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Submissions from 2024

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Multi-molecular hyperspectral PRM-SRS microscopy, Wenxu Zhang, Yajuan Li, Anthony A Fung, Zhi Li, Hongje Jang, Honghao Zha, Xiaoping Chen, Fangyuan Gao, Jane Y Wu, Huaxin Sheng, Junjie Yao, Dorota Skowronska-Krawczyk, Sanjay Jain, and Lingyan Shi

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NRF2 activation in Trp53;p16-deficient mice drives oral squamous cell carcinoma, Samera H Hamad, Rani S Sellers, Nathan Wamsley, Paul Zolkind, Travis P Schrank, Michael B Major, and Bernard E Weissman

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Impact of palliative care utilization among kidney cancer patients in US hospitals: A national-scale analysis, Rushin Patel, Mrunal Patel, Darshil Patel, Chieh Yang, Afoma Onyechi, Jessica Ohemeng-Dapaah, Zalak Patel, and Safia Shaikh

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Multimodal neuro-nanotechnology: Challenging the existing paradigm in glioblastoma therapy, Sergej Kudruk, Connor M Forsyth, Michelle Z Dion, Jenny K Hedlund Orbeck, Jingqin Luo, Robyn S Klein, Albert H Kim, Amy B Heimberger, Chad A Mirkin, Alexander H Stegh, and Natalie Artzi

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A digital intervention to promote self-management self-efficacy among community-dwelling individuals with stroke: Pilot randomized controlled trial, Zhaoying Li, Yating Lei, Quoc Bui, Olivia DePaul, Ginger E Nicol, David C Mohr, Sunghoon I Lee, Mandy W M Fong, Christopher L Metts, Stephanie E Tomazin, and Alex W K Wong

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Genetic drivers of heterogeneity in type 2 diabetes pathophysiology, Ken Suzuki, Ping An, Adam E. Locke, Michael A. Province, and et al.

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Description of cryptococcosis following SARS-COV-2 infection: A disease survey through the Mycosis Study Group Education and Research Consortium (MSG-19), Jeremey Walker, Andrej Spec, Adriana M Rauseo, and et al.

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High resolution spatial profiling of kidney injury and repair using RNA hybridization-based in situ sequencing, Haojia Wu, Eryn E Dixon, Qiao Xuanyuan, Juanru Guo, Yasuhiro Yoshimura, Chitnis Debashish, Anezka Niesnerova, Hao Xu, Morgane Rouault, and Benjamin D Humphreys

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Virtual, augmented, and mixed reality applications for surgical rehearsal, operative execution, and patient education in spine surgery: A scoping review, Tim Bui, Miguel A Ruiz-Cardozo, Harsh S Dave, Karma Barot, Michael Ryan Kann, Karan Joseph, Sofia Lopez-Alviar, Gabriel Trevino, Samuel Brehm, Alexander T Yahanda, and Camilo A Molina

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Androgen exposure impairs neutrophil maturation and function within the infected kidney, Teri N Hreha, Christina A Collins, Elisabeth B Cole, Rachel J Jin, and David A Hunstad

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Secretory leukocyte protease inhibitor protects against severe urinary tract infection in mice, Anne L Rosen, Michael A Lint, Dayne H Voelker, Nicole M Gilbert, Christopher P Tomera, Jesús Santiago-Borges, Meghan A Wallace, Thomas J Hannan, Carey-Ann D Burnham, Scott J Hultgren, and Andrew L Kau

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Yersiniabactin is a quorum-sensing autoinducer and siderophore in uropathogenic Escherichia coli, James R Heffernan, John A Wildenthal, Hung Tran, George L Katumba, William H McCoy, and Jeffrey P Henderson

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A general computational design strategy for stabilizing viral class I fusion proteins, Karen J Gonzalez, Jiachen Huang, Miria F Criado, Avik Banerjee, Stephen M Tompkins, Jarrod J Mousa, and Eva-Maria Strauch

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Blinatumomab consolidation post-autologous stem cell transplantation in patients with diffuse large B-cell lymphoma, Armin Ghobadi, Nicole C Foley, Jared Cohen, Michael P Rettig, Amanda F Cashen, Leah Gehrs, Stephanie Christ, Emily Street, Nicholas Wallace, Julie Ritchey, Neha Mehta-Shah, Peter Westervelt, Todd A Fehniger, Brad Kahl, Nancy L Bartlett, and John F DiPersio

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Connexin43 in mesenchymal lineage cells regulates body adiposity and energy metabolism in mice, Seung-Yon Lee, Francesca Fontana, Toshifumi Sugatani, Ignacio Portales Castillo, Giulia Leanza, Ariella Coler-Reilly, and Roberto Civitelli

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DNA hypomethylation ameliorates erosive inflammatory arthritis by modulating interferon regulatory factor-8, Gaurav Swarnkar, Nicholas P Semenkovich, Manoj Arra, Dorothy K Mims, Syeda Kanwal Naqvi, Timothy Peterson, Gabriel Mbalaviele, Chia-Lung Wu, and Yousef Abu-Amer

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Dynamic changes in the mouse hepatic lipidome following warm ischemia reperfusion injury, Kim H H Liss, Muhammad Mousa, Shria Bucha, Andrew Lutkewitte, Jeremy Allegood, L Ashley Cowart, and Brian N Finck

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Inadequate prophylaxis in patients with trauma: Anti-Xa-guided enoxaparin dosing management in critically ill patients with trauma, Grace Martin Niziolek, Lauren Mangan, Cassidi Weaver, Vanessa Prendergast, Raymond Lamore, Megan Zielke, and Niels D Martin

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Lysosome-related organelles contain an expansion compartment that mediates delivery of zinc transporters to promote homeostasis, Adelita D Mendoza, Nicholas Dietrich, Chieh-Hsiang Tan, Daniel Herrera, Jennysue Kasiah, Zachary Payne, Ciro Cubillas, Daniel L Schneider, and Kerry Kornfeld

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Outcomes of marginal zone lymphoma treated with ibrutinib in the first-line setting in the United States: A real-world analysis, Narendranath Epperla, Qiuhong Zhao, Tamara Moyo, Marcus P Watkins, Montreh Tavakkoli, Celeste Bello, Pallawi Torka, Nishitha Reddy, Colin Thomas, Kaitlin Annunzio, Beth Christian, Stefan K Barta, Geoffrey Shouse, Adam J Olszewski, and Nancy L Bartlett

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Circuit-based intervention corrects excessive dentate gyrus output in the fragile X mouse model, Pan-Yue Deng, Ajeet Kumar, Valeria Cavalli, and Vitaly A Klyachko

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Predicting proximal tubule failed repair drivers through regularized regression analysis of single cell multiomic sequencing, Nicolas Ledru, Parker C Wilson, Yoshiharu Muto, Yasuhiro Yoshimura, Haojia Wu, Dian Li, Amish Asthana, Stefan G Tullius, Sushrut S Waikar, Giuseppe Orlando, and Benjamin D Humphreys

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ARID2 mutations may relay a distinct subset of cutaneous melanoma patients with different outcomes, Favour A Akinjiyan, George Nassief, Jordan Phillipps, Tolulope Adeyelu, Andrew Elliott, Farah Abdulla, Alice Y Zhou, George Souroullas, Kevin B Kim, Ari Vanderwalde, Soo J Park, and George Ansstas

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A novel theta-controlled vibrotactile brain-computer interface to treat chronic pain: A pilot study, Phillip Demarest, Nabi Rustamov, James Swift, Tao Xie, Markus Adamek, Hohyun Cho, Elizabeth Wilson, Zhuangyu Han, Alexander Belsten, Nicholas Luczak, Peter Brunner, Simon Haroutounian, and Eric C Leuthardt

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The effect of breastfeeding practices of undernourished mothers in rural Sierra Leone on infant growth and mortality, Aminata Shamit Koroma, Kevin B Stephenson, Per O Iversen, Mark J Manary, and David Taylor Hendrixson

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SRF-deficient astrocytes provide neuroprotection in mouse models of excitotoxicity and neurodegeneration, Surya Chandra Rao Thumu, Monika Jain, Sumitha Soman, Soumen Das, Vijaya Verma, Arnab Nandi, David H Gutmann, Balaji Jayaprakash, Deepak Nair, James P Clement, Swananda Marathe, and Narendrakumar Ramanan

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Eosinophils restrain humoral alloimmunity after lung transplantation, Zhongcheng Mei, Yuriko Terada, Yuhei Yokoyama, Andrew E. Gelman, Daniel Kreisel, and et al.

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Immunoglobulin replacement products protect against SARS-CoV-2 infection in vivo despite poor neutralizing activity, Ofer Zimmerman, Alexa Michelle Altman Doss, Baoling Ying, Chieh-Yu Liang, Samantha R. Mackin, Hannah G. Davis-Adams, Lucas J. Adams, Laura A. VanBlargan, Rita E. Chen, Suzanne M. Scheaffer, Pritesh Desai, Saravanan Raju, Tarisa L. Mantia, Caitlin C. O'Shaughnessy, Jennifer Marie Monroy, H. James Wedner, Christopher J. Rigell, Andrew L. Kau, Tiffany Biason Dy, Zhen Ren, Jackson S. Turner, Jane A. O'Halloran, Rachel M. Presti, Peggy L. Kendall, Daved H. Fremont, Ali H. Ellebedy, and Michael S Diamond

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Persistent mucus plugs in proximal airways are consequential for airflow limitation in asthma, Brendan K. Huang, Kaharu Sumino, and et al.

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GenomeMUSter mouse genetic variation service enables multitrait, multipopulation data integration and analysis, Robyn L Ball, Alexander S Hatoum, Arpana Agrawal, and et al.

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How sex hormones affect migraine: An interdisciplinary preclinical research panel review, Frederick Godley III, John Meitzen, Hadas Nahman-Averbuch, Mary Angela O'Neal, David Yeomans, Nanette Santoro, Nina Riggins, and Lars Edvinsson

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A Cre-dependent reporter mouse for quantitative real-time imaging of protein kinase A activity dynamics, Elizabeth I Tilden, Aditi Maduskar, Anna Oldenborg, Bernardo L Sabatini, and Yao Chen

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A mouse model to distinguish NLRP6-mediated inflammasome-dependent and -independent functions, Runzhi Li, Yang Zan, Decai Wang, Xuequn Chen, Anmin Wang, Haoyuan Tan, Guorong Zhang, Siyuan Ding, Chen Shen, Hao Wu, and Shu Zhu

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Chimeric antigen receptor macrophages target and resorb amyloid plaques, Alexander B. Kim, Qingli Xiao, Ping Yan, Qiuyun Pan, Gaurav Pandey, Susie Grathwohl, Ernesto Gonzales, Isabella Xu, Yoonho Cho, Hans Haecker, Slava Epelman, Abhinav Diwan, Jin-Moo Lee, and Carl J DeSelm

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Streamlined identification of clinically and functionally relevant genetic regulators of lower-tract urogenital development, Meade Haller, Yan Yin, Gabe Haller, Tian Li, Qiufang Li, Laura E Lamb, and Liang Ma

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Utilization of augmented reality head-mounted display for the surgical management of thoracolumbar spinal trauma, Michael Ryan Kann, Miguel A Ruiz-Cardozo, Samuel Brehm, Tim Bui, Karan Joseph, Karma Barot, Gabriel Trevino, Abigail Carey-Ewend, Som P Singh, Matthew De La Paz, Ahmed Hanafy, Michael Olufawo, Rujvee P Patel, Alexander T Yahanda, Alexander Perdomo-Pantoja, Magalie Cadieux, Brenton Pennicooke, Camilo A Molina, and et al.

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Aducanumab anti-amyloid immunotherapy induces sustained microglial and immune alterations, Mika P Cadiz, Katelin A Gibson, Kennedi T Todd, David G Nascari, Nashali Massa, Meredith T Lilley, Kimberly C Olney, Md Mamun Al-Amin, Hong Jiang, David M Holtzman, and John D Fryer

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HIV-associated gut microbial alterations are dependent on host and geographic context, Muntsa Rocafort, Guoyan Zhao, Scott A Handley, and et al.

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Immune response to SARS-CoV-2 variants after immunization with different vaccines in Mexico, Erika Garay, Sean P J Whelan, Rebecca M DuBois, Sara M O'Rourke, Angel Eduardo Salgado-Escobar, José Esteban Muñoz-Medina, Carlos F Arias, and Susana López

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Major adverse kidney events in pediatric continuous kidney replacement therapy, Dana Y Fuhrman, Tara M Neumayr, and et al.

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Viral DNAemia and DNA virus seropositivity and mortality in pediatric sepsis, Stephanie S Cabler, Gregory A Storch, Andrew H Walton, John C Lin, and et al.

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A comparative biochemical and pathological evaluation of brain samples from knock-in murine models of Gaucher disease, Makaila L Furderer, Bahafta Berhe, Tiffany C Chen, Stephen Wincovitch, Xuntian Jiang, Nahid Tayebi, Ellen Sidransky, and Tae-Un Han

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Prenatal exposure to maternal disadvantage-related inflammatory biomarkers: Associations with neonatal white matter microstructure, Ashley F P Sanders, Brian Tirado, Nicole A Seider, Regina L Triplett, Rachel E Lean, Jeffrey J Neil, J Philip Miller, Rebecca Tillman, Tara A Smyser, Deanna M Barch, Joan L Luby, Cynthia E Rogers, Christopher D Smyser, Barbara B Warner, and et al.

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Rapid and accurate remethylation of DNA in Dnmt3a- deficient hematopoietic cells with restoration of DNMT3A activity, Yang Li, Haley J Abel, Michelle Cai, Taylor A LaValle, Tiankai Yin, Nichole M Helton, Amanda M Smith, Christopher A Miller, and Timothy J Ley

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AAPM Medical Physics Practice Guideline 14.a: Yttrium-90 microsphere radioembolization, Nathan C Busse, Nichole M Maughan, and et al.

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A fluid biomarker reveals loss of TDP-43 splicing repression in presymptomatic ALS-FTD, Katherine E Irwin, Timothy Miller, and et al.

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Associations between early trajectories of amygdala development and later school-age anxiety in two longitudinal samples, Catherine A Burrows, Kelly N Botteron, John R Pruett Jr, and et al.

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Calorie restriction reduces biomarkers of cellular senescence in humans, Zaira Aversa, Susan B Racette, and et al.

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Children's neural reactivity to maternal praise and criticism: Associations with early depressive symptoms and maternal depression, Matthew R J Vandermeer, Pan Liu, Ola Mohamed Ali, Andrew R Daoust, Marc F Joanisse, Deanna M Barch, and Elizabeth P Hayden

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Circadian immunity from bench to bedside: A practical guide, Huram Mok, Elaine Ostendorf, Alex Ganninger, Avi J. Adler, Guy Hazan, and Jeffrey A. Haspel

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Concurrent administration of serotonergic antidepressants and ozanimod in participants with relapsing multiple sclerosis from the open-label extension DAYBREAK trial, Robert T Naismith, Jeffrey A Cohen, Amit Bar-Or, Giancarlo Comi, Krzysztof W Selmaj, Hans-Peter Hartung, James K Sheffield, Anthony Krakovich, Daniel Tatosian, Chun-Yen Cheng, Jennifer Reardon, Vadim Khaychuk, Jon V Riolo, Diego Silva, and Bruce Ac Cree

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Core requirements of frailty screening in the emergency department: An international Delphi consensus study, Elizabeth Moloney, Christopher R Carpenter, and et al.

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COVID-19 vaccine perspective from adolescents' lens in the US, Meher Garg, Arnav A. Nagrecha, Ruchi Gupta, and Makeba Williams

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Creation of a national emergency medicine medical education journal club, Jessica Pelletier, James Ahn, Andrew Golden, Caroline Astemborski, Michelle D. Lall, Albert Kim, and Sara Dimeo

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Current understanding of the Alzheimer's disease-associated microbiome and therapeutic strategies, Dong-Oh Seo and David M Holtzman

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Disease characteristics, treatments, and outcomes of patients with pulmonary arterial hypertension treated with selexipag in real-world settings from the SPHERE registry (SelexiPag: tHe usErs dRug rEgistry), Vallerie McLaughlin, Harrison W Farber, Kristin B Highland, Anna R Hemnes, Murali M Chakinala, Kelly M Chin, Michelle Han, Michelle Cho, Tobore Tobore, Mohammad Rahman, and Nick H Kim

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Epidemiology and preventability of hospital-onset bacteremia and fungemia in 2 hospitals in India, Sumanth Gandra, Dorothy Sinclair, Dustin Stwalley, Jacaranda van Rheenen, David K Warren, and et al.

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Feasibility of interleukin-6 receptor blockade in cardiac antibody-mediated rejection, April A Pottebaum, Spenser E. January, Chang Liu, Steven Lavine, Joel D. Schilling, and Kory J. Lavine

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Functional network disorganization and cognitive decline following fractionated whole-brain radiation in mice, Benjamin A. Seitzman, Francisco J. Reynoso, Timothy J. Mitchell, Annie R. Bice, Anmol Jarang, Xiaodan Wang, Cedric Mpoy, Lori Strong, Buck E. Rogers, Carla M. Yuede, Joshua B. Rubin, Stephanie M. Perkins, and Adam Q. Bauer

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High-dimensional quantile mediation analysis with application to a birth cohort study of mother-newborn pairs, Haixiang Zhang, Xiumei Hong, Yinan Zheng, Lifang Hou, Cheng Zheng, Xiaobin Wang, and Lei Liu

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Legionella pneumophila usurps host cell lipids for vacuole expansion and bacterial growth, Soma Ghosh, Saumya Bandyopadhyay, Danielle M. Smith, Sangeeta Adak, Clay F. Semenkovich, Laszlo Nagy, Michael J. Wolfgang, and Tamara J. O'Connor

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Longitudinal predictors of health-related quality of life in isolated dystonia, Johanna Junker, Joel S Perlmutter, and et al.

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Machine learning-derived baseline visual field patterns predict future glaucoma onset in the Ocular Hypertension Treatment Study, Rishabh K Singh, Sophie Smith, John Fingert, Mae Gordon, Michael Kass, Todd Scheetz, Ayellet V Segrè, Janey Wiggs, Tobias Elze, and Nazlee Zebardast

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MouseVUER: Video based open-source system for laboratory mouse home-cage monitoring, Ghadi Salem, Niall Cope, Marcial Garmendia, Alex Pu, Abhishek Somenhalli, Jonathan Krynitsky, Noah Cubert, Thomas Jones, George Dold, Anthony Fletcher, Alexxai Kravitz, Thomas Pohida, and John Dennis

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Mucosal boosting enhances vaccine protection against SARS-CoV-2 in macaques, Katherine McMahan, Adrianus C M Boon, and et al.

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Multiomic profiling reveals metabolic alterations mediating aberrant platelet activity and inflammation in myeloproliferative neoplasms, Fan He, Angelo Ba Laranjeira, Tim Kong, Shuyang Lin, Katrina J. Ashworth, Alice Liu, Nina M. Lasky, Daniel Ac Fisher, Maggie J. Cox, Mary C. Fulbright, Lilian Antunes-Heck, LaYow Yu, Molly Brakhane, Bei Gao, Stephen M. Sykes, Angelo D'Alessandro, Jorge Di Paola, and Stephen T. Oh

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Optimal approaches to analyzing functional MRI data in glioma patients, Ki Yun Park, Joshua S Shimony, Satrajit Chakrabarty, Aaron B Tanenbaum, Carl D Hacker, Kara M Donovan, Patrick H Luckett, Mikhail Milchenko, Aristeidis Sotiras, Daniel S Marcus, Eric C Leuthardt, and Abraham Z Snyder

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Outcomes of ceftriaxone compared with cefazolin or nafcillin/oxacillin for outpatient therapy for methicillin-sensitive Staphylococcus aureus bloodstream infections: Results from a large United States claims database, Yasir Hamad, Katelin B Nickel, Margaret A Olsen, and Ige A George

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Patterns of self-care decision-making and associated factors: A cross-sectional observational study, Christopher S Lee, Kenneth E Freedland, Tiny Jaarsma, Anna Strömberg, Ercole Vellone, Shayleigh Dickson Page, Heleen Westland, Sara Pettersson, Michelle van Rijn, Subhash Aryal, Andrew Belfiglio, Douglas Wiebe, and Barbara Riegel

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Primary non-function of hepatic allograft with preexisting microvesicular steatosis/foamy degeneration and mild large-droplet macrovesicular steatosis, Melissa E Limia, Xiu Li Liu, Jennifer Yu, and Kathleen Byrnes

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Public platform with 39,472 exome control samples enables association studies without genotype sharing, Mykyta Artomov, Alexander A Loboda, Maxim N Artyomov, and Mark J Daly

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Pycallingcards: An integrated environment for visualizing, analyzing, and interpreting Calling Cards data, Juanru Guo, Wenjin Zhang, Xuhua Chen, Allen Yen, Lucy Chen, Christian A Shively, Daofeng Li, Ting Wang, Joseph D Dougherty, and Robi D Mitra

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Serological assays for differentiating natural COVID-19 infection from vaccine induced immunity, Samuel M S Cheng, Gaya K Amarasinghe, and et al.

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Spatial and amplitude dynamics of neurostimulation: Insights from the acute intrahippocampal kainate seizure mouse model, Thomas J Foutz, Nicholas Rensing, Lirong Han, Dominique M Durand, and Michael Wong

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Stem cell modeling of nervous system tumors, Frank B Furnari, Corina Anastasaki, Shan Bian, Howard A Fine, Tomoyuki Koga, Lu Q Le, Fausto J Rodriguez, and David H Gutmann

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Stereotactic MR-guided on-table adaptive radiation therapy (SMART) for borderline resectable and locally advanced pancreatic cancer: A multi-center, open-label phase 2 study, Michael D Chuong, Hyun Kim, Lauren E Henke, Alex T Price, and et al.

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Structural biases in disordered proteins are prevalent in the cell, David Moses, Karina Guadalupe, Feng Yu, Eduardo Flores, Anthony R Perez, Ralph McAnelly, Nora M Shamoon, Gagandeep Kaur, Estefania Cuevas-Zepeda, Andrea D Merg, Erik W Martin, Alex S Holehouse, and Shahar Sukenik

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The Bethesda ERCP Skills Assessment Tool (BESAT) can reliably differentiate endoscopists of different experience levels, Kevin Liu, Vladimir Kushnir, and et al.

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The impact of patterns in linkage disequilibrium and sequencing quality on the imprint of balancing selection, Tristan J Hayeck, Yang Li, Timothy L Mosbruger, Jonathan P Bradfield, Adam G Gleason, George Damianos, Grace Tzun-Wen Shaw, Jamie L Duke, Laura K Conlin, Tychele N Turner, Marcelo A Fernández-Viña, Mahdi Sarmady, and Dimitri S Monos

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Basis of executive functions in fine-grained architecture of cortical and subcortical human brain networks, Moataz Assem, Sneha Shashidhara, Matthew F Glasser, and John Duncan

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Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase, Stanley C Xie, Eva S Istvan, Daniel E Goldberg, and et al.

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A quick reCAP: Discovering Cryptococcus neoformans capsule mutants, Daphne Boodwa-Ko and Tamara L Doering

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Complement receptor 1 is the human erythrocyte receptor for Plasmodium vivax erythrocyte binding protein, Seong-Kyun Lee, Cécile Crosnier, Paola Carolina Valenzuela-Leon, Brian L P Dizon, John P Atkinson, Jianbing Mu, Gavin J Wright, Eric Calvo, Karthigayan Gunalan, and Louis H Miller

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Enhancing antibody responses by multivalent antigen display on thymus-independent DNA origami scaffolds, Eike-Christian Wamhoff, James Brett Case, Shilpa Sanapala, Michael S Diamond, and et al.

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Inter- and intra-observer variability of radial-endobronchial ultrasound image interpretation for peripheral pulmonary lesions, Nathaniel Moulton, Daniel B. Abbasi, Danish Ahmad, Nikki E. Burks, Praveen Chenna, Kevin Haas, Andrea Loiselle, Essam Mekhaiel, Mayank R. Pilli, Ali Sadoughi, Brandt Lydon, Tej Patel, and Alexander C. Chen

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Analysis of anemia and iron supplementation among glioblastoma patients reveals sex-biased association between anemia and survival, Ganesh Shenoy, Becky Slagle-Webb, Chachrit Khunsriraksakul, Bhavyata Pandya Shesh, Jingqin Luo, Vladimir Khristov, Nataliya Smith, Alireza Mansouri, Brad E Zacharia, Sheldon Holder, Justin D Lathia, Jill S Barnholtz-Sloan, and James R Connor

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Dorsal hippocampus to nucleus accumbens projections drive reinforcement via activation of accumbal dynorphin neurons, Khairunisa Mohamad Ibrahim, Nicolas Massaly, Hye-Jean Yoon, Rossana Sandoval, Allie J Widman, Robert J Heuermann, Sidney Williams, William Post, Sulan Pathiranage, Tania Lintz, Azra Zec, Ashley Park, Robert W Gereau 4th, Jose A Morón, and et al.

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Reviewing the Clostridioides difficile mouse model: Insights into infection mechanisms, José L Fachi, Marco A R Vinolo, and Marco Colonna

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Association of genetic variation in COL11A1 with adolescent idiopathic scoliosis, Hao Yu, Lilian Antunes, Christina A Gurnett, and et al.

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Tempo and mode of gene expression evolution in the brain across primates, Katherine Rickelton, Trisha M Zintel, Jason Pizzollo, Emily Miller, John J Ely, Mary Ann Raghanti, William D Hopkins, Patrick R Hof, Chet C Sherwood, Amy L Bauernfeind, and Courtney C Babbitt

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GlioPredictor: A deep learning model for identification of high-risk adult IDH-mutant glioma towards adjuvant treatment planning, Shuhua Zheng, Nikhil Rammohan, Timothy Sita, P Troy Teo, Yilin Wu, Maciej Lesniak, Sean Sachdev, and Tarita O Thomas

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Adverse outcomes and an immunosuppressed endotype in septic patients with reduced IFN-γ ELISpot, Evan L. Barrios, Drew E. Del Toro, Alexandra Dram, Sandra Meszaros, Sydney Miles, Andrew H. Walton, Anne M. Drewry, Isaiah R. Turnbull, Richard S Hotchkiss, and et al.

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An orally available compound suppresses glucagon hypersecretion and normalizes hyperglycemia in type 1 diabetes, Farzad Asadi, Subhadra C. Gunawardana, Roland E. Dolle, and David W. Piston

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B cells mediate lung ischemia/reperfusion injury by recruiting classical monocytes via synergistic B cell receptor/TLR4 signaling, Khashayar Farahnak, Yun Zhu Bai, Yuhei Yokoyama, Deniz B. Morkan, Zhiyi Liu, Junedh M. Amrute, Alejandro De Filippis Falcon, Yuriko Terada, Fuyi Liao, Wenjun Li, Hailey M. Shepherd, Ramsey R. Hachem, Varun Puri, Kory J. Lavine, Andrew E. Gelman, Ankit Bharat, Daniel Kreisel, and Ruben G. Nava

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CpsA mediates infection of recruited lung myeloid cells by Mycobacterium tuberculosis, Steven J Grigsby, G V R Krishna Prasad, Joshua B Wallach, Ekansh Mittal, Fong-Fu Hsu, Dirk Schnappinger, and Jennifer A Philips

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Human whole-exome genotype data for Alzheimer's disease, Yuk Yee Leung, Carlos Cruchaga, and et al.

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Neuronal deletion of the circadian clock gene Bmal1 induces cell-autonomous dopaminergic neurodegeneration, Michael K. Kanan, Patrick W. Sheehan, Jessica N. Haines, Pedro G. Gomez, Adya Dhuler, Collin J. Nadarajah, Zachary M. Wargel, Brittany M. Freeberg, Hemanth R. Nelvagal, Mariko Izumo, Joseph S. Takahashi, Jonathan D. Cooper, Albert A. Davis, and Erik S. Musiek

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Self-renewing human naïve pluripotent stem cells dedifferentiate in 3D culture and form blastoids spontaneously, Mingyue Guo, Jinyi Wu, Chuanxin Chen, Xinggu Wang, An Gong, Wei Guan, Rowan M Karvas, Kexin Wang, Mingwei Min, Yixuan Wang, Thorold W Theunissen, Shaorong Gao, and José C R Silva

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MyPathway human epidermal growth factor receptor 2 basket study: Pertuzumab + trastuzumab treatment of a tissue-agnostic cohort of patients with human epidermal growth factor receptor 2-altered advanced solid tumors, Christopher J Sweeney, Ron Bose, and et al.

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Comprehensive workflow and its validation for simulating diffuse speckle statistics for optical blood flow measurements, Lisa Kobayashi Frisk, Manish Verma, Faruk Bešlija, Chen-Hao P Lin, Nishighanda Patil, Sumana Chetia, Jason W Trobaugh, Joseph P Culver, and Turgut Durduran