Submissions from 2023
Membrane phospholipids control gating of the mechanosensitive potassium leak channel TREK1, Philipp A M Schmidpeter, John T Petroff 2nd, Leila Khajoueinejad, Aboubacar Wague, Cheryl Frankfater, Wayland W L Cheng, Crina M Nimigean, and Paul M Riegelhaupt
[18F]Tosyl fluoride as a versatile [18F]fluoride source for the preparation of 18F-labeled radiopharmaceuticals, Dong Zhou, Wenhua Chu, Jinbin Xu, Sally Schwarz, and John A Katzenellenbogen
Allogeneic natural killer cell therapy, Melissa M Berrien-Elliott, Miriam T Jacobs, and Todd A Fehniger
Skeletal dysplasia-causing TRPV4 mutations suppress the hypertrophic differentiation of human iPSC-derived chondrocytes, Amanda R Dicks, Grigory I Maksaev, Zainab Harissa, Alireza Savadipour, Ruhang Tang, Nancy Steward, Wolfgang Liedtke, Colin G Nichols, Chia-Lung Wu, and Farshid Guilak
The Toxoplasma micropore mediates endocytosis for selective nutrient salvage from host cell compartments, Wenyan Wan, Hui Dong, De-Hua Lai, Jiong Yang, Kai He, Xiaoyan Tang, Qun Liu, Geoff Hide, Xing-Quan Zhu, L David Sibley, Zhao-Rong Lun, and Shaojun Long
Uncovering the complex genetic architecture of human plasma lipidome using machine learning methods, Miikael Lehtimäki, Binisha H Mishra, Coral Del-Val, Leo-Pekka Lyytikäinen, Mika Kähönen, C Robert Cloninger, Olli T Raitakari, Reijo Laaksonen, Igor Zwir, Terho Lehtimäki, and Pashupati P Mishra
Effects of particle diameter and inlet flow rate on gas-solid flow patterns of fluidized bed, Zhenjiang Zhao, Ling Zhou, Ling Bai, Wanning Lv, and Ramesh K Agarwal
Efficacy and safety of non-steroidal anti-inflammatory drugs (NSAIDs) for the treatment of acute pain after orthopedic trauma: A practice management guideline from the Eastern Association for the Surgery of Trauma and the Orthopedic Trauma Association, Patrick B. Murphy, Anna Miller, and et al.
The status of digital pathology and associated infrastructure within Alzheimer's Disease Centers, Rebeca Scalco, Richard J Perrin, and et al.
TCR-engineered adoptive cell therapy effectively treats intracranial murine glioblastoma, Maximilian O. Schaettler, Rupen Desai, Anthony Z. Wang, Alexandra J. Livingstone, Dale K. Kobayashi, Andrew T. Coxon, Jay A. Bowman-Kirigin, Connor J. Liu, Mao Li, Diane E. Bender, Michael J. White, David M. Kranz, Tanner M. Johanns, and Gavin P. Dunn
Developmental programming: Adverse sexually dimorphic transcriptional programming of gestational testosterone excess in cardiac left ventricle of fetal sheep, Venkateswaran Ramamoorthi Elangovan, Nadia Saadat, Adel Ghnenis, Vasantha Padmanabhan, and Arpita K Vyas
FMR1 mutation alters the early development of sensory coding and hunting and social behaviors in larval zebrafish, Shuyu I Zhu, Michael H McCullough, Zac Pujic, Jordan Sibberas, Biao Sun, Thomas Darveniza, Bianca Bucknall, Lilach Avitan, and Geoffrey J Goodhill
SVEP1 is an endogenous ligand for the orphan receptor PEAR1, Jared S Elenbaas, Upasana Pudupakkam, Katrina J Ashworth, Chul Joo Kang, Ved Patel, Katherine Santana, In-Hyuk Jung, Paul C Lee, Kendall H Burks, Junedh M Amrute, Robert P Mecham, Carmen M Halabi, Arturo Aliso, Jorge Di Paola, and Nathan O Stitziel
mRNA vaccine mitigates SARS-CoV-2 infections and COVID-19, Christina M. Kackos, Sherri L. Surman, Bart G. Jones, Robert E. Sealy, Trushar Jeevan, Christopher J H Davitt, Sergei Pustylnikov, Tamarand L. Darling, Adrianus C M Boon, Julia L. Hurwitz, Marcelo M. Samsa, and Richard J. Webby
Staphylococcus aureus breast implant infection isolates display recalcitrance to antibiotic pocket irrigants, Jesus M. Duran Ramirez, Jana Gomez, Blake M. Hanson, Taha Isa, Terence M. Myckatyn, and Jennifer N. Walker
Amniotes co-opt intrinsic genetic instability to protect germ-line genome integrity, Yu H Sun, Xiaoyu Zhuo, and et al.
Outcomes in participants with ventilated nosocomial pneumonia and organ failure treated with ceftolozane/tazobactam versus meropenem: A subset analysis of the phase 3, randomized, controlled ASPECT-NP trial, Ignacio Martin-Loeches, Andrew F Shorr, Richard G Wunderink, Marin H Kollef, Jean-François Timsit, Brian Yu, Jennifer A Huntington, Erin Jensen, and Christopher J Bruno
Phase Ib study of telisotuzumab vedotin in combination with erlotinib in patients with c-Met protein-expressing non-small-cell lung cancer, D Ross Camidge, Daniel Morgensztern, and et al.
Retinoid X receptor promotes hematopoietic stem cell fitness and quiescence and preserves hematopoietic homeostasis, María Piedad Menéndez-Gutiérrez, Jesús Porcuna, Ramesh Nayak, Ana Paredes, Haixia Niu, Vanessa Núñez, Aditi Paranjpe, Manuel J Gómez, Anukana Bhattacharjee, Daniel J Schnell, Fátima Sánchez-Cabo, John S Welch, Nathan Salomonis, Jose A Cancelas, and Mercedes Ricote
Body mass index and molecular subtypes of colorectal cancer, Neil Murphy, Yin Cao, and et al.
Incidence, attributable mortality, and healthcare and out-of-pocket costs of Clostridioides difficile infection in US Medicare Advantage Enrollees, Holly Yu, Tamuno Alfred, Jennifer L Nguyen, Jingying Zhou, and Margaret A Olsen
Protection of messenger RNA vaccines against hospitalized coronavirus disease 2019 in adults over the first year following authorization in the United States, Mark W Tenforde, Hilary M Babcock, Jennie H Kwon, and et al.
The impact of universal glove and gown use on Clostridioides difficile acquisition: A cluster-randomized trial, Daniel J Morgan, Erik R Dubberke, Tiffany Hink, Gwen Paszkiewicz, Carey-Ann D Burnham, Lisa Pineles, Larry Magder, J Kristie Johnson, Surbhi Leekha, and Anthony D Harris
Structures of human gastrin-releasing peptide receptors bound to antagonist and agonist for cancer and itch therapy, Shuman Peng, Yuting Zhan, Dongqi Zhang, Lu Ren, Anqi Chen, Zhou-Feng Chen, and Haitao Zhang
Antitumour activity of neratinib in patients with HER2-mutant advanced biliary tract cancers, James J Harding, Haeseong Park, and et al.
Ion channel regulation of gut immunity, Jing Feng, Zili Xie, and Hongzhen Hu
The p97-UBXD8 complex regulates ER-Mitochondria contact sites by altering membrane lipid saturation and composition, Rakesh Ganji, Joao A Paulo, Yuecheng Xi, Ian Kline, Jiang Zhu, Christoph S Clemen, Conrad C Weihl, John G Purdy, Steve P Gygi, and Malavika Raman
Widespread contribution of transposable elements to the rewiring of mammalian 3D genomes, Mayank N K Choudhary, Kara Quaid, Xiaoyun Xing, Heather Schmidt, and Ting Wang
Microbes, histology, blood analysis, enterotoxins, and cytokines: Findings from the ASERF Systemic Symptoms in Women-Biospecimen Analysis Study: Part 3, Patricia McGuire, Caroline Glicksman, Roger Wixtrom, C James Sung, Robert Hamilton, Marisa Lawrence, Melinda Haws, Sarah Ferenz, and Marshall Kadin
NetProphet 3: A machine learning framework for transcription factor network mapping and multi-omics integration, Dhoha Abid and Michael R Brent
SSRIs differentially modulate the effects of pro-inflammatory stimulation on hippocampal plasticity and memory via sigma 1 receptors and neurosteroids, Yukitoshi Izumi, Angela M Reiersen, Eric J Lenze, Steven J Mennerick, and Charles F Zorumski
BrainWAVE: A flexible method for noninvasive stimulation of brain rhythms across species, Matthew K. Attokaren, Nuri Jeong, Lou Blanpain, Abigail L. Paulson, Kristie M. Garza, Ben Borron, Michael Walelign, Jon Willie, and Annabelle C. Singer
Dissecting cell identity via network inference and in silico gene perturbation, Kenji Kamimoto, Blerta Stringa, Christy M Hoffmann, Kunal Jindal, Lilianna Solnica-Krezel, and Samantha A Morris
Final results from a phase 2b randomized, placebo-controlled clinical trial of RBX2660: A microbiota-based drug for the prevention of recurrent Clostridioides difficile infection, Erik R Dubberke, Robert Orenstein, Sahil Khanna, Beth Guthmueller, and Christine Lee
Functional and clinical studies reveal pathophysiological complexity of CLCN4-related neurodevelopmental condition, Elizabeth E Palmer, Linda J Richards, and et al.
Identification of bradycardia following remdesivir administration through the US Food and Drug Administration American College of Medical Toxicology COVID-19 Toxic Pharmacovigilance Project, Jason M Devgun, Rongmei Zhang, Jeffrey Brent, Paul Wax, Keith Burkhart, Alison Meyn, Sharan Campleman, Stephanie Abston, Kim Aldy, and Toxicology Investigators Consortium FACT Study Group
In vivo editing of the pan-endothelium by immunity evading simian adenoviral vector, Reka Lorincz, Aluet Borrego Alvarez, Christopher J Walkey, Samir A Mendonça, Zhi Hong Lu, Alexa E Martinez, Cecilia Ljungberg, Jason D Heaney, William R Lagor, and David T Curiel
Knockout of TSC2 in Nav1.8+ neurons predisposes to the onset of normal weight obesity, Jennifer M Brazill, David Shin, Kristann Magee, Anurag Majumdar, Ivana R Shen, Valeria Cavalli, and Erica L Scheller
Missed opportunities in the diagnosis of tuberculosis meningitis, Niamh Simmons, Margaret A Olsen, Joanna Buss, Thomas C Bailey, and Carlos Mejia-Chew
Multi-ancestry transcriptome-wide association analyses yield insights into tobacco use biology and drug repurposing, Fang Chen, Lisa de Las Fuentes, and et al.
Navigating care for rare diseases: Caregiver and patient advice for families and clinicians managing care for vascular malformations, Anna M Kerr, Christine Bereitschaft, Kayla M Duty, and Bryan A Sisk
Primary central nervous system germ cell tumors in children and young adults: A review of controversies in diagnostic and treatment approach, Kee Kiat Yeo, Sumanth Nagabushan, Girish Dhall, and Mohamed S Abdelbaki
Real-world COVID-19 vaccine effectiveness against the Omicron BA.2 variant in a SARS-CoV-2 infection-naive population, Jonathan J Lau, Chao Wu, Gaya K Amarasinghe, and et al.
The NTPase activity of the double FYVE domain-containing protein 1 regulates lipid droplet metabolism., Victoria A. Ismail, Teri Naismith, and David J. Kast
The tetraspanin transmembrane protein CD53 mediates dyslipidemia and integrates inflammatory and metabolic signaling in hepatocytes, Cassandra B Higgins, Joshua A Adams, Matthew H Ward, Zev J Greenberg, Małgorzata Milewska, Jiameng Sun, Yiming Zhang, Luana Chiquetto Paracatu, Qian Dong, Samuel Ballentine, Weikai Li, Ilona Wandzik, Laura G Schuettpelz, and Brian J DeBosch
Effect of histology on stereotactic body radiotherapy for non-small cell lung cancer oligometastatic pulmonary lesions, Alexander J. Allen, Dominic A. Labella, Roman O. Kowalchuk, Michael R. Waters, and Charles R. Kersh
Drug specificity and affinity are encoded in the probability of cryptic pocket opening in myosin motor domains, Artur Meller, Jeffrey M Lotthammer, Louis G Smith, Borna Novak, Lindsey A Lee, Catherine C Kuhn, Lina Greenberg, Leslie A Leinwand, Michael J Greenberg, and Gregory R Bowman
Gold nanoparticle-enhanced X-ray microtomography of the rodent reveals region-specific cerebrospinal fluid circulation in the brain, Shelei Pan, Peter H Yang, Dakota DeFreitas, Sruthi Ramagiri, Peter O Bayguinov, Carl D Hacker, Abraham Z Snyder, Jackson Wilborn, Hengbo Huang, Gretchen M Koller, Dhvanii K Raval, Grace L Halupnik, Sanja Sviben, Rui Tang, Gabriel Haller, James D Quirk, James A J Fitzpatrick, Prabagaran Esakky, Jennifer M Strahle, and et al.
Cross center single-cell RNA sequencing study of the immune microenvironment in rapid progressing multiple myeloma, William Pilcher, Reyka G Jayasinghe, Lijun Yao, Mark Fiala, Ravi Vij, Li Ding, and et al.
Enhanced VWF clearance in low VWF pathogenesis: Limitations of the VWFpp/VWF:Ag ratio and clinical significance, Dearbhla Doherty, Michelle Lavin, Mary Byrne, Margaret Nolan, Jamie M O'Sullivan, Kevin Ryan, Niamh M O'Connell, Sandra L Haberichter, Pamela A Christopherson, Jorge Di Paola, Paula D James, and James S O'Donnell
Gut microbiota and microbiota-derived metabolites promotes endometriosis, Sangappa B Chadchan, Sumanta K Naik, Pooja Popli, Chandni Talwar, Satwikreddy Putluri, Chandrasekhar R Ambati, Michael A Lint, Andrew L Kau, Christina L Stallings, and Ramakrishna Kommagani
A selective inhibitor of the sperm-specific potassium channel SLO3 impairs human sperm function, Maximilian Lyon, Ping Li, Juan J Ferreira, Aluet Borrego Alvarez, Lis C Puga Molina, Pascale Lybaert, Saayli Khambekar, Alicia Liu, Celia M Santi, and et al.
Distinct clonal identities of B-ALLs arising after lenolidomide therapy for multiple myeloma, Erica K Barnell, Zachary L Skidmore, Kenneth F Newcomer, Monique Chavez, Katie M Campbell, Kelsy C Cotto, Nicholas C Spies, Marianna B Ruzinova, Tianjiao Wang, Brooj Abro, Bijal A Parikh, Eric J Duncavage, John L Frater, Yi-Shan Lee, Anjum Hassan, Justin A King, Daniel R Kohnen, Mark A Fiala, John S Welch, Geoffrey L Uy, Kiran Vij, Ravi Vij, Malachi Griffith, Obi L Griffith, Lukas D Wartman, and et al.
E. coli catheter-associated urinary tract infections are associated with distinctive virulence and biofilm gene determinants, Zongsen Zou, Robert F. Potter, William H. McCoy, John A. Wildenthal, George L. Katumba, Peter J. Mucha, Gautam Dantas, and Jeffrey P. Henderson
Structure-function correlates of fibrinogen binding by Acinetobacter adhesins critical in catheter-associated urinary tract infections, Kevin O Tamadonfar, Gisela Di Venanzio, Jerome S Pinkner, Karen W Dodson, Vasilios Kalas, Maxwell I Zimmerman, Jesus Bazan Villicana, Gregory R Bowman, Mario F Feldman, and Scott J Hultgren
Lateral line ablation by ototoxic compounds results in distinct rheotaxis profiles in larval zebrafish, Kyle C Newton, Dovi Kacev, Simon R O Nilsson, Allison L Saettele, Sam A Golden, and Lavinia Sheets
Synthetic biology design as a paradigm shift toward manufacturing affordable adeno-associated virus gene therapies, Logan Thrasher Collins, Selvarangan Ponnazhagan, and David T Curiel
Semantic wikis as flexible database interfaces for biomedical applications, Marco Falda, Manfredo Atzori, and Maurizio Corbetta
Urine cell-free DNA multi-omics to detect MRD and predict survival in bladder cancer patients, Pradeep S Chauhan, Alexander Shiang, Irfan Alahi, Wenjia Feng, Cayce Nawaf, Kevin Chen, Peter K Harris, Faridi Qaium, Casey Hatscher, Anna Antiporda, Lindsey Brunt, Lindsey R Mayer, Brian C Baumann, Eric H Kim, Melissa A Reimers, Zachary L Smith, Aadel A Chaudhuri, and et al.
Epigenetic resetting in the human germ line entails histone modification remodeling, Wolfram H Gruhn, Walfred W C Tang, Sabine Dietmann, João P Alves-Lopes, Christopher A Penfold, Frederick C K Wong, Navin B Ramakrishna, and M Azim Surani
Conserved angio-immune subtypes of the tumor microenvironment predict response to immune checkpoint blockade therapy, Madhav Subramanian, Ashraf Ul Kabir, Derek Barisas, Karen Krchma, and Kyunghee Choi
Differential effects of anti-CD20 therapy on CD4 and CD8 T cells and implication of CD20-expressing CD8 T cells in MS disease activity, Koji Shinoda, Anne H Cross, and et al.
Entry receptors - The gateway to alphavirus infection, Ofer Zimmerman, Autumn C. Holmes, Natasha M. Kafai, Lucas J. Adams, and Michael S. Diamond
GluA3 subunits are required for appropriate assembly of AMPAR GluA2 and GluA4 subunits on cochlear afferent synapses and for presynaptic ribbon modiolar-pillar morphology, Mark A Rutherford, Atri Bhattacharyya, Maolei Xiao, Hou-Ming Cai, Indra Pal, and Maria Eulalia Rubio
Posoleucel, an allogeneic, off-the-shelf multivirus-specific T-cell therapy, for the treatment of refractory viral infections in the post-HCT setting, Thomas Pfeiffer and et al.
prM-reactive antibodies reveal a role for partially mature virions in dengue virus pathogenesis, Kimberly A Dowd, Laura A VanBlargan, Rita E Chen, Bradley M Whitener, Jennifer Govero, Soila Sukupolvi-Petty, Michael S Diamond, and et al.
Endogenous retrovirus RNA expression differences between race, stage and HPV status offer improved prognostication among women with cervical cancer, Jill Alldredge, Vinay Kumar, James Nguyen, Brooke E Sanders, Karina Gomez, Kay Jayachandran, Jin Zhang, Julie Schwarz, and Farah Rahmatpanah
Long-term hematologic improvement in a patient with cytopenic myelofibrosis treated with pacritinib, Abdulraheem Yacoub, Ruben A Mesa, and Stephen T Oh
Combining IVUS + OCT data, biomechanical models and machine learning method for accurate coronary plaque morphology quantification and cap thickness and stress/strain index predictions, Rui Lv, Liang Wang, Akiko Maehara, Mitsuaki Matsumura, Xiaoya Guo, Habib Samady, Don P Giddens, Jie Zheng, Gary S Mintz, and Dalin Tang
Students stress patterns in a Kenyan socio-cultural and economic context: Toward a public health intervention, Victoria N Mutiso, David M Ndetei, Esther N Muia, Christine Musyimi, Monicah Masake, Tom L Osborn, Andre Sourander, John R Weisz, and Daniel Mamah
Childhood adversities and risk of posttraumatic stress disorder and major depression following a motor vehicle collision in adulthood, H N Ziobrowski, S L House, D M Barch, and et al.
Dry eye disease in mice activates adaptive corneal epithelial regeneration distinct from constitutive renewal in homeostasis, Joseph B Lin, Xiaolei Shen, Charles W Pfeifer, Fion Shiau, Andrea Santeford, Philip A Ruzycki, Brian S Clark, Qin Liu, Andrew J W Huang, and Rajendra S Apte
Gene regulatory network reconfiguration in direct lineage reprogramming, Kenji Kamimoto, Mohd Tayyab Adil, Kunal Jindal, Christy M Hoffmann, Wenjun Kong, Xue Yang, and Samantha A Morris
Postibrutinib relapse outcomes for patients with marginal zone lymphoma, Narendranath Epperla, Lauren Shea, Nancy L Bartlett, and et al.
A Cdh3-β-catenin-laminin signaling axis in a subset of breast tumor leader cells control leader cell polarization and directional collective migration, Priscilla Y Hwang, Jairaj Mathur, Yanyang Cao, Jose Almeida, Jiayu Ye, Vasilios Morikis, Daphne Cornish, Maria Clarke, Sheila A Stewart, Amit Pathak, and Gregory D Longmore
Docosahexaenoic acid stability in ready-to-use therapeutic food, Genevieve James, Kevin Stephenson, Meghan Callaghan-Gillespie, Mohamed Tabita Kamara, Hui Gyu Park, J Thomas Brenna, and Mark J Manary
Fungal assisted valorisation of polymeric lignin: Mechanism, enzymes and perspectives, Kavya Dashora, Meghana Gattupalli, Gyan Datta Tripathi, Zoya Javed, Shweta Singh, Maria Tuohy, Prakash Kumar Sarangi, Deepti Diwan, Harikesh B. Singh, and Vijai Kumar Gupta
Gene-folic acid interactions and risk of conotruncal heart defects: Results from the National Birth Defects Prevention Study, Daniel M Webber, Ming Li, Stewart L MacLeod, Xinyu Tang, Joseph W Levy, Mohammad A Karim, Stephen W Erickson, Charlotte A Hobbs, and The National Birth Defects Prevention Study
Histopathologic and proteogenomic heterogeneity reveals features of clear cell renal cell carcinoma aggressiveness, Yize Li, Yige Wu, Rita Jiu-Hsien Lu, Siqi Chen, Yanyan Zhao, Wagma Caravan, Nataly Naser Al Deen, Matthew A Wyczalkowski, Michael C Wendl, Melissa A Reimers, Russell Pachynski, Brian A Van Tine, Feng Chen, Li Ding, and et al.
Relations of current and past cancer with severe outcomes among 104,590 hospitalized COVID-19 patients: The COVID EHR cohort at the University of Wisconsin, Margaret B Nolan, Li-Shiun Chen, and et al.
Discovery and characterization of a new class of O-linking oligosaccharyltransferases from the Moraxellaceae family, Cory J Knoot, Paeton L Wantuch, Lloyd S Robinson, David A Rosen, Nichollas E Scott, and Christian M Harding
Silencing miR-146a-5p protects against injury-induced osteoarthritis in mice, Haocheng Qin, Cuicui Wang, Yonghua He, Aiwu Lu, Tiandao Li, Bo Zhang, and Jie Shen
Use of serial smartphone-based assessments to characterize diverse neuropsychiatric symptom trajectories in a large trauma survivor cohort, Francesca L Beaudoin, Stacey L House, Deanna M Barch, and et al.
A phase II study of palbociclib plus letrozole plus trastuzumab as neoadjuvant treatment for clinical stages II and III ER+ HER2+ breast cancer (PALTAN), Foluso O Ademuyiwa, Jingqin Luo, Yu Tao, Jeremy Hoog, Marie L Laury, Tracy Summa, Trish Hammerschmidt, Zhanfang Guo, Ashley Frith, Katherine Weilbaecher, Mateusz Opyrchal, Rebecca Aft, Katherine Clifton, Rama Suresh, Nusayba Bagegni, Ian S Hagemann, Michael D Iglesia, Cynthia X Ma, and et al.
CIViCdb 2022: Evolution of an open-access cancer variant interpretation knowledgebase, Kilannin Krysiak, Arpad M Danos, Jason Saliba, Joshua F McMichael, Adam C Coffman, Susanna Kiwala, Erica K Barnell, Lana Sheta, Lynzey Kujan, Shahil Pema, Nicholas C Spies, Kaitlin A Clark, Ajay C Venigalla, Avila Suda, Benjamin J Ainscough, Haolin Shen, Alex R Marr, My H Hoang, Kartik Singhal, Mariam Khanfar, Brian V Li, Katie M Campbell, Kelsy C Cotto, Zachary L Skidmore, Jason R Walker, Malachi Griffith, Obi L Griffith, and et al.
Conformational plasticity of NaK2K and TREK2 potassium channel selectivity filters, Marcos Matamoros, Xue Wen Ng, Joshua B Brettmann, David W Piston, and Colin G Nichols
Excretory/secretory proteome of females and males of the hookworm Ancylostoma ceylanicum, Samuel C Uzoechi, Bruce A Rosa, Kumar Sachin Singh, Young-Jun Choi, Bethany K Bracken, Paul J Brindley, R Reid Townsend, Robert Sprung, Bin Zhan, Maria-Elena Bottazzi, John M Hawdon, Yide Wong, Alex Loukas, Sergej Djuranovic, and Makedonka Mitreva
Historic clinical trial external control arm provides actionable GEN-1 efficacy estimate before a randomized trial, Xiang Yin, Ruthanna Davi, Elizabeth B Lamont, Premal H Thaker, William H Bradley, Charles A Leath 3rd, Kathleen M Moore, Khursheed Anwer, Lauren Musso, and Nicholas Borys
MethylC-analyzer: A comprehensive downstream pipeline for the analysis of genome-wide DNA methylation, Rita Jui-Hsien Lu, Pei-Yu Lin, Ming-Ren Yen, Bing-Heng Wu, and Pao-Yang Chen
Multimodal brain age estimates relate to Alzheimer disease biomarkers and cognition in early stages: A cross-sectional observational study, Peter R Millar, Brian A Gordon, Patrick H Luckett, Tammie L S Benzinger, Carlos Cruchaga, Anne M Fagan, Jason J Hassenstab, Richard J Perrin, Suzanne E Schindler, Randall J Bateman, John C Morris, Beau M Ances, and et al.
Protocol for the phase 2 EDELIFE trial investigating the efficacy and safety of intra-amniotic ER004 administration to male subjects with X-linked hypohidrotic ectodermal dysplasia, Holm Schneider, Smail Hadj-Rabia, Florian Faschingbauer, Christine Bodemer, Dorothy K Grange, Mary E Norton, Riccardo Cavalli, Gianluca Tadini, Holger Stepan, Angus Clarke, Encarna Guillén-Navarro, Sigrun Maier-Wohlfart, Athmane Bouroubi, and Florence Porte
Alcohol consumption and epigenetic age acceleration in young adults, Drew R Nannini, Lei Liu, and et al.
Intraocular pressure and medication changes associated with Xen gel stent: A systematic review of the literature, Joseph F Panarelli, Vanessa Vera, Arsham Sheybani, Nathan Radcliffe, Richard Fiscella, Brian A Francis, Oluwatosin U Smith, and Robert J Noecker
Olutasidenib (FT-2102) in patients with relapsed or refractory IDH1-mutant glioma: A multicenter, open-label, phase Ib/II trial, Macarena I de la Fuente, Brian A Van Tine, and et al.
Individual differences in naturalistic learning link negative emotionality to the development of anxiety, William J Villano, Noah I Kraus, Travis R Reneau, Brittany A Jaso, A Ross Otto, and Aaron S Heller
Preclinical studies in Krabbe disease: A model for the investigation of novel combination therapies for lysosomal storage diseases, Gregory Heller, Allison M Bradbury, Mark S Sands, and Ernesto R Bongarzone
Arginine methylation of the PGC-1α C-terminus is temperature-dependent, Meryl Mendoza, Mariel Mendoza, Tiffany Lubrino, Sidney Briski, Immaculeta Osuji, Janielle Cuala, Brendan Ly, Ivan Ocegueda, Harvey Peralta, Benjamin A. Garcia, and Cecilia I. Zurita-Lopez
Association of state insurance mandates for fertility treatment with multiple embryo transfer after preimplantation genetic testing for aneuploidy, Bronwyn S Bedrick, Katelin B Nickel, Joan K Riley, Tarun Jain, and Emily S Jungheim
Effect of a MUC5AC antibody (NPC-1C) administered with second-line gemcitabine and nab-paclitaxel on the survival of patients with advanced pancreatic ductal adenocarcinoma: A randomized clinical trial, Brandon M Huffman, Andrea Wang-Gillam, and et al.
Large variations in the prices of urologic procedures at academic medical centers 1 year after implementation of the Price Transparency Final Rule, Zeynep G Gul, Danielle R Sharbaugh, Cailey J Guercio, Daniel L Pelzman, Cameron A Jones, Emily C Hacker, Vivian I Anyaeche, Levi Bowers, Ashti M Shah, Michael G Stencel, Jonathan G Yabes, Bruce L Jacobs, and Benjamin J Davies