Submissions from 2024
Synergizing deep learning-enabled preprocessing and human-AI integration for efficient automatic ground truth generation, Christopher Collazo, Ian Vargas, Brendon Cara, Carla J Weinheimer, Ryan P Grabau, Dmitry Goldgof, Lawrence Hall, Samuel A Wickline, and Hua Pan
Tailoring FXR modulators for intestinal specificity: Recent progress and insights, Amanda Morrison and Bahaa Elgendy
Disordered clock protein interactions and charge blocks turn an hourglass into a persistent circadian oscillator, Meaghan S Jankowski, Daniel Griffith, Divya G Shastry, Jacqueline F Pelham, Garrett M Ginell, Joshua Thomas, Pankaj Karande, Alex S Holehouse, and Jennifer M Hurley
Type 2 cannabinoid receptor expression on microglial cells regulates neuroinflammation during graft-versus-host disease, Alison Moe, Aditya Rayasam, Garrett Sauber, Ravi K. Shah, Ashley Doherty, Cheng-Yin Yuan, Aniko Szabo, Bob M. Moore II, Marco Colonna, Weiguo Cui, Julian Romero, Anthony E. Zamora, Cecilia J Hillard, and William R. Drobyski
An update on implant-associated malignancies and their biocompatibility, Grace C Keane Tahmaseb, Alexandra M Keane, Jose A Foppiani, and Terence M Myckatyn
MYADM binds human parechovirus 1 and is essential for viral entry, Wenjie Qiao, Christopher M Richards, Youlim Kim, James R Zengel, Siyuan Ding, Harry B Greenberg, and Jan E Carette
Patlak slope versus standardized uptake value image quality in an oncologic PET/CT population: A prospective cross-sectional study, Semra Ince, Richard Laforest, Malak Itani, Vikas Prasad, Saeed Ashrafinia, Anne M Smith, Richard L Wahl, and Tyler J Fraum
Amino terminal acetylation of HOXB13 regulates the DNA damage response in prostate cancer, Duy T Nguyen, Urvashi Mahajan, Duminduni Hewa Angappulige, Aashna Doshi, Nupam P Mahajan, and Kiran Mahajan
Large-scale annotated dataset for cochlear hair cell detection and classification, Christopher J Buswinka, Jinkyung Kim, Anthony J Ricci, Mark A Rutherford, and et al.
An approach to identify gene-environment interactions and reveal new biological insight in complex traits, Xiaofeng Zhu, Yihe Yang, Noah Lorincz-Comi, Gen Li, Amy R Bentley, Paul S de Vries, Michael Brown, Alanna C Morrison, Charles N Rotimi, W James Gauderman, Dabeeru C Rao, Hugues Aschard, and CHARGE Gene-lifestyle Interactions Working Group
Biomolecular condensates form spatially inhomogeneous network fluids, Furqan Dar, Samuel R Cohen, Diana M Mitrea, Aaron H Phillips, Gergely Nagy, Wellington C Leite, Christopher B Stanley, Jeong-Mo Choi, Richard W Kriwacki, and Rohit V Pappu
Single-cell T-cell receptor repertoire profiling in dogs, My H Hoang, Zachary L Skidmore, Hans Rindt, Shirley Chu, Bryan Fisk, Jennifer A Foltz, Catrina Fronick, Robert Fulton, Mingyi Zhou, Nathan J Bivens, Carol N Reinero, Todd A Fehniger, Malachi Griffith, Jeffrey N Bryan, and Obi L Griffith
Evidence and sources of placebo effects in transcranial direct current stimulation during a single session of visuospatial working memory practice, Andrew Hooyman, Nicole K Haikalis, Peiyuan Wang, Heidi M Schambra, Keith R Lohse, and Sydney Y Schaefer
Bioresorbable, wireless, passive sensors for continuous pH measurements and early detection of gastric leakage, Shuo Li, Yameng Xu, Ying Yan, Jorge Zárate Rodriguez, Mitchell A Pet, Chet W Hammill, Matthew R MacEwan, Wilson Z Ray, and et al.
SARS-CoV-2 Omicron BA.1 variant infection of human colon epithelial cells, Avan Antia, David M Alvarado, Qiru Zeng, Luis A Casorla-Perez, Deanna L Davis, Naomi M Sonnek, Matthew A Ciorba, and Siyuan Ding
Sleep and circadian biomarkers of postoperative delirium (SLEEP-POD): Protocol for a prospective and observational cohort study, Elizabeth Sugg, Elizabeth Gleeson, Sarah N Baker, Peng Li, Chenlu Gao, Ariel Mueller, Hao Deng, Shiqian Shen, Esteban Franco-Garcia, Richa Saxena, Erik S Musiek, Oluwaseun Akeju, Zhongcong Xie, Kun Hu, and Lei Gao
Antiviral cellular therapy for enhancing T-cell reconstitution before or after hematopoietic stem cell transplantation (ACES): A two-arm, open label phase II interventional trial of pediatric patients with risk factor assessment, Michael D Keller, Jeffrey J Bednarski, and et al.
Cellular geometry and epithelial-mesenchymal plasticity intersect with PIEZO1 in breast cancer cells, Choon Leng So, Mélanie Robitaille, Francisco Sadras, Michael H McCullough, Michael J G Milevskiy, Geoffrey J Goodhill, Sarah J Roberts-Thomson, and Gregory R Monteith
Encoding of visual objects in the human medial temporal lobe, Yue Wang, Runnan Cao, and Shuo Wang
Estimated health benefits, costs and cost-effectiveness of eliminating industrial trans-fatty acids in Nigeria: Cost-effectiveness analysis, Matti Marklund, Leopold N Aminde, Mary Njeri Wanjau, Boni M Ale, Adedayo E Ojo, Clementina E Okoro, Abimbola Adegboye, Liping Huang, J Lennert Veerman, Jason Hy Wu, Mark D Huffman, and Dike B Ojji
Host response during unresolved urinary tract infection alters female mammary tissue homeostasis through collagen deposition and TIMP1, Samantha Henry, Xue-Yan He, and et al.
Novel JAK inhibitors to reduce graft-versus-host disease after allogeneic hematopoietic cell transplantation in a preclinical mouse model, Sena Kim, Peter Ruminski, Megh Singh, Karl Staser, Kidist Ashami, Julie Ritchey, Sora Lim, John F DiPersio, and Jaebok Choi
Recruitment strategies in the Integration of Mobile Health into Sickle Cell Disease Care to Increase Hydroxyurea Utilization study (meSH): Multicenter survey study, Chinonyelum Nwosu, Hamda Khan, Rita Masese, Judith M Nocek, Siera Gollan, Taniya Varughese, Sarah Bourne, Cindy Clesca, Sara R Jacobs, Ana Baumann, Lisa M Klesges, Nirmish Shah, Jane S Hankins, and Matthew P Smeltzer
TOPMed imputed genomics enhances genomic atlas of the human proteome in brain, cerebrospinal fluid, and plasma, Heng Yi, Qijun Yang, Charlie Repaci, Cheolmin Matthew Lee, Gyujin Heo, Jigyasha Timsina, Priyanka Gorijala, Chengran Yang, John Budde, Lihua Wang, Carlos Cruchaga, and Yun Ju Sung
Evolution of the transforaminal lumbar interbody fusion (TLIF): From open to percutaneous to patient-specific, Peter N Drossopoulos, Favour C Ononogbu-Uche, Troy Q Tabarestani, Chuan-Ching Huang, Mounica Paturu, Anas Bardeesi, Wilson Z Ray, Christopher I Shaffrey, C Rory Goodwin, Melissa Erickson, John H Chi, and Muhammad M Abd-El-Barr
Chemotherapy activates inflammasomes to cause inflammation-associated bone loss, Chun Wang, Khushpreet Kaur, Canxin Xu, Yousef Abu-Amer, and Gabriel Mbalaviele
Impact of self-reported loss of balance and gait disturbance on outcomes following adult spinal deformity surgery, Bassel G Diebo, Munish C Gupta, and et al.
Multisensory flicker modulates widespread brain networks and reduces interictal epileptiform discharges, Lou T Blanpain, Eric R Cole, Emily Chen, James K Park, Michael Y Walelign, Robert E Gross, Brian T Cabaniss, Jon T Willie, and Annabelle C Singer
Use of barium for diagnosis of colonic perforation leads to challenging barium peritonitis, Ariana Naaseh, Jorge G Zarate Rodriguez, Matthew J McHale, Grace M Niziolek, Thoi H Ngo, John P Kirby, and Lindsay M Kranker
Bone canonical Wnt signaling is downregulated in type 2 diabetes and associates with higher advanced glycation end-products (AGEs) content and reduced bone strength, Giulia Leanza, Alec T Beeve, Erica L Scheller, Simon Y Tang, Roberto Civitelli, Nicola Napoli, and et al.
Innovation in non-invasive diagnosis and disease monitoring for meningiomas, Brianna Korte and Dimitrios Mathios
Lung type 3 innate lymphoid cells respond early following Mycobacterium tuberculosis infection, Shibali Das, Kuldeep Singh Chauhan, Mushtaq Ahmed, Sadia Akter, Lan Lu, Marco Colonna, and Shabaana A Khader
Mechanism of antagonist ligand binding to REV-ERBα, Mohammad Homaidur Rahman and Lamees Hegazy
Vaccine effectiveness against influenza A-associated hospitalization, organ failure, and death: United States, 2022-2023, Nathaniel M Lewis, Jennie H Kwon, and et al.
Constant-pH simulations with the polarizable atomic multipole AMOEBA force field, Andrew C Thiel, Matthew J Speranza, Sanika Jadhav, Lewis L Stevens, Daniel K Unruh, Pengyu Ren, Jay W Ponder, Jana Shen, and Michael J Schnieders
Transcription factor C/EBPα is required for the development of Ly6Chi monocytes but not Ly6Clo monocytes, Sunkyung Kim, Jing Chen, Feiya Ou, Tian-Tian Liu, Suin Jo, William E Gillanders, Theresa L Murphy, and Kenneth M Murphy
Blocking senescence and tolerogenic function of dendritic cells induced by γδ Treg cells enhances tumor-specific immunity for cancer immunotherapy, Fusheng Si, Xia Liu, Yan Tao, Yuanqin Zhang, Feiya Ma, Eddy C Hsueh, Sidharth V Puram, and Guangyong Peng
CSF biomarkers of immune activation and Alzheimer's disease for predicting cognitive impairment risk in the elderly, Francis Shue, Rachel Hendrix, Jason Ulrich, Rachel L Henson, William Knight, Chengjie Xiong, Jigyasha Timsina, Yun Ju Sung, Carlos Cruchaga, David M Holtzman, and et al.
Subcellular pathways through VGluT3-expressing mouse amacrine cells provide locally tuned object-motion-selective signals in the retina, Karl Friedrichsen, Jen-Chun Hsiang, Chin-I Lin, Liam McCoy, Katia Valkova, Daniel Kerschensteiner, and Josh L Morgan
Induction of viral mimicry upon loss of DHX9 and ADAR1 in breast cancer cells, Kyle A Cottrell, Sua Ryu, Jackson R Pierce, Luisangely Soto Torres, Holly E Bohlin, Angela M Schab, and Jason D Weber
VISTA checkpoint inhibition by pH-selective antibody SNS-101 with optimized safety and pharmacokinetic profiles enhances PD-1 response, Thomas Thisted, Yoshiko Takeuchi, Robert D Schreiber, and et al.
Perioperative mental health intervention for depression and anxiety symptoms in older adults study protocol: Design and methods for three linked randomised controlled trials, Katherine J Holzer, Kimberly A Bartosiak, Ryan P Calfee, Chet W Hammill, Simon Haroutounian, Benjamin D Kozower, Theresa A Cordner, Emily M Lenard, Kenneth E Freedland, Bethany R Tellor Pennington, J Philip Miller, Mary C Politi, Yi Zhang, Michael D Yingling, Ana A Baumann, Thomas Kannampallil, Julia A Schweiger, Sherry L McKinnon, Michael S Avidan, Eric J Lenze, Joanna Abraham, and et al.
A compendium of multi-omics data illuminating host responses to lethal human virus infections, Amie J Eisfeld, Larissa B Thackray, Qing Tan, Michael S Diamond, and et al.
Environmental and sociocultural factors are associated with pain-related brain structure among diverse individuals with chronic musculoskeletal pain: Intersectional considerations, Lisa H Domenico, Jared J Tanner, Angela M Mickle, Ellen L Terry, Cynthia Garvan, Song Lai, Hrishikesh Deshpande, Roland Staud, David Redden, Catherine C Price, Burel R Goodin, Roger B Fillingim, and Kimberly T Sibille
Abatacept pharmacokinetics and exposure response in patients hospitalized with COVID-19: A secondary analysis of the ACTIV-1 IM randomized clinical trial, Stephen J Balevic, Daniel K Benjamin, William G Powderly, P Brian Smith, Daniel Gonzalez, Matthew W McCarthy, Linda K Shaw, Christopher J Lindsell, Sam Bozzette, Daphne Williams, Benjamin P Linas, John Blamoun, Heta Javeri, Christoph P Hornik, and ACTIV-1 IM Study Group
A protective role for type I interferon signaling following infection with Mycobacterium tuberculosis carrying the rifampicin drug resistance-conferring RpoB mutation H445Y, Suhas Bobba, Kuldeep S. Chauhan, Sadia Akter, Shibali Das, Ekansh Mittal, Barun Mathema, Jennifer A. Philips, and Shabaana A. Khader
Brain high-throughput multi-omics data reveal molecular heterogeneity in Alzheimer's disease, Abdallah M. Eteleeb, Brenna C. Novotny, Carolina Soriano Tarraga, Christopher Sohn, Eliza Dhungel, Logan Brase, Aasritha Nallapu, Jared Buss, Fabiana Farias, Kristy Bergmann, Joseph Bradley, Joanne Norton, Jen Gentsch, Fengxian Wang, Albert A. Davis, John C. Morris, Celeste M. Karch, Richard J. Perrin, Bruno A. Benitez, and Oscar Harari
Cannabis oil extracts for chronic pain: What else can be learned from another structured prospective cohort?, Dorit Pud, Suhail Aamar, Bareket Schiff-Keren, Roee Sheinfeld, Silviu Brill, Dror Robinson, Yaakov Fogelman, George Habib, Haggai Sharon, Howard Amital, Boris Boltyansky, Simon Haroutounian, and Elon Eisenberg
Cholesterol 25-hydroxylase mediates neuroinflammation and neurodegeneration in a mouse model of tauopathy, Danira Toral-Rios, Justin M Long, Jason D Ulrich, Jinsheng Yu, Michael R Strickland, Xianlin Han, David M Holtzman, Anil G Cashikar, and Steven M Paul
Cognitive flexibility training for chronic pain: A randomized clinical study, Katherine J. Holzer, Marko S. Todorovic, Elizabeth A. Wilson, Aaron Steinberg, Michael S. Avidan, and Simon Haroutounian
Cognitive outcomes of children with sagittal craniosynostosis treated with either endoscopic or open calvarial vault surgery, Suresh N Magge, Annahita R Fotouhi, Virginia Allhusen, Brent R Collett, Gary B Skolnick, Sybill D Naidoo, Matthew D Smyth, Robert F Keating, Raj Vyas, Gary F Rogers, and Kamlesh B Patel
DNA combing versus DNA spreading and the separation of sister chromatids, Alice Meroni, Sophie E Wells, Carmen Fonseca, Arnab Ray Chaudhuri, Keith W Caldecott, and Alessandro Vindigni
Drug-induced liver injury in the elderly: Consensus statements and recommendations from the IQ-DILI Initiative, Eric B Cohen, Meenal Patwardhan, Ritu Raheja, David H Alpers, Raul J Andrade, Mark I Avigan, James H Lewis, Don C Rockey, Francis Chui, Alexandru M Iacob, Camila C Linardi, Arie Regev, Jesse Shick, and M Isabel Lucena
Exploring the association between weight loss-inducing medications and multiple sclerosis: Insights from the FDA adverse event reporting system database, Afsaneh Shirani, Anne H Cross, and Olaf Stuve
Highly accurate blood test for Alzheimer's disease is similar or superior to clinical cerebrospinal fluid tests, Nicolas R Barthélemy, Suzanne E Schindler, Yingxin He, Benjamin Saef, Rachel L Henson, Charles D Chen, Brian A Gordon, Yan Li, Tammie L S Benzinger, John C Morris, Randall J Bateman, and et al.
Incidence and mortality of COVID-19-associated invasive fungal infections among critically ill intubated patients: A multicenter retrospective cohort analysis, Julio C Zuniga-Moya, Benjamin Papadopoulos, Armaghan-E-Rehman Mansoor, Patrick B Mazi, Adriana M Rauseo, and Andrej Spec
Interstate highway connections and traced gun transfers between the 48 contiguous United States, Leah Roberts, Mark H Hoofnagle, Brady Bushover, Ariana N Gobaud, Christina A Mehranbod, Carolyn Fish, and Christopher N Morrison
Loncastuximab tesirine in relapsed/refractory diffuse large B-cell lymphoma: Long-term efficacy and safety from the phase II LOTIS-2 study, Paolo F. Caimi, Brad S Kahl, and et al.
Medicaid eligibility loss among dual-eligible beneficiaries before and during COVID-19 public health emergency, Yanlei Ma, Eric T Roberts, Kenton J Johnston, E John Orav, and Jose F Figueroa
MYSM1 attenuates DNA damage signals triggered by physiologic and genotoxic DNA breaks, Brendan Mathias, David O'Leary, Nermina Saucier, Faiz Ahmad, Lynn S White, Le'Mark Russell, Marwan Shinawi, Matthew J Smith, Roshini S Abraham, Megan A Cooper, Maleewan Kitcharoensakkul, Abby M Green, and Jeffrey J Bednarski
Neighborhood disadvantage and breast cancer-specific survival in the US, Neha Goel, Alexandra E Hernandez, and Angela Mazul
Neurosteroids and their potential as a safer class of general anesthetics, Hiroki Tateiwa and Alex S Evers
Novel SGCE mutation in a patient with myoclonus-dystonia: A case report, Eva Klinman, Catherine Gooch, Joel S. Perlmutter, Albert A. Davis, and Baijayanta Maiti
Prevotella copri and microbiota members mediate the beneficial effects of a therapeutic food for malnutrition, Hao-Wei Chang, Evan M Lee, Yi Wang, Cyrus Zhou, Kali M Pruss, Suzanne Henrissat, Robert Y Chen, Clara Kao, Matthew C Hibberd, Hannah M Lynn, Daniel M Webber, Marie Crane, Jiye Cheng, Ye Chen, Jeffrey I Gordon, and et al.
Reliability and validity of smartphone cognitive testing for frontotemporal lobar degeneration, Adam M Staffaroni, Nupur Ghoshal, Jason Hassenstab, and et al.
Sensitive MRD detection from lymphatic fluid after surgery in HPV-associated oropharyngeal cancer, Noah Earland, Nicholas P Semenkovich, Ricardo J Ramirez, Peter K Harris, Andrew I Hearn, Matthew Inkman, Jeffrey J Szymanski, Benjamin M Wahle, Kevin Chen, Irfan Alahi, Gabris Ni, Andrew Chen, Jin Zhang, Aadel A Chaudhuri, and et al.
Severity of respiratory syncytial virus vs COVID-19 and influenza among hospitalized US adults, Diya Surie, Jennie H Kwon, and et al.
2024 European Heart Rhythm Association/Heart Rhythm Society/Asia Pacific Heart Rhythm Society/Latin American Heart Rhythm Society expert consensus statement on catheter and surgical ablation of atrial fibrillation, Stylianos Tzeis, Ralph J Damiano, and et al.
ArCH: Improving the performance of clonal hematopoiesis variant calling and interpretation, Irenaeus C C Chan, Alex Panchot, Evelyn Schmidt, Brian J Wiley, Jie Liu, Kimberly Turner, Duc Tran, J Scott Beeler, Armel Landry Batchi-Bouyou, Daniel C Link, Kelly L Bolton, and et al.
Structure of alpha-synuclein fibrils derived from human Lewy body dementia tissue, Dhruva D Dhavale, Katherine Basore, Isabelle R Gordon, Jialu Liu, Jennifer Y O'Shea, Michael J Rau, Zachary Smith, Brock Summers, Richard J Perrin, Joel S Perlmutter, James A J Fitzpatrick, Paul T Kotzbauer, and et al.
Comparative lipidome study of maternal plasma, milk, and lamb plasma in sheep, Soundara Viveka Thangaraj, Adel Ghnenis, Brooke Pallas, Arpita Kalla Vyas, Brigid Gregg, and Vasantha Padmanabhan
Fibrinolytic-deficiencies predispose hosts to septicemia from a catheter-associated UTI, Jonathan J Molina, Wei Xu, Karla Bergeron, Aleksandra Klim, Michael G Caparon, Scott J Hultgren, Alana Desai, and et al.
Efficacy and feasibility of short-stretch compression therapy for filarial lymphedema in Sri Lanka, Jaimee M Hall, Nirmitha Lalindi De Silva, Janaka Ruben, Sandani S Thilakarathne, Thishan Channa Yahathugoda, and Philip J Budge
Impact of imaging frequency on progression-free survival in Alliance trials enrolling patients with follicular lymphoma, Sarah C Rutherford, Jun Yin, Levi D Pederson, Kristie A Blum, Peter Martin, Sin-Ho Jung, Barbara Grant, Cara Rosenbaum, Bruce D Cheson, Nancy L Bartlett, Sumithra J Mandrekar, and John P Leonard
Intergenerational protective anti-gut commensal immunoglobulin G originates in early life, Brigida Rusconi, Adina K Bard, Ryan McDonough, Angel M Kindsvogel, Jacqueline D Wang, Sreeram Udayan, Keely G McDonald, Rodney D Newberry, and Phillip I Tarr
Next generation microfluidics: Fulfilling the promise of lab-on-a-chip technologies, Umut A Gurkan, Jorge Di Paola, and et al.
Phase 2 study of add-on parsaclisib for patients with myelofibrosis and suboptimal response to ruxolitinib: Final results, Abdulraheem Yacoub, Stephen T Oh, and et al.
Targeting CXCR4, VLA-4, and CXCR2 for hematopoietic stem cell mobilization, Daniel Cancilla, Michael P Rettig, Darja Karpova, Haresh Thakellapalli, Megh Singh, Marvin J Meyers, Peter G Ruminski, Stephanie Christ, Ezhilarasi Chendamarai, Feng Gao, Leah Gehrs, Julie K Ritchey, Michael Prinsen, and John F DiPersio
Distal extent of resection in type A dissection: Keeping it simple, Marc R Moon and Puja Kachroo
The disordered N-terminal tail of SARS-CoV-2 Nucleocapsid protein forms a dynamic complex with RNA, Jasmine Cubuk, Jhullian J Alston, J Jeremías Incicco, Alex S Holehouse, Kathleen B Hall, Melissa D Stuchell-Brereton, and Andrea Soranno
Application of learned ideal observers for estimating task-based performance bounds for computed imaging systems, Kaiyan Li, Umberto Villa, Hua Li, and Mark A. Anastasio
Combined KRAS-MAPK pathway inhibitors and HER2-directed drug conjugate is efficacious in pancreatic cancer, Ashenafi Bulle, Peng Liu, Kuljeet Seehra, Sapana Bansod, Yali Chen, Kiran Zahra, Vikas Somani, Iftikhar Ali Khawar, Hung-Po Chen, Paarth B Dodhiawala, Lin Li, Yutong Geng, Chia-Kuei Mo, Jay Mahsl, Li Ding, Ramaswamy Govindan, Sherri Davies, Jacqueline Mudd, William G Hawkins, Ryan C Fields, David G DeNardo, Jason M Held, Patrick M Grierson, Andrea Wang-Gillam, Marianna B Ruzinova, Kian-Huat Lim, and et al.
Epitope mapping of Japanese encephalitis virus neutralizing antibodies by native mass spectrometry and hydrogen/deuterium exchange, Jagat Adhikari, James Heffernan, Melissa Edeling, Estefania Fernandez, Prashant N Jethva, Michael S Diamond, Daved H Fremont, and Michael L Gross
Mapping human tissues with highly multiplexed RNA in situ hybridization, Kian Kalhor, Amanda Knoten, Joseph P Gaut, Sanjay Jain, and et al.
Pathogenic variants in CRX have distinct cis-regulatory effects on enhancers and silencers in photoreceptors, James L Shepherdson, Ryan Z Friedman, Yiqiao Zheng, Chi Sun, Inez Y Oh, David M Granas, Barak A Cohen, Shiming Chen, and Michael A White
Predation without direction selectivity, Jenna Krizan, Xiayingfang Song, Michael J Fitzpatrick, Ning Shen, Florentina Soto, and Daniel Kerschensteiner
Prediction of 3-dimensional coverage surface area of the femoral head in hip dysplasia through conventional computed tomography, Tomoyuki Kamenaga, Lucas Ritacco, Pablo A Slullitel, Chadi Nahal, Jeffrey J Nepple, John C Clohisy, and Cecilia Pascual-Garrido
Two DOT1 enzymes cooperatively mediate efficient ubiquitin-independent histone H3 lysine 76 tri-methylation in kinetoplastids, Victoria S Frisbie, Hideharu Hashimoto, Yixuan Xie, Francisca N De Luna Vitorino, Josue Baeza, Tam Nguyen, Zhangerjiao Yuan, Janna Kiselar, Benjamin A Garcia, and Erik W Debler
HTRA1 disaggregates α-synuclein amyloid fibrils and converts them into non-toxic and seeding incompetent species, Sheng Chen, Anuradhika Puri, Braxton Bell, Joseph Fritsche, Hector H Palacios, Maurie Balch, Macy L Sprunger, Matthew K Howard, Jeremy J Ryan, Jessica N Haines, Gary J Patti, Albert A Davis, and Meredith E Jackrel
Sequence-structure-function characterization of the emerging tetracycline destructase family of antibiotic resistance enzymes, Kevin S Blake, Hirdesh Kumar, Anisha Loganathan, Emily E Williford, Luke Diorio-Toth, Yao-Peng Xue, Wai Kwan Tang, Tayte P Campbell, David D Chong, Steven Angtuaco, Timothy A Wencewicz, Niraj H Tolia, and Gautam Dantas
The novel drug candidate S2/IAPinh improves survival in models of pancreatic and ovarian cancer, Takaomi Hagi, Suwanna Vangveravong, Rony Takchi, Qingqing Gong, S Peter Goedegebuure, Herve Tiriac, Brian A Van Tine, Matthew A Powell, William G Hawkins, and Dirk Spitzer
Simulation-based analysis of trial design in regional anesthesia, Melisa Pasli, Dmitry Tumin, and Ryan Guffey
Gestational testosterone excess early to mid-pregnancy disrupts maternal lipid homeostasis and activates biosynthesis of phosphoinositides and phosphatidylethanolamines in sheep, Nadia Saadat, Brooke Pallas, Joseph Ciarelli, Arpita Kalla Vyas, and Vasantha Padmanabhan
A phase I trial of pevonedistat in combination with ruxolitinib for the treatment of myelofibrosis, Tim Kong, Nicole Gaudin, Karyn Gordon, Maggie J Cox, Amy W Zhou, and Stephen T Oh
Genomic surveillance of Clostridioides difficile transmission and virulence in a healthcare setting, Erin P Newcomer, Skye R S Fishbein, Kailun Zhang, Tiffany Hink, Kimberly A Reske, Candice Cass, Zainab H Iqbal, Emily L Struttmann, Carey-Ann D Burnham, Erik R Dubberke, and Gautam Dantas
Inducing vulnerability to InhA inhibition restores isoniazid susceptibility in drug-resistant Mycobacterium tuberculosis, Gregory A Harrison, Erin R Wang, Kevin Cho, Yassin Mreyoud, Souvik Sarkar, Fredrik Almqvist, Gary J Patti, and Christina L Stallings
The identification of small molecule inhibitors with anthelmintic activities that target conserved proteins among ruminant gastrointestinal nematodes, Hyeim Jung, Dante Zarlenga, John C Martin, Peter Geldhof, Kymberlie Hallsworth-Pepin, and Makedonka Mitreva
Durable immunity to EBV after rituximab and third-party LMP-specific T cells: A Children's Oncology Group study, Birte Wistinghausen, Robert J Hayashi, and et al.
Germline knockout of Nr2e3 protects photoreceptors in three distinct mouse models of retinal degeneration, Alexander V Kolesnikov, Daniel P Murphy, Joseph C Corbo, and Vladimir J Kefalov
Guiding principles for adolescent web-based portal access policies: Interviews with informatics administrators, Bryan Sisk, Alison L Antes, Christine Bereitschaft, Madi Enloe, Fabienne Bourgeois, and James DuBois
