermine potentiates the propagation of negatively charged molecules through the astrocytic syncytium, Jan Benedikt, Christian J Malpica-Nieves, Yomarie Rivera, Miguel Méndez-González, Colin G Nichols, Rüdiger W Veh, Misty J Eaton, and Serguei N Skatchkov
TikTok Tourette's: Are we witnessing a rise in functional tic-like behavior driven by adolescent social media use?, Jessica Frey, Kevin J Black, and Irene A Malaty
Discrimination of normal and cancerous human skin tissues based on laser-induced spectral shift fluorescence microscopy, A Niazi, A Ehtesham, and et al.
Distinct tumor necrosis factor alpha receptors dictate stem cell fitness versus lineage output in Dnmt3a-mutant clonal hematopoiesis, Jennifer M SanMiguel, Elizabeth Eudy, Matthew A Loberg, Kira A Young, Jayna J Mistry, Kristina D Mujica, Logan S Schwartz, Timothy M Stearns, Grant A Challen, and Jennifer J Trowbridge
Equity implications of hospital penalties during 4 years of the Comprehensive Care for Joint Replacement model, 2016 to 2019, Sukruth A Shashikumar, Andrew M Ryan, and Karen E Joynt Maddox
Genome-edited zebrafish model of ABCC8 loss-of-function disease, Jennifer M Ikle, Robert C Tryon, Soma S Singareddy, Nathaniel W York, Maria S Remedi, and Colin G Nichols
Hyperkalemia and electrocardiogram manifestations in end-stage renal disease, Zubaid Rafique, Bryan Hoang, Heba Mesbah, Ryan Pappal, Frank W Peacock, Raul Juarez-Vela, Lukasz Szarpak, and Dick C Kuo
Identification of novel antifungal skeleton of hydroxyethyl naphthalimides with synergistic potential for chemical and dynamic treatments, Pengli Zhang, Vijai Kumar Reddy Tangadanchu, and Chenghe Zhou
A novel, likely pathogenic variant in UBTF-related neurodegeneration with brain atrophy is associated with a severe divergent neurodevelopmental phenotype, Rory J Tinker, Tiffany Guess, David C Rinker, Jonathan H Sheehan, Daniel Lubarsky, Binu Porath, Mackenzie Mosera, Ping Mayo, Emily Solem, Laura A Lee, Asha Sharam, and Jennifer Brault
Approaches to healthcare personnel exemption requests from coronavirus disease 2019 (COVID-19) vaccination: Results of a national survey, Thomas R Talbot, Susan E Beekmann, Hilary M Babcock, and Philip M Polgreen
A SARM1-mitochondrial feedback loop drives neuropathogenesis in a Charcot-Marie-Tooth disease type 2A rat model, Yurie Sato-Yamada, Amy Strickland, Yo Sasaki, Joseph Bloom, Aaron DiAntonio, and Jeffrey Milbrandt
Association of leukocyte telomere length with perceived physical fatigability, Rain Katz, Emma L Gay, Allison L Kuipers, Joseph H Lee, Lawrence S Honig, Kaare Christensen, Mary F Feitosa, Mary K Wojczynski, Nancy W Glynn, and LLFS Research Group
Benefits of early treatment with natalizumab: A real-world study, Daniel Ontaneda, Ellen M Mowry, Scott D Newsome, Robert T Naismith, Jacqueline Nicholas, Elizabeth Fisher, Carl de Moor, Justin Bohn, Pei-Ran Ho, Al Sandrock, Richard Rudick, and James R Williams
Bone metabolism and incretin hormones following glucose ingestion in young adults with pancreatic insufficient cystic fibrosis, Wang Shin Lei, Marissa J Kilberg, Babette S Zemel, Ronald C Rubenstein, Clea Harris, Saba Sheikh, Andrea Kelly, and Joseph M Kindler
Changes in racial equity associated with participation in the Bundled Payments for Care Improvement Advanced Program, Gmerice Hammond, E John Orav, Jie Zheng, Arnold M Epstein, and Karen E Joynt Maddox
Chronic cochlear implantation with and without electric stimulation in a mouse model induces robust cochlear influx of CX3CR1+/GFP macrophages, Alexander D Claussen, René Vielman Quevedo, Jonathon R Kirk, Timon Higgins, Brian Mostaert, Muhammad Taifur Rahman, Jacob Oleson, Reyna Hernandez, Keiko Hirose, and Marlan R Hansen
Circulating tumour DNA characterisation of invasive lobular carcinoma in patients with metastatic breast cancer, Andrew A Davis, Katherine Clifton, Whitney L. Hensing, Nusayba A. Bagegni, Foluso O. Ademuyiwa, Ron Bose, Cynthia X. Ma, and et al.
Cisplatin exposure acutely disrupts mitochondrial bioenergetics in the zebrafish lateral-line organ, David S Lee, Angela Schrader, Mark Warchol, and Lavinia Sheets
Cognition and the single neuron: How cell types construct the dynamic computations of frontal cortex, Amelia J Christensen, Torben Ott, and Adam Kepecs
Comparing antigenaemia- and microfilaraemia as criteria for stopping decisions in lymphatic filariasis elimination programmes in Africa, Wilma A. Stolk, Luc E. Coffeng, Fatorma K. Bolay, Obiora A. Eneanya, Peter U. Fischer, T. Déirdre Hollingsworth, Benjamin G. Koudou, Aboulaye Méité, Edwin Michael, Joaquin M. Prada, Rocio M. Caja Rivera, Swarnali Sharma, Panayiota Touloupou, Gary J. Weil, and Sake J. de Vlas
Derivation and validation of a clinical prediction rule for upper limb functional outcomes after traumatic cervical spinal cord injury, Saad Javeed, Jacob K Greenberg, Justin K Zhang, Christopher F Dibble, Jawad M Khalifeh, Ying Liu, Thomas J Wilson, Lynda J Yang, Yikyung Park, and Wilson Z Ray
Differential roles of Aβ42/40, p-tau231 and p-tau217 for Alzheimer's trial selection and disease monitoring, Nicholas J Ashton, Yan Li, Randall J Bateman, and et al.
Diptoindonesin G is a middle domain HSP90 modulator for cancer treatment, Kristine Donahue, Haibo Xie, Miyang Li, Ang Gao, Min Ma, Yidan Wang, Rose Tipton, Nicole Semanik, Tina Primeau, Shunqiang Li, Lingjun Li, Weiping Tang, and Wei Xu
First-generation and continuing-generation college graduates' application, acceptance, and matriculation to U.S. medical schools: A national cohort study, Hyacinth R C Mason, Ashar Ata, Mytien Nguyen, Sunny Nakae, Devasmita Chakraverty, Branden Eggan, Sarah Martinez, and Donna B Jeffe
G protein gamma subunit, a hidden master regulator of GPCR signaling, Dinesh Kankanamge, Mithila Tennakoon, Ajith Karunarathne, and N Gautam
Gunshot wound to the spine with delayed radiculopathy: A case report, Kunj Patel, Rachita Navara, Faizal Ouedraogo, Ronald Joel, and Brock Bowman
Identification of patients with ovarian cancer experiencing the highest benefit from bevacizumab in the first-line setting on the basis of their tumor-intrinsic chemosensitivity (KELIM): The GOG-0218 validation study, Benoit You, David Mutch, and et al.
Impact of aortic valve effective height following valve-sparing root replacement on postoperative insufficiency and reoperation, Puja Kachroo, Meghan O Kelly, Nadia H Bakir, Catherine Cooper, Alan C Braverman, Nicholas T Kouchoukos, and Marc R Moon
Implementing educational and systems-level changes to improve cancer screening rates among state employees in Missouri, Misty A Phillips, Sarah Chavez, Maggie Grotefendt, Xarria Lewis, Melanie Gowdy, Jane A McElroy, Jean S Wang, and Sandra Hentges
'I need time to start antiretroviral therapy': Understanding reasons for delayed ART initiation among people diagnosed with HIV in Lusaka, Zambia, Chanda Mwamba, Laura K Beres, Stephanie M Topp, Njekwa Mukamba, Sandra Simbeza, Kombatende Sikombe, Aaloke Mody, Elvin Geng, Charles B Holmes, Caitlin E Kennedy, Izukanji Sikazwe, Julie A Denison, and Carolyn Bolton Moore
Listeria motility increases the efficiency of epithelial invasion during intestinal infection, Inge M. N. Wortel, Seonyoung Kim, Annie Y. Liu, Enid C. Ibarra, and Mark J. Miller
Macrophage depletion blocks congenital SARM1-dependent neuropathy, Caitlin B Dingwall, Amy Strickland, Sabrina W Yum, Aldrin Ky Yim, Jian Zhu, Peter L. Wang, Yurie Yamada, Robert E. Schmidt, Yo Sasaki, A. Joseph Bloom, Aaron DiAntonio, and Jeffrey Milbrandt
Mild hypoxic-ischemic encephalopathy (HIE): Timing and pattern of MRI brain injury, Yi Li, Jessica L Wisnowski, Lina Chalak, Amit M Mathur, Robert C McKinstry, Genesis Licona, Dennis E Mayock, Taeun Chang, Krisa P Van Meurs, Tai-Wei Wu, Kaashif A Ahmad, Marie-Coralie Cornet, Rakesh Rao, Aaron Scheffler, and Yvonne W Wu
Mouse tissue harvest-induced hypoxia rapidly alters the in vivo metabolome, between-genotype metabolite level differences, and 13C-tracing enrichments, Adam J Rauckhorst, Nicholas Borcherding, Daniel J Pape, Alora S Kraus, Diego A Scerbo, and Eric B Taylor
OpenSep: A generalizable open source pipeline for SOFA score calculation and Sepsis-3 classification, Mackenzie R Hofford, Sean C Yu, Alistair E W Johnson, Albert M Lai, Philip R O Payne, and Andrew P Michelson
Public interest in hyaluronic acid injections for knee osteoarthritis in the United States and Europe: An international Google Trends analysis, Samuel A Cohen, Robert H Brophy, Antonia F Chen, Karl C Roberts, Robert H Quinn, and Kevin G Shea
Racial and ethnic differences in internal medicine residency assessments, Dowin Boatright, Nientara Anderson, Jung G Kim, Eric S Holmboe, William A McDade, Tonya Fancher, Cary P Gross, Sarwat Chaudhry, Mytien Nguyen, Max Jordan Nguemeni Tiako, Eve Colson, Yunshan Xu, Fangyong Li, James D Dziura, and Somnath Saha
Racial and ethnic disparities in access to minimally invasive mitral valve surgery, Laurent G Glance, Karen E Joynt Maddox, Michael Mazzefi, Peter W Knight, Michael P Eaton, Changyong Feng, Miklos D Kertai, James Albernathy, Isaac Y Wu, Julie A Wyrobek, Marisa Cevasco, Nimesh Desai, and Andrew W Dick
Ten simple rules and a template for creating workflows-as-applications, Michael J. Roach, N. Tessa Pierce-Ward, Radoslaw Suchecki, Vijini Mallawaarachchi, Bhavya Papudeshi, Scott A. Handley, C. Titus Brown, Nathan S. Watson-Haigh, and Robert A. Edwards
The clinical landscape of cell-free DNA alterations in 1671 patients with advanced biliary tract cancer, J E Berchuck, B Tan, and et al.
The clinical spectrum of SMA-PME and in vitro normalization of its cellular ceramide profile, Michelle M Lee, Toni S Pearson, and et al.
The genetic risk factor CEL-HYB1 causes proteotoxicity and chronic pancreatitis in mice, Karianne Fjeld, Steven J Wilhelm, Jianguo Lin, Xunjun Xiao, Mark E Lowe, and et al.
The zona incerta in control of novelty seeking and investigation across species, Ilya E Monosov, Takaya Ogasawara, Suzanne N Haber, J Alexander Heimel, and Mehran Ahmadlou
Transferability of Alzheimer disease polygenic risk score across populations and its association with Alzheimer disease-related phenotypes, Sang-Hyuk Jung, Carlos Cruchaga, and et al.
Ubiquitin variants potently inhibit SARS-CoV-2 PLpro and viral replication via a novel site distal to the protease active site, Vera J. E. van Vliet, Nitin Sharma, Safder S. Ganaie, Gaya K. Amarasinghe, and et al
Vascular endothelial-cadherin as a marker of endothelial injury in preclinical Alzheimer disease, Rawan Tarawneh, Rachel S Kasper, Jessie Sanford, Chia-Ling Phuah, Jason Hassenstab, and Carlos Cruchaga
Water T2 could predict functional decline in patients with dysferlinopathy, Ursula Moore, Alan Pestronk, and et al.
Wellness and coping of physicians who worked in ICUs during the pandemic: A multicenter cross-sectional North American survey, Karen E. A. Burns, Rachel K. McDonald, and et al.
Whole-genome and long-read sequencing identify a novel mechanism in RFC1 resulting in CANVAS syndrome, Katherine Abell King, Daniel J. Wegner, Robert C. Bucelli, Jessica Shapiro, Alexander J. Paul, Patricia I. Dickson, Jennifer A. Wambach, and Undiagnosed Disease Network
X-linked hypophosphatemia caused by the prevailing North American PHEX variant c.*231A>G; exon 13–15 duplication is often misdiagnosed as ankylosing spondylitis and manifests in both men and women, Kathryn McCrystal Dahir, Margo Black, Gary S Gottesman, Erik A Imel, Steven Mumm, Cindy M Nichols, and Michael P Whyte
Immune checkpoint inhibitor therapy and outcomes from SARS-CoV-2 infection in patients with cancer: A joint analysis of OnCovid and ESMO-CoCARE registries, Alessio Cortellini, Gino M Dettorre, and et al.
Clinical management of supratentorial non-skull case meningiomas, Adefisayo Adekanmbi, Mark W Youngblood, Constantine L Karras, Ephraim A Oyetunji, John Kalapurakal, Craig M Horbinski, Hinda Najem, Virginia B Hill, James P Chandler, Amy B Heimberger, Stephen T Magill, and Rimas V Lukas
Single-cell RNA sequencing identifies a paracrine interaction that may drive oncogenic notch signaling in human adenoid cystic carcinoma, Anuraag S. Parikh, Avishai Wizel, Daniel Davis, Armida Lefranc-Torres, Alejandro I. Rodarte-Rascon, Lauren E. Miller, Kevin S. Emerick, Mark A. Varvares, Daniel G. Deschler, William C. Faquin, Jon C. Aster, Derrick T. Lin, Bradley E. Bernstein, Yotam Drier, and Sidharth V. Puram
Comprehensive transcriptomic analysis of VISTA in acute myeloid leukemia: Insights into its prognostic value, Simona Pagliuca, Carmelo Gurnari, Keman Zhang, Tariq Kewan, Waled Bahaj, Minako Mori, Ishani Nautiyal, Marie Thérèse Rubio, Francesca Ferraro, Jaroslaw P Maciejewski, Li Wang, and Valeria Visconte
Determining epigenetic memory in kidney proximal tubule cell derived induced pluripotent stem cells using a quadruple transgenic reprogrammable mouse, Gabriel Khelifi, Theresa Chow, Jennifer Whiteley, Victoire Fort, Benjamin D Humphreys, Samer M I Hussein, and Ian M Rogers
Immune phenotypes that are associated with subsequent COVID-19 severity inferred from post-recovery samples, Thomas Liechti, Yaser Iftikhar, Massimo Mangino, Margaret Beddall, Charles W Goss, Jane A O'Halloran, Philip A Mudd, and Mario Roederer
CSF tau microtubule-binding region identifies pathological changes in primary tauopathies, Kanta Horie, Nicolas R Barthélemy, Yingxin He, Albert A Davis, Celeste M Karch, Richard J Perrin, Rama K Koppisetti, Faris Shaikh, Nupur Ghoshal, Randall J Bateman, Chihiro Sato, and et al.
MaHPIC malaria systems biology data from Plasmodium cynomolgi sporozoite longitudinal infections in macaques, Jeremy D DeBarry, Xuntian Jiang, Daniel S Ory, and et al.
Wakeful rest benefits recall, but not recognition, of incidentally encoded memory stimuli in younger and older adults, Peter R Millar and David A Balota
Cortex-wide response mode of VIP-expressing inhibitory neurons by reward and punishment, Zoltán Szadai, Hyun-Jae Pi, Quentin Chevy, Katalin Ócsai, Dinu F Albeanu, Balázs Chiovini, Gergely Szalay, Gergely Katona, Adam Kepecs, and Balázs Rózsa
Muscle-specific ablation of glucose transporter 1 (GLUT1) does not impair basal or overload-stimulated skeletal muscle glucose uptake, Shawna L McMillin, Parker L Evans, William M Taylor, Luke A Weyrauch, Tyler J Sermersheim, Steven S Welc, Monique R Heitmeier, Richard C Hresko, Paul W Hruz, Francoise Koumanov, Geoffrey D Holman, E Dale Abel, and Carol A Witczak
Chatbot-delivered cognitive behavioral therapy in adolescents with depression and anxiety during the COVID-19 pandemic: Feasibility and acceptability study, Ginger Nicol, Ruoyun Wang, Sharon Graham, Sherry Dodd, and Jane Garbutt
Dose-dependent von Willebrand Factor inhibition by aptamer BB-031 correlates with thrombolysis in a microfluidic model of arterial occlusion, Susan M Shea, Kimberly A Thomas, Rassam M G Rassam, Emily P Mihalko, Christina Daniel, Bruce A Sullenger, Philip C Spinella, and Shahid M Nimjee
Myostatin is a negative regulator of adult neurogenesis after spinal cord injury in zebrafish, Vishnu Muraleedharan Saraswathy, Lili Zhou, Anthony R McAdow, Brooke Burris, Deepika Dogra, Sven Reischauer, and Mayssa H Mokalled
EEG-based grading of Immune Effector Cell-Associated Neurotoxicity Syndrome, Daniel K Jones, Fábio A Nascimento, and et al.
Let's talk about antibiotics: A randomised trial of two interventions to reduce antibiotic misuse, Kathy Goggin, Emily A. Hurley, Brian R. Lee, Andrea Bradley-Ewing, Carey Bickford, Kimberly Pina, Evelyn Donis de Miranda, David Yu, Kirsten Weltmer, Sebastian Linnemayr, Christopher C. Butler, Jason G. Newland, and Angela L Myers
Multi-method investigation of factors influencing amyloid onset and impairment in three cohorts, Tobey J Betthauser, Dean F Wong, and et al.
Structural basis of synthetic agonist activation of the nuclear receptor REV-ERB, Meghan H Murray, Aurore Cecile Valfort, Thomas Koelblen, Céline Ronin, Fabrice Ciesielski, Arindam Chatterjee, Giri Babu Veerakanellore, Bahaa Elgendy, John K Walker, Lamees Hegazy, and Thomas P Burris
An mTORC1 to HRI signaling axis promotes cytotoxicity of proteasome inhibitors in multiple myeloma, Odai Darawshi, Barbara Muz, and et al.
De novo serine biosynthesis from glucose predicts sex-specific response to antifolates in non-small cell lung cancer cell lines, Jasmin Sponagel, Siddhartha Devarakonda, Joshua B Rubin, Jingqin Luo, and Joseph E Ippolito
Evaluation of cisplatin-induced pathology in the larval zebrafish lateral line, David S Lee, Angela Schrader, Emily Bell, Mark E Warchol, and Lavinia Sheets
Open-channel structure of a pentameric ligand-gated ion channel reveals a mechanism of leaflet-specific phospholipid modulation, John T Petroff 2nd, Noah M Dietzen, Ezry Santiago-McRae, Brett Deng, Maya S Washington, Lawrence J Chen, K Trent Moreland, Zengqin Deng, Michael Rau, James A J Fitzpatrick, Peng Yuan, Thomas T Joseph, Jérôme Hénin, Grace Brannigan, and Wayland W L Cheng
Collegiate wrestler with a bicuspid aortic valve and aortic dilation, Rahul Chhana, Christopher Rymer, Mahesh Vidula, Kristopher Fayock, Helene Glassberg, Chris Kusmiesz, Mustafa Husaini, Sanjay Sivalokanathan, Neel Chokshi, and Sheela Krishnan
SLc7a8 is a key amino acids supplier for the metabolic programs that sustain homeostasis and activation of type 2 innate lymphoid cells, Santosh K Panda, Do-Hyun Kim, Pritesh Desai, Patrick F Rodrigues, Raki Sudan, Susan Gilfillan, Marina Cella, Steven J Van Dyken, and Marco Colonna
The quality of energy- and macronutrient-balanced diets regulates host susceptibility to influenza in mice, Taylor A Cootes, Nayan D Bhattacharyya, Susie S Y Huang, Lina Daniel, Kim S Bell-Anderson, Sebastian A Stifter, Tracy Chew, Samantha M Solon-Biet, Luis R Saraiva, Yi Cai, Xinchun Chen, Stephen J Simpson, and Carl G Feng
β-amyloid PET harmonisation across longitudinal studies: Application to AIBL, ADNI and OASIS3, Pierrick Bourgeat, Manu Goyal, Pamela LaMontagne, John C Morris, and et al.
Inhibiting ACK1-mediated phosphorylation of C-terminal Src kinase counteracts prostate cancer immune checkpoint blockade resistance, Dhivya Sridaran, Surbhi Chouhan, Kiran Mahajan, Arun Renganathan, Cody Weimholt, Shambhavi Bhagwat, Melissa Reimers, Eric H Kim, Manish K Thakur, Muhammad A Saeed, Russell K Pachynski, Markus A Seeliger, W Todd Miller, Felix Y Feng, and Nupam P Mahajan
Molecular subclasses of clear cell ovarian carcinoma and their impact on disease behavior and outcomes, Kelly L Bolton, Irenaeus C C Chan, Brian J Wiley, and et al.
Race and gender-based perceptions of older septuagenarian adults, Forest Melton, Kelly Palmer, Sade Solola, Luis Luy, Kathryn Herrera-Theut, Leanne Zabala, Shannon M Knapp, Ryan Yee, Erika Yee, Elizabeth Calhoun, Megan C Thomas Hebdon, Natalie Pool, Nancy Sweitzer, and Khadijah Breathett
Enterotoxigenic Escherichia coli heat-labile toxin drives enteropathic changes in small intestinal epithelia, Alaullah Sheikh, Brunda Tumala, Tim J Vickers, John C Martin, Bruce A Rosa, Subrata Sabui, Supratim Basu, Rita D Simoes, Makedonka Mitreva, Chad Storer, Erik Tyksen, Richard D Head, Wandy Beatty, Hamid M Said, and James M Fleckenstein
Structural basis for mechanotransduction in a potassium-dependent mechanosensitive ion channel, Jonathan Mount, Grigory Maksaev, Brock T Summers, James A J Fitzpatrick, and Peng Yuan
The SOD1-mediated ALS phenotype shows a decoupling between age of symptom onset and disease duration, Sarah Opie-Martin, Jennifer Jockel-Balsarotti, Taha Bali, Wade Self, Timothy Miller, and et al.
Collective genomic segments with differential pleiotropic patterns between cognitive dimensions and psychopathology, Max Lam, Chia-Yen Chen, W David Hill, Charley Xia, Ruoyu Tian, Daniel F Levey, Joel Gelernter, Murray B Stein, Alexander S Hatoum, Hailiang Huang, Anil K Malhotra, Heiko Runz, Tian Ge, and Todd Lencz
Imprinted antibody responses against SARS-CoV-2 Omicron sublineages, Young-Jun Park, Zhuoming Liu, Javier Janer, Sean P J Whelan, Herbert W Virgin, and et al.
Sex differences in brain tumor glutamine metabolism reveal sex-specific vulnerabilities to treatment, Jasmin Sponagel, Jill K Jones, Cheryl Frankfater, Shanshan Zhang, Olivia Tung, Kevin Cho, Kelsey L Tinkum, Hannah Gass, Elena Nunez, Gary J Patti, Jingqin Luo, Joshua B Rubin, Joseph E Ippolito, and et al.
Acute and postacute sequelae associated with SARS-CoV-2 reinfection, Benjamin Bowe, Yan Xie, and Ziyad Al-Aly
FDG-PET/MRI for nonoperative management of rectal cancer: A prospective pilot study, Semra Ince, Malak Itani, Lauren E Henke, Radhika K Smith, Paul E Wise, Matthew G Mutch, Sean C Glasgow, Matthew L Silviera, Katrina S Pedersen, Steven R Hunt, Hyun Kim, and Tyler J Fraum
A human STAT3 gain-of-function variant confers T cell dysregulation without predominant Treg dysfunction in mice, Erica G Schmitt, Kelsey A Toth, Samuel I Risma, Ana Kolicheski, Nermina Saucier, Rafael J. Feliciano Berríos, Zev J. Greenberg, Jennifer W. Leiding, Jack J. Bleesing, Akaluck Thatayatikom, Laura G. Schuettpelz, John R. Edwards, Tiphanie P. Vogel, and Megan A Cooper
Combination of common mtDNA variants results in mitochondrial dysfunction and a connective tissue dysregulation, Patrick M Schaefer, Benjamin A Garcia, and et al.
Genetic addiction risk severity assessment identifies polymorphic reward genes as antecedents to reward deficiency syndrome (RDS) hypodopaminergia's effect on addictive and non-addictive behaviors in a nuclear family, Catherine A Dennen, Kenneth Blum, Abdalla Bowirrat, Panayotis K Thanos, Igor Elman, Mauro Ceccanti, Rajendra D Badgaiyan, Thomas McLaughlin, Ashim Gupta, Anish Bajaj, David Baron, B William Downs, Debasis Bagchi, and Mark S Gold
Ornithine decarboxylase supports ILC3 responses in infectious and autoimmune colitis through positive regulation of IL-22 transcription, Vincent Peng, Siyan Cao, Tihana Trsan, Jennifer K Bando, Julian Avila-Pacheco, John L Cleveland, Clary Clish, Ramnik J Xavier, and Marco Colonna
The evolution, current indications and outcomes of cementless total knee arthroplasty, Maria T Schwabe and Charles P Hannon
Tuft-cell-intrinsic and -extrinsic mediators of norovirus tropism regulate viral immunity, Madison S Strine, Mia Madel Alfajaro, Vincent R Graziano, Jaewon Song, Leon L Hsieh, Ryan Hill, Jun Guo, Kelli L VanDussen, Robert C Orchard, Megan T Baldridge, Sanghyun Lee, and Craig B Wilen
High-throughput analysis of tissue microarrays using automated desorption electrospray ionization mass spectrometry, Nicolás M Morato, Hannah Marie Brown, Diogo Garcia, Erik H Middlebrooks, Mark Jentoft, Kaisorn Chaichana, Alfredo Quiñones-Hinojosa, and R Graham Cooks
Socioeconomic status and modification of atherosclerotic cardiovascular disease risk prediction: Epidemiological analysis using data from the Atherosclerosis Risk In Communities study, Kamal Henderson, Brystana Kaufman, Jason S. Rotter, Sally Stearns, Carla A A Sueta, Randi Foraker, P Michael Ho, and Patricia P Chang
Oxidative stress-induced cellular senescence in aging retina and age-related macular degeneration, Ryo Terao, Tazbir Ahmed, Ayana Suzumura, and Hiroko Terasaki
Preventive behaviors and information sources during COVID-19 pandemic: A cross-sectional study in Japan, Manae Uchibori, Cyrus Ghaznavi, Michio Murakami, Akifumi Eguchi, Hiroyuki Kunishima, Satoshi Kaneko, Keiko Maruyama-Sakurai, Hiroaki Miyata, and Shuhei Nomura
Single-cell multiomics identifies clinically relevant mesenchymal stem-like cells and key regulators for MPNST malignancy, Lai Man Natalie Wu, Joshua Rubin, and et al.
