Open access journal articles published by WashU Medicine faculty in 2020 to the current year.

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Submissions from 2026

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PhenoFit: A framework for determining computable phenotyping algorithm fitness for purpose and reuse, Laura K Wiley, Luke V Rasmussen, Rebecca T Levinson, Jennnifer Malinowski, Sheila M Manemann, Melissa P Wilson, Martin Chapman, Jennifer A Pacheco, Theresa L Walunas, Justin B Starren, Suzette J Bielinski, and Rachel L Richesson

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Plasma ceramides levels in severe COVID-19 disease: Correlations with survival, Tri Pham, Andrea M Heredia Castillo, Andrew Atkinson, Linda R Peterson, and M Cristina Vazquez Guillamet

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Risk factors for anticoagulant-related bleeding in cancer: Traditional and cancer-specific factors, Alexa Loncharich, Brian F Gage, Suhong Luo, Martin Schoen, Amber Afzal, Amir Mahmoud, Kenneth Carson, Su-Hsin Chang, Yan Yan, and Kristen M Sanfilippo

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Risk factors for complication and reoperation in the treatment of discoid lateral meniscus in children and adolescents: A multicenter study, Suzanna Ohlsen, Jeffrey J Nepple, and et al.

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SKIDA1 sustains MLL::ENL-expressing hematopoietic progenitors during neonatal stages and promotes B-lineage priming, Jonny Mendoza-Castrejon, Wei Yang, Elisabeth Denby, Rohini Muthukumar, Emily B Casey, Riddhi M Patel, Sarah K Tasian, and Jeffrey A Magee

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The Sport Publication Observational Research Tool (SPORT): An objective tool to score the methodological quality of observational clinical sports medicine research, Andrew W Kuhn, Paul M Inclan, Ameer A Haider, Michele N Christy, Robert Brophy, Matthew Smith, Matthew J Matava, and et al.

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Ultrasound applications in the treatment of major depressive disorder: A systematic review of techniques and therapeutic potentials in clinical trials and animal model studies, Gansheng Tan, Hong Chen, and Eric C Leuthardt

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Human chorionic gonadotropin decreases cerebral cystic encephalomalacia and parvalbumin interneuron degeneration in a pro-inflammatory model of mouse neonatal hypoxia-ischemia, Benjamin Miller, Alexander Crider, Bhooma Aravamuthan, and Rafael Galindo

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Sequential platinum and PARP Inhibition enhances PD1 immunotherapy efficacy in murine Brca2 mutated pancreatic cancer, John C McVey, Max M Wattenberg, Heather Coho, Kayjana Infante, Kelly Markowitz, Devora Delman, Cynthia Clendenin, Emma E Furth, Rashmi Tondon, Ben Z Stanger, Robert H Vonderheide, Kim A Reiss, and Gregory L Beatty

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Defining the heterogeneous molecular landscape of lung cancer cell responses to epigenetic inhibition, Chuwei Lin, Catherine M Sniezek, Christopher D McGann, Rashmi Karki, Ross M Giglio, Benjamin A Garcia, José L McFaline-Figueroa, and Devin K Schweppe

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Mast cells promote pathology and susceptibility in tuberculosis, Ananya Gupta, Vibha Taneja, Javier Rangel-Moreno, Nilofer Naqvi, Abhimanyu, Yun Tao, Mushtaq Ahmed, Kuldeep Singh Chauhan, Daniela Trejo-Ponce de Leon, Gustavo Ramírez-Martínez, Luis Jiménez-Alvarez, Cesar Luna-Rivero, Joaquin Zuniga, Deepak Kaushal, and Shabaana A Khader

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The effects of ovine-derived reinforced tissue matrix surrounding silicone-based implants in a rat prepectoral reconstruction model, Sai L Pinni, Cameron Martin, Nicholas Fadell, Xiaochao Xia, Evan Marsh, Lauren Schellhardt, Xiaowei Li, Matthew D Wood, and Justin M Sacks

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Ablation of CD38 in multiple myeloma cells leads to an aggressive phenotype in a mouse xenograft model, Michael R Dyer, Alex Zheleznyak, Erin N Teubner, Julie L Prior, Brad Manion, Zhenghan Jing, Amit K Sharma, Junwei Du, Rui Tang, Mark A Fiala, John F DiPersio, Deborah Veis, Julie O'Neal, Mikhail Y Berezin, and Monica Shokeen

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Biomarkers of response to neoadjuvant palbociclib plus anastrozole in endocrine-resistant estrogen receptor-positive/HER2-negative breast cancer: A phase 2 trial, Tim Kong, Alex Mabry, Maureen Highkin, Jeremy Hoog, Zhanfang Guo, Adrian Gonzales-Gonzales, Shana Thomas, Yingduo Song, Feng Gao, Mateusz Opyrchal, Lindsay Peterson, Foluso Ademuyiwa, Julie Margenthaler, Rebecca Aft, Katherine Glover-Collins, Leslie Nehring, Yu Tao, Souzan Sanati, Ian S Hagemann, Fouad Boulos, Li Ding, Stephen T Oh, Ron Bose, Jason D Weber, Jingqin Luo, Cynthia X Ma, and et al.

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Distinct contributions of Etv2+ and Flk1+ progenitors to endothelial, hematopoietic, and cardiac lineages, Dereck Alleyne, Minseo Kim, Jun Wu, Yoojung Kwon, Ye-Ram Kim, Ashraf Ul Kabir, Matthew Ishahak, Jeffrey R Millman, Changxu Fan, Hyung Joo Lee, Karen Krchma, Xiaoyun Xing, Kory Lavine, Ting Wang, and Kyunghee Choi

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Dual roles of TRPV2 in the innate immune response to cytosolic DNA: Arresting dormant and boosting activated STING, Chen Cheng, Hsiang-Ting Lu, Shan Li, and Zhongsheng You

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Inducible deletion of DGAT1 and 2 from microglia exacerbates neurodegeneration and endolysosomal lipid accumulation in male PS19 mice, G Travis Tabor, Alexandra Litvinchuk, Yun Chen, Austin Allison, Carisa Zeng, Hao Hu, Peter B Lin, Prabal Sharma, Samira Parhizkar, Sihui Song, Xin Bao, Abhirami K Iyer, Shih Feng You, Javier Remolina Serrano, Melissa Manis, Emily Franke, Anil G Cashikar, Carla M Yuede, Celeste M Karch, Eric J Huang, Maxim Artyomov, Jason D Ulrich, David M Holtzman, and et al.

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MyD88 signaling in myeloid cells induces gastrointestinal tract injury and systemic inflammation after West Nile virus infection, Shih-Ching Lin, Fang R Zhao, Matthias Mack, Gabriel Mbalaviele, and Michael S Diamond

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Redefining the role of chaperones for Dot/Icm T4BSS-mediated substrate translocation by Legionella pneumophila, Sukhithasri Vijayrajratnam, Ahmet Hasanovic, and Joseph P Vogel

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Routine admission urinalysis has low clinical utility in psychiatric hospitalizations, Tri Pham, Devanshi Patel, Ana Berce, Alice Bewley, and Sena Sayood

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Nutrition assistance programs and pediatric weight outcomes: A systematic review, Dan Ferris, Genevieve Davison, Tyler Frank, Amanda Gilbert, Fanice Thomas, Sydney Rothman, Kim Lipsey, and Sarah Moreland-Russell

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Creative arts to enhance cervical cancer awareness using art-based messages from a Nigerian crowdsourcing open call: Qualitative thematic analysis, Abdulhammed O Babatunde, Olufunto A Olusanya, Peter Kalulu, Temitope Ojo, Onyekachukwu Anikamadu, Juliet Iwelunmor, and et al.

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Two axes of white matter development, Audrey C Luo, Deanna M Barch, and et al.

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Phase 1b/2 study of BMS-813160, a CCR2/5 dual antagonist, in combination with chemotherapy or nivolumab in patients with advanced pancreatic or colorectal cancer, Dung T Le, Nikolaos A Trikalinos, and et al.

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Africa's digital health revolution: The digital fit-viability model to move from innovation to scaled implementation, Afra Jiwa, Antony Ngatia, Karim Benali, Niclas Boehmer, Sangu Delle, Patrick Emedom-Nnamdi, Chris Opoku Fofie, Christine M O'Brien, Tobi Olatunji, Kate Obayabgona, Milind Tambe, Richard Ribon Fletcher, Adeline Adwoa Boatin, and Bethany Hedt-Gauthier

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Mapping the transcriptional regulatory network of a fungal pathogen by exploiting transcription factor perturbation, Dhoha Abid, Holly Brown, Chase Mateusiak, Tamara L Doering, and Michael R Brent

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A chemogenetic approach for temporal and cell-specific activation of endogenous GPCRs in vivo, Gwendolyn Shingles, Qianqian Pang, Jian Weng, Ryan Singer, Waleed Babar, Jiaqi Shen, Luis Vazquez-Rivera, Yao Chen, Peng Li, and Wenjing Wang

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Differential virulence and immune recognition of Klebsiella pneumoniae O-antigen subtypes O2α and O2β, Paeton L Wantuch, Lloyd S Robinson, Cory J Knoot, Christian M Harding, and David A Rosen

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Induction of moderate DNA damage enhances megakaryopoiesis and platelet production, Virginia Camacho, Luis Francisco Zirnberger Batista, and et al.

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Matched unrelated vs haploidentical donor hematopoietic cell transplantation using posttransplant cyclophosphamide, Dipenkumar Modi, Ramzi Abboud, and et al.

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New comorbidity index associated with survival after chimeric antigen receptor T-cell therapy for large B-cell lymphoma, Uri Greenbaum, Amanda Cashen, and et al.

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The computationally designed TRI2-2 miniprotein inhibitor protects against multiple SARS-CoV-2 Omicron variants, Jimin Lee, James Brett Case, Young-Jun Park, Rashmi Ravichandran, Daniel Asarnow, M Alejandra Tortorici, Jack T Brown, Shilpa Sanapala, Lauren Carter, David Baker, Michael S Diamond, and David Veesler

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Daily locomotor activity declines with tumor growth and disease progression in glioblastoma, Maria F Gonzalez-Aponte, Sofia V Salvatore, Anna R. Damato, Ruth Gn Katumba, Grayson R. Talcott, Omar H. Butt, Jian L. Campian, Jingqin Luo, Joshua B. Rubin, Olivia J. Walch, and Erik D. Herzog

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The Yeh pilus adhesin is equipped with an α-helical flap motif, which contributes to pectin adherence, Kevin O Tamadonfar, Roger D Klein, Edward D B Lopatto, Maxwell I Zimmerman, Philippe N Azimzadeh, Denise A Sanick, Justin R Porter, Jesus Bazan Villicana, Jerome S Pinkner, Bo Huey Chiang, Nathaniel C Gualberto, Karen W Dodson, Michael L Patnode, George M H et al., Gregory R Bowman, and Scott J Hultgren

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Antecedent enhancer activity predicts future susceptibility to seizures in mice, Benjamin D Boros, Mariam A Gachechiladze, Juanru Guo, Dylan A Galloway, Shayna M Mueller, Mark Shabsovich, Allen Yen, Xuhua Chen, Alexander J Cammack, Tao Shen, Robi D Mitra, Joseph D Dougherty, and Timothy M Miller

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Characterization of novel sigma receptor ligands derived from multicomponent reactions as efficacious treatments for neuropathic pain, Ryosuke Shinouchi, Bengisu Turgutalp, Rohini S Ople, Shainnel O Eans, Ashai K Williams, Haylee R Hammond, Andras Varadi, Rebecca Notis Dardashti, Susruta Majumdar, and Jay P McLaughlin

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Costs and cost-effectiveness of a culturally adapted diabetes self-management and education program for Marshallese adults, Tzeyu L Michaud, Daniel Lamprecht-Carson, Su-Hsin Chang, Clare C Brown, Jennifer A Andersen, James P Selig, Philmar Mendoza Kabua, and Pearl McElfish

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Renal PIEZO2 is an essential regulator of renin, Rose Z Hill, Jeffrey H Miner, and et al.

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Assessing the effects of eHealth literacy and the Area Deprivation Index on barriers to electronic patient portal use for orthopedic surgery: Cross-sectional observational study, Audrey Lynn Litvak, Nicholas Lin, Kelly Hynes, Jason Strelzow, and Jeffrey G Stepan

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Durability of the benefit of vagus nerve stimulation in markedly treatment-resistant major depression: A RECOVER trial report, Charles R Conway, Christopher L Kriedt, Charles F Zorumski, Hunter Brown, and et al.

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Mass spectrometry footprinting reveals how kinetic stabilizers counteract transthyretin dynamics altered by pathogenic mutations, Francisca Pinheiro, Ravi Kant, Saketh Chemuru, Nathalia Varejão, Adrián Velázquez-Campoy, David Reverter, Irantzu Pallarès, Michael L Gross, and Salvador Ventura

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Polymer conformational entropy as the driver of complex coacervation, Tommaso Inzani, Giovanni Nava, Marco Buscaglia, Andrea Soranno, Alessandro Gori, Greta Bergamaschi, Samir Suweis, Amos Maritan, and Tommaso Bellini

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Postoperative lymph Is a proximal source of ctDNA for detection of recurrence in HPV-independent head and neck cancer, Seka Lazare, Noah Earland, Peter Harris, Ricardo Ramirez, Benjamin Wahle, Sid Puram, Doug Adkins, Wade Thorstad, Rebecca Chernock, Aadel A Chaudhuri, and et al.

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The IGVF Catalog-From genetic variation to function, Daofeng Li, Shane Liu, Wenjin Zhang, Juan F Macias-Velasco, Tianjie Liu, Sarah Cody, Lucinda Antonacci-Fulton, Ting Wang, and et al.

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What is the psychological and cognitive impact of returning Alzheimer disease dementia research results to healthy research participants? A delayed-start randomised clinical trial protocol for the WeSHARE study (Washington University study of having Alzheimer disease), Sarah M Hartz, Spondita Goswami, Amy Oliver, Alissa Evans, Sacha Jackson, Erin Linnenbringer, Krista M Moulder, John C Morris, and Jessica Mozersky

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Accurate chromatin marks peak calling with Omnipeak, Oleg Shpynov and Maxim N Artyomov

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Clinical performance of a novel point-of-care high-sensitivity cardiac troponin I assay, Alan H B Wu, Stacey L House, and et al.

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Towards a unified gating scheme for the CNBD ion channel family, Jenna L Lin and Baron Chanda

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β2 and β3a regulatory subunits can coassemble in the same BK channels, Yu Zhou, Vivian Gonzalez-Perez, Xiao-Ming Xia, Gopal S Kallure, Sandipan Chowdhury, and Christopher J Lingle

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Cumulative lifespan stress, inflammation, and racial disparities in mortality between Black and White adults, Isaiah D Spears, Aaron J Gorelik, Sara A Norton, Michael J Boudreaux, Megan W Wolk, Jayne Siudzinski, Sarah E Paul, Mary A Cox, Cynthia E Rogers, Thomas F Oltmanns, Patrick L Hill, and Ryan Bogdan

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Impaired complement regulation drives chronic lung allograft dysfunction after lung transplantation, Hrishikesh S. Kulkarni, Laneshia K. Tague, Fuyi Liao, Zhiyi Liu, Lorena Garnica, Nishanth R. Shankar, Xiaobo Wu, Dequan Zhou, Yan Tao, Victoria E. Davis, Cory T. Bernardt, Derek E. Byers, Chad A. Witt, Daniel Kreisel, John P. Atkinson, Andrew E. Gelman, and et al.

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Prospective audit and feedback by antibiotic stewardship teams to reduce antibiotic overuse at hospital discharge: A stepped-wedge cluster-randomized clinical trial, Daniel J Livorsi, Michael Joshua Hendrix, Erin Rachmiel, Jahnavi Bongu, Alice Bewley, Kevin Hsueh, and et al.

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White matter hyperintensity burden and decline in driving performance among older adults, Madhur Parihar, Yasheng Chen, Byron Xu, Semere Bekena, Ramkrishna K Singh, Yiqi Zhu, Jean-Francois Trani, Jin-Moo Lee, David B Carr, Chia-Ling Phuah, Ganesh M Babulal, and Driving Real-World In-Vehicle Evaluation System (DRIVES) Project

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Abnormalities in sensorimotor brain function are related to chronicity of low back pain, Jo Armour Smith, Rongwen Tain, Kelli G Sharp, Laura M Glynn, Linda R Van Dillen, Jesse V Jacobs, and Steven C Cramer

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A catecholamine-independent pathway controlling adaptive adipocyte lipolysis, Xiao Zhang, Sreejith S Panicker, Jordan M Bollinger, Anurag Majumdar, Rami Kheireddine, Lila F Dabill, Clara Kim, Brian Kleiboeker, Fengrui Zhang, Kristann L Magee, Adam Kepecs, Gretchen A Meyer, Irfan J Lodhi, Erica L Scheller, and et al.

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A deep learning model to guide personalized mechanical circulatory support use in cardiogenic shock patients undergoing PCI, Amit P Amin, Richard G Bach, Darren C Tsang, Weili S Zheng, Raed A Qarajeh, Emmanouil S Brilakis, and Hemant Kulkarni

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Advancing inter-brain synchrony measurement: A comparative hyperscanning study of diffuse optical tomography and functional near-infrared spectroscopy, Shuo Guan, Yuhang Li, Yingbo Geng, Dongyun Li, Qiong Xu, Peisong Niu, Dalin Yang, Adam Eggebrecht, Yingchun Zhang, and Rihui Li

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Airway management in emergency department thoracotomy: A narrative review, Aaron J Lacy, Adam Liebendorfer, Sarah M Guess, Rami S Al-Aref, Anthony P Kronfli, Rachel E Armstrong, Amelia W Maiga, Alexander Bracey, and Ryan N Barnicle

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A microenvironment-driven HLA-II-associated insulin neoantigen elicits persistent memory T cell activation in diabetes, Neetu Srivastava, Anthony N Vomund, Rongzhen Yu, Orion J Peterson, Yuqing Yang, David P Turicek, Omar Abousaway, Tiandao Li, Pamela Stone, Aisha Ansar, Rima Melhem, Bo Zhang, Chang Liu, Hao Hu, Chyi-Song Hsieh, Laura Campisi, Emil R Unanue, Ana Maria Arbelaez, Cheryl F Lichti, Xiaoxiao Wan, and et al.

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An integrated analysis of three medulloblastoma clinical trials refines risk-stratification approaches for reducing toxicity and improving survival, Kyle S Smith, Jeff M Michalski, and et al.

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An integrated view of the structure and function of the human 4D nucleome, Job Dekker, Ting Wang, Daofeng Li, and et al.

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A single-cell atlas characterizes dysregulation of the bone marrow immune microenvironment associated with outcomes in multiple myeloma, William C Pilcher, Lijun Yao, Yizhe Song, Kazuhito Sato, Julia T Wang, Reyka G Jayasinghe, Jennifer A Foltz, Mark A Fiala, Chiang I-Ling, Julie Fortier, Michael Slade, Stephen T Oh, Michael P Rettig, John F DiPersio, Shaji Kumar, Ravi Vij, Li Ding, and et al.

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A survey-based assessment of treatment preferences for distal radius fractures in participants aged 65 years and older, Zayd Al Rawi, Elizabeth Graesser, and Lindley B Wall

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Atomic models of the Toxoplasma cell invasion machinery, Jianwei Zeng, Yong Fu, Pengge Qian, Wei Huang, Qingwei Niu, Wandy L Beatty, Alan Brown, L David Sibley, and Rui Zhang

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Beyond restless sleep: A cross-sectional study of obstructive sleep apnea risk, aging biomarkers, and chronic low back pain, Khalid W Freij, Fiona Bat Agbor, Philemon Domoyeri, Kiari R Kinnie, Asia M Wiggins, Demario S Overstreet, Tammie L Quinn, Shivraj S Grewal, S Justin Thomas, Walid W Freij, Shameka L Cody, Michael A Owens, Robert E Sorge, Burel R Goodin, and Edwin N Aroke

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Characteristics and outcomes of patients with hematologic malignancies hospitalized with respiratory viral infections, Zulfiqar A Lokhandwala, Brenna Park-Egan, Ravneet Waraich, Colleen A McEvoy, Andrew P Michelson, Alice F Bewley, Lynne Strasfeld, Rachel Cook, Brandon Hayes-Lattin, Catherine L Hough, and Patrick G Lyons

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Comparison of breast and gastric HER2 immunohistochemistry (IHC) scoring criteria in the assessment of endometrial carcinoma, Rachel L Furuya, Whitney Grither, Matthew A Powell, Premal H Thaker, and et al.

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Coordinated regulation of Capping Protein by CARMIL and V-1/Myotrophin, John A Hammer and John A Cooper

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Cutibacterium adaptation to life on humans provides a potential C acnes infection biomarker, Md Shafiuddin, Wen-Chi Huang, Gabriel William Prather, Jeffrey Ryan Anton, Andrew Lawrence Martin, Sydney Brianna Sillart, Jonathan Z Tang, Michael R Vittori, Michael J Prinsen, Jessica Jane Ninneman, Chandrashekhara Manithody, Jeffrey P Henderson, Alexander W Aleem, Ma Xenia Garcia Ilagan, and William H McCoy 4th

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Defining radiological healing in perianal fistulizing Crohn's disease: A TOpClass global expert Delphi consensus, Easan Anand, Jalpa Devi, David H Ballard, Shivani Joshi, Phil Tozer, Ailsa Hart, Anna Antoniou, Parakkal Deepak, Jaap Stoker, Phillip Lung, and TOpClass collaborative authors

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Diverse misfolding mutant digestive enzymes cause chronic pancreatitis through common pathways, Steven J Wilhelm, Grace E Curry, Neel Matiwala, Jianguo Lin, Tran Quach, Mark E Lowe, Miklós Sahin-Tóth, and Xunjun K Xiao

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Epithelial-mesenchymal transition and stress adaptations underlie yttrium-90 resistance in liver cancer cell lines, Alexander Zheleznyak, Dhanusha Duraiyan, Prasanth Thunuguntla, Jessica Camacho, Shuang Wu, Jingxia Liu, Jason D Weber, Daniel L J Thorek, Benjamin S Strnad, Ryan C Fields, Matthew A Ciorba, Christine Yoon, Valerie Blanc, Nicholas Davidson, Jessica Silva-Fisher, and Christopher D Malone

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Evaluation of Mycoplasma genitalium positivity and co-infection with Chlamydia trachomatis and/or Neisseria gonorrhoeae at various care sites across the United States, Rebecca Lillis, Stacey House, and et al.

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Excellent outcomes in feasibility study of radiation-free conditioning and transplant in pediatric severe aplastic anemia, Mithra Lakshmi Narasimhan, Irem Eldem, Jeffrey J Bednarski, Ginny L Schulz, Robert J Hayashi, and Shalini Shenoy

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Focused ultrasound-enhanced nose-to-brain delivery of a therapeutic antibody in a large-animal model, Siaka Fadera, Cristian Antonio Wieczorek Villas Boas, Yimei Yue, Zhaoning Gu, Jinyun Yuan, Debolina De, Buck E Rogers, Arash Nazeri, and Hong Chen

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Foot-specific exercise intervention for forefoot deformity in individuals with type 2 diabetes and peripheral neuropathy: A randomized controlled clinical trial with 3-year follow-up, J A Zellers, K Steger-May, P K Commean, H-J Jeong, E M Bullard, M J Mueller, and M K Hastings

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Frontline aspiration versus stent retriever thrombectomy for M2 occlusions: Insights from the STAR registry, Michael Gaub, Joshua Osbun, and et al.

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Genome-wide gene-sleep interaction study identifies novel lipid loci in 732,564 participants, Raymond Noordam, Karen Schwander, Lisa de Las Fuentes, Mary F Feitosa, Anh Do, C Charles Gu, Changwei Li, Michael A Province, Dabeeru C Rao, and et al.

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Identification of distinct subtypes in immune tolerance after hematopoietic cell transplantation using the prospective ABLE1.0 pediatric study cohort, Bernard Ng, Shalini Shenoy, and et al.

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Identifying disparities in same-day surgery cancellations: Impact of race and socioeconomic factors in a pediatric health system, Nicole M Santucci, Daniel Alligood, Amanda Maytin-Hevia, Danyi Wang, Kelly Chilson, Jesse Vrecenak, Andrew Yeh, and Colin A Martin

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Infant sensory gating and a developmental cascade to autistic traits and anxiety, Rebecca F Schwarzlose

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Influence of obesity and insulin resistance with hepatic steatosis on the human plasma lipidome, Max C Petersen, Gordon I Smith, Aaron M Armando, Xiong Su, Oswald Quehenberger, Edward A Dennis, and Samuel Klein

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Intraoperative neurophysiological monitoring in full-endoscopic cervical endoscopic ULBD, Miles Hudson, Sarah Esposito, Mark M Zaki, Simon M Glynn, Osama N Kashlan, John Ogunlade, Chandan Krishna, Joshua Bakhsheshian, and Christoph P Hofstetter

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Lost before forgetting: Objective driving metrics track navigation deficits tied to preclinical Alzheimer's disease, Yiqi Zhu, Ramkrishna K Singh, Semere Bekena, David C Brown, Chen Chen, Matthew Blake, Jean-François Trani, and Ganesh M Babulal

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Mapping the genetic landscape across 14 psychiatric disorders, Andrew D. Grotzinger, Alexander S. Hatoum, Emma C. Johnson, and et al.

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Mutations in Hsp40 co-chaperone change the canonical interdomain interactions stimulating LGMDD1 myopathy, Ankan K Bhadra, Geetika Aggarwal, Anshuman Jaysingh, Daniel Chen, Jil Daw, Conrad C Weihl, and Heather L True

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Oculomics and AI: The eye as a biomarker for health span, Joy Le Yi Wong, Rajendra S Apte, and et al.

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Perceived HIV risk, barriers, and preferences for HIV testing in structurally vulnerable communities in St. Louis: A Best-Worst scaling survey, Emmanuel K Tetteh, Noelle Le Tourneau, Gregory Gross, McKenzie Swan, Tyrell Manning, Justin Cole, Katie Wolf, Lawrence Hudson-Lewis, Julia D López, Todd Combs, and Virginia R McKay

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Phase I trial of ADP-A2AFP TCR T-cell therapy in patients with advanced hepatocellular or gastric hepatoid carcinoma, Tim Meyer, Benjamin R Tan, and et al.

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PrEParing for long-acting technologies: A multistate analysis of PrEP Persistence and HIV and STI lab coverage among oral PrEP initiators in St. Louis, Missouri (2014-2021), Lindsey M Filiatreau, Rupa Patel, Kate Curoe, Ashley Underwood, Joseph Cherabie, Elvin H Geng, Aditi Ramakrishnan, Rachel Presti, and Aaloke Mody

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Steroid hormone metabolites and mammographic breast density in premenopausal women, Ghazaleh Pourali, Kayode A Matthew, Myung Sik Jeon, Chongliang Luo, Gary J Patti, Jingqin Luo, and Adetunji T Toriola

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The Cognitive-Affective Social Processing and Emotion Regulation (CASPER) model, M Catalina Camacho, Elina Deshpande, and Michael T Perino

Submissions from 2025

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EatA mediated degradation of intestinal mucus is species-specific and driven by MUC2 structural features, Sergio Trillo-Muyo, Brendan Dolan, Frida Svensson, Tim J Vickers, Liisa Arike, Maria-Jose García-Bonete, Jenny K Gustafsson, Mathias I Nielsen, Hans H Wandall, James M Fleckenstein, Gunnar C Hansson, and Sjoerd van der Post

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Membrane IL-18 identifies a human macrophage subset with distinct proteomic and functional traits, Chiara Vitale, Marco Colonna, and et al.

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Chemotherapy-induced adipo-lineage cell senescence drives bone loss, Ganesh Kumar Raut, Taylor Malachowski, Anupama Melam, Renata Ramalho-Oliveira, Taylor Holt, Xianmin Luo, Zhangting Yao, Douglas V Faget, Qihao Ren, David G DeNardo, and Sheila A Stewart

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Limited therapeutic efficacy of N-acetyl-L-leucine in a mouse model of CLN1 disease, Ewa A Ziółkowska, Nicole A Pagán Torres, Hsintsung Chen, Letitia L Williams, Elizabeth M Eultgen, Agnieszka Nowacka, Joshua T Dearborn, Hemanth R Nelvagal, Ineka T Whiteman, Frances M Platt, and Jonathan D Cooper

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Distinct populations of lung capillary endothelial cells and their functional significance, Joel James, Dan Yi, Zhiyu Dai, and et al.

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Hospital–Medicare Advantage vertical integration and cardiopulmonary care in integrated hospitals, Geronimo Bejarano, Meehir N. Dixit, Alexander P. Philips, Karen E. Joynt Maddox, Meredith B. Rosenthal, Amal Trivedi, and David J. Meyers

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Benign small bowel pneumatosis intestinalis: Report of a rare adverse effect of tirzepatide, Kenneth Newcomer, Hani Soudah, Michael Beal, and Thoi H Ngo

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Real-world outcomes of talimogene laherparepvec as salvage therapy for advanced melanoma, Melissa M Yamada, Smitha Chandrasekhar, Ted A Gooley, Rita E Chen, Coley Doolittle-Amieva, George Ansstas, Shailender Bhatia, Evan T Hall, Paul T Nghiem, Song Y Park, and David Y Chen