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Submissions from 2015

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IL-34 mediates acute kidney injury and worsens subsequent chronic kidney disease, Jea-Hyun Baek, Rui Zeng, Julia Weinmann-Menke, M.Todd Valerius, Yukihiro Wada, Amrenda K. Ajay, Marco Colonna, and Vicki R. Kelley

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Tuberous Sclerosis complex protein 2-independent activation of mTORC1 by human cytomegalovirus pUL38, Yadan Bai, Baoqin Xuan, Haiyan Liu, Jin Zhong, Dong Yu, and Zhikang Qian

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Long-term functional recovery after facial nerve transection and repair in the rat, Caroline A. Banks, Christopher Knox, Daniel A. Hunter, Susan E. Mackinnon, Marc H. Hohman, and Tessa A. Hadlock

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Developing a pooled job physical exposure data set from multiple independent studies: An example of a consortium study of carpal tunnel syndrome, Stephen S. Bao, Jay M. Kapellusch, Arun Garg, Barbara A. Silverstein, Carisa Harris-Adamson, Susan E. Burt, Ann Marie Dale, Bradley A. Evanoff, Frederic E. Gerr, Kurt T. Hegmann, Linda A. Merlino, Matthew S. Thiese, and David M. Rempel

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The influence of age and sex on genetic associations with adult body size and shape: A large-scale genome-wide interaction study, Llida Barata, Mary F. Feitosa, Jacek Czajkowski, Jeannette Simino, Pamela A. F. Madden, Yun Ju Sung, Andrew C. Heath, Treva K. Rice, D. C. Rao, and et al.

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Rapid-Onset Obesity with Hypothalamic Dysfunction, Hypoventilation, and Autonomic Dysregulation (ROHHAD): Exome sequencing of trios, monozygotic twins and tumours, Sarah F. Barclay, Casey M. Rand, Lauren A. Borch, Lisa Nguyen, Paul A. Gray, William T. Gibson, Richard J.A. Wilson, Paul M.K. Gordon, Zaw Aung, Elizabeth M. Berry-Kravis, Diego Ize-Ludlow, Debra E. Weese-Mayer, and N. Torben Bech-Hansen

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A participatory regional partnership approach to promote nutrition and physical activity through environmental and policy change in rural Missouri, Ellen K. Barnidge, Elizabeth A. Baker, Amy Estlund, Freda Motton, Pamela R. Hipp, and Ross C. Brownson

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Exome sequencing identifies a rare HSPG2 variant associated with familial idiopathic scoliosis, Erin E. Baschal, Cambria I. Wethey, Kandice Swindle, Robin M. Baschal, Katherine Gowan, Nelson L.S. Tang, David M. Alvarado, Gabe E. Haller, Matthew B. Dobbs, Matthew R.G. Taylor, Christina A. Gurnett, Kenneth L. Jones, and Nancy H. Miller

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In vivo creatine kinase reaction kinetics at rest and stress in type II diabetic rat heart, Adil Bashir, Andrew R. Coggan, and Robert J. Gropler

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Absolute quantification of human liver phosphorus-containing metabolites in vivo using an inhomogeneous spoiling magnetic field gradient, Adil Bashir, Robert Gropler, and Joseph Ackerman

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Mucinous adenocarcinoma of the bladder associated with long term suprapubic tube: A case report, Tyler M. Bauman, Theodora A. Potretzke, Aaron M. Potretzke, Cary L. Siegel, and Steven B. Brandes

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Inducible nitric oxide synthase mediates DNA double strand breaks in Human T-Cell Leukemia Virus Type 1-induced leukemia/lymphoma, Hicham H. Baydoun, Mathew A. Cherian, Patrick Green, and Lee Ratner

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GPR18 controls reconstitution of mouse small intestine intraepithelial lymphocytes following bone marrow transplantation, Amy M. Becker, Derrick J. Callahan, Justin M. Richner, Jaebok Choi, John F. DiPersio, Michael S. Diamond, and Deepta Bhattacharya

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Rhoptry proteins ROP5 and ROP18 are major murine virulence factors in genetically divergent South American strains of Toxoplasma gondii, Michael S. Behnke, Asis Khan, Elvin J. Lauron, John R. Jimah, Qiuling Wang, Niraj H. Tolia, and L. David Sibley

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Genetic mapping reveals that sinefungin resistance in Toxoplasma gondii is controlled by a putative amino acid transporter locus that can be used as a negative selectable marker, Michael S. Behnke, Asis Khan, and L David Sibley

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Clinically early-stage CSPα mutation carrier exhibits remarkable terminal stage neuronal pathology with minimal evidence of synaptic loss, Bruno A. Benitez, Nigel J. Cairns, Robert E. Schmidt, John C. Morris, Joanne B. Norton, Carlos Cruchaga, and Mark S. Sands

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Plasma endotoxin core antibody concentration and linear growth are unrelated in rural Malawian children aged 2–5 years, Nicole Benzoni, Poonum Korpe, Chrissie Thakwalakwa, Ken Maleta, Kevin Stephenson, Micah Manary, and Mark Manary

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Positive testing for Neisseria gonorrhoeae and Chlamydia trachomatis and the risk of pelvic inflammatory disease in IUD users, Natalia E. Birgisson, Qiuhong Zhao, Gina M. Secura, Tessa Madden, and Jeffrey F. Peipert

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Preventing unintended pregnancy: The contraceptive CHOICE project in review, Natalia E. Birgisson, Qiuhong Zhao, Gina M. Secura, Tessa Madden, and Jeffrey F. Peipert

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Selective cognitive and psychiatric manifestations in Wolfram Syndrome, Allison N. Bischoff, Angela M. Reiersen, Anna Buttlaire, Amal Al-lozi, Tasha Doty, Bess A. Marshall, Tamara Hershey, and Washington University Wolfram Syndrome Research Group

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Ciliated hepatic foregut cyst: A report of 6 cases and a review of the English literature, Katherine C. Bishop, Carmen M. Perrino, Marianna B. Ruzinova, and Elizabeth M. Brunt

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Parent-of-origin effects of the APOB gene on adiposity in young adults, Ingrid B. Borecki, Felicia Gomez, and et al

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Intracellular FGF14 (iFGF14) is required for spontaneous and evoked firing in cerebellar Purkinje neurons and for motor coordination and balance, Marie K. Bosch, Yarimar Carrasquillo, Joseph L. Ransdell, Ajay Kanakamedala, David M. Ornitz, and Jeanne M. Nerbonne

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Behavioral, cognitive, and adaptive development in infants with autism spectrum disorder in the first 2 years of life, Kelly Botteron and et al

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MC1R gene variants and non-melanoma skin cancer: A pooled-analysis from the M-SKIP project, Anne Bowcock, Lynn Cornelius, Martha Laurin Council, and et al

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Feasibility of a randomized clinical trial for treatment of femoroacetabular impingement of the hip, Gloria N. Boye, Kerri Murray, John C. Clohisy, and Young-Jo Kim

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What's new in Spine Surgery, Keith H. Bridwell, Paul A. Anderson, Scott D. Boden, Han Jo Kim, Alexander Vaccaro, and Jeffrey C. Wang

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Low-order non-spatial effects dominate second-order spatial effects in the texture quantifier analysis of 18F-FDG-PET images, Frank J. Brooks and Perry W. Grigsby

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Factors associated with infection following anterior cruciate ligament reconstruction, Robert H. Brophy, Rick W. Wright, Laura J. Huston, Samuel K. Nwosu, the MOON Knee Group, and Kurt P. Spindler

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IARC monographs: 40 years of evaluating carcinogenic hazards to humans, Ross C. Brownson and et al.

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Pathogenesis of bone diseases: The role of immune system, Giacomina Brunetti, Giorgio Mori, Patrizia D'Amelio, and Roberto Faccio

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Comparison of the next-generation Xpert MRSA/SA BC assay and the GeneOhm StaphSR assay to routine culture for identification of Staphylococcus aureus and methicillin-resistant S. aureus in positive-blood-culture broths, Blake W. Buchan, Stephen Allen, Carey-Ann D. Burnham, Erin McElvania TeKippe, Thomas Davis, Michael Levi, Donna Mayne, Preeti Pancholi, Ryan F. Relich, Richard Thomson, and Nathan A. Ledeboer

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Dopaminergic, serotonergic, and noradrenergic deficits in Parkinson disease, Chandana Buddhala, Susan K. Loftin, Brandon M. Kuley, Nigel J. Cairns, Meghan C. Campbell, Joel S. Perlmutter, and Paul T. Kotzbauer

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Evaluating diabetes mobile applications for health literate designs and functionality, 2014, Charlene A. Caburnay, Kaitlin Graff, Jenine K. Harris, Amy McQueen, Madeleine Smith, Maggie Fairchild, and Matthew W. Kreuter

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The pancreas anatomy conditions the origin and properties of resident macrophages, Boris Calderon, Javier A. Carrero, Stephen T. Ferris, Dorothy K. Sojka, Lindsay Moore, Slava Epelman, Kenneth M. Murphy, Wayne M. Yokoyama, Gwendalyn J. Randolph, and Emil R. Unanue

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Mobility and safety issues in drivers with dementia, David B. Carr and Desmond O'Neill

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mTOR and MEK1/2 inhibition differentially modulate tumor growth and the immune microenvironment in syngeneic models of oral cavity cancer, Harrison Cash, Sujay Shah, Ellen Moore, Andria Caruso, Ravindra Uppaluri, Carter Van Waes, and Clint Allen

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Asthma is more severe in older adults, Mario Castro and et al.

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Clinical implications of having reduced mid forced expiratory flow rates (FEF25-75), independently of FEV1, in adult patients with asthma, Mario Castro and et al.

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Genomic analysis to define molecular basis of aggressiveness in a mouse model of oral cancer, Varun Chalivendra, Krishna Latha Kanchi, Michael D. Onken, Ashley E. Winkler, Elaine Mardis, and Ravindra Uppaluri

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Reduction of parathyroid hormone with vitamin D supplementation in blacks: A randomized controlled trial, Paulette D. Chandler, Foluso Agboola, Kimmie Ng, Jamil B. Scott, Bettina F. Drake, Gary G. Bennett, Andrew T. Chan, Bruce W. Hollis, Karen M. Emmons, Charles S. Fuchs, and Edward L. Giovannucci

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Effects of vitamin D supplementation on C-peptide and 25-hydroxyvitamin D concentrations at 3 and 6 months, Paulette D. Chandler, Edward L. Giovannucci, Jamil B. Scott, Gary G. Bennett, Kimmie Ng, Andrew T. Chan, Bruce W. Hollis, Nader Rifai, Karen M. Emmons, Charles S. Fuchs, and Bettina F. Drake

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Impact of vitamin D supplementation on adiposity in African-Americans, P D. Chandler, J B. Scott, B F. Drake, K Ng, A T. Chan, B W. Hollis, K M. Emmons, E L. Giovannucci, C S. Fuchs, and G G. Bennett

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A latent class analysis of risk factors for acquiring HIV among men who have sex with men: implications for implementing pre-exposure prophylaxis programs, Philip A. Chan, Jennifer Rose, Justine Maher, Stacey Benben, Kristen Pfeiffer, Alexi Almonte, Joanna Poceta, Catherine E. Oldenburg, Sharon Parker, Brandon D.L Marshall, Mickey Lally, Kenneth Mayer, Leandro Mena, Rupa Patel, and Amy S. Nunn

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Epigenetic and microRNA regulation during osteoarthritis development, Di Chen, Jie Shen, and Tianqian Hui

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Structural analysis of the synthetic Duffy Binding Protein (DBP) antigen DEKnull relevant for Plasmodium vivax malaria vaccine design, Edwin Chen, Nichole D. Salinas, Francis B. Ntumngia, John H. Adams, and Niraj H. Tolia

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Aggregate blood pressure responses to serial dietary sodium and potassium intervention: Defining responses using independent component analysis, Gengsheng Chen, Lisa de las Fuentes, Chi C. Gu, Jiang He, Dongfeng Gu, Tanika Kelly, James Hixson, Cashell Jacquish, D. C. Rao, and Treva K. Rice

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mTORC1 signaling promotes osteoblast differentiation from preosteoblasts, Jianquan Chen and Fanxin Long

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STAT1 modification improves therapeutic effects of interferons on lung cancer cells, Junjie Chen, Jialu Zhao, Lefu Chen, Nian Dong, Zhaojian Ying, Zhenzhen Cai, Dongxiang Ji, Yong Zhang, Li Dong, Yuping Li, Lei Jiang, Michael J. Holtzman, and Chengshui Chen

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Myeloid lineage skewing due to exacerbated NF-κB signaling facilitates osteopenia in Scurfy mice, T H-P Chen, G Swarnkar, G Mbalaviele, and Y Abu-Amer

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Mouse low-grade gliomas contain cancer stem cells with unique molecular and functional properties, Yi-Hsien Chen, Lucy D'Agostino McGowan, Patrick J. Cimino, Sonika Dahiya, Jeffrey R. Leonard, Da Yong Lee, and David H. Gutmann

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Focal segmental glomerulosclerosis: Molecular genetics and targeted therapies, Ying Maggie Chen and Helen Liapis

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Coenzyme Q10 restores oocyte mitochondrial function and fertility during reproductive aging, Maggie Chi, Kelle H. Moley, and et al

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Cytosolic phospholipase A 2 plays a crucial role in ROS/NO signaling during microglial activation through the lipoxygenase pathway, Dennis Y. Chuang, Agnes Simonyi, Paul T. Kotzbauer, Zezong Gu, and Grace Y. Sun

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Cytosolic phospholipase A2 plays a crucial role in ROS/NO signaling during microglial activation through the lipoxygenase pathway, Dennis Y. Chuang, Agnes Simonyi, Paul T. Kotzbauer, Zezong Gu, and Grace Y. Sun

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Albumin-associated free fatty acids induce macropinocytosis in podocytes, Jun-Jae Chung, Tobias B. Huber, Markus Gödel, George Jarad, Björn Hartleben, Christopher Kwoh, Alexander Keil, Aleksey Karpitskiy, Jiancheng Hu, Christine J. Huh, Marina Cella, Richard W. Gross, Jeffrey H. Miner, and Andrey S. Shaw

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Obesity and aerobic fitness among urban public school students in elementary, middle, and high school, B. Ruth Clark, M. Leanne White, Nathaniel K. Royer, Tamara L. Burlis, Nicholas C. DuPont, Michael Wallendorf, and Susan B. Racette

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Influence of home and school environments on specific dietary behaviors among postpartum, high-risk teens, 27 states, 2007-2009, Megan A. Clarke, Debra L. Haire-Joshu, Cynthia D. Schwarz, Rachel G. Tabak, and Corinne E. Joshu

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Exome sequencing reveals pathogenic mutations in 91 strains of mice with Mendelian disorders, Paul Cliften, Jeffrey Milbrandt, and et al

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Sickle cell disease: Wheeze or asthma?, Robyn T. Cohen, Elizabeth S. Klings, and Robert C. Strunk

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Association between dietary patterns during pregnancy and birth size measures in a diverse population in Southern US, Uriyoán Colón-Ramos, Susan B. Racette, Jody Ganiban, Thuy G. Nguyen, Mehmet Kocak, Kecia N. Carroll, Eszter Völgyi, and Frances A. Tylavsky

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Differential mechanisms of Cantú syndrome–associated gain of function mutations in the ABCC9 (SUR2) subunit of the KATP channel, Paige E. Cooper, Monica Sala-Rabanal, Sun Joo Lee, and Colin G. Nichols

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In vivo kinetic approach reveals slow SOD1 turnover in the CNS, Matthew J. Crisp, Kwasi G. Mawuenyega, Bruce W. Patterson, Naveen C. Reddy, Robert Chott, Wade K. Self, Conrad C. Weihl, Jennifer Jockel-Balsarotti, Arun S. Varadhachary, Robert C. Bucelli, Kevin E. Yarasheski, Randall J. Bateman, and Rimothy M. Miller

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Epidemiology, co-infections, and outcomes of viral pneumonia in adults an observational cohort study, Matthew P. Crotty, Shelby Meyers, Nicholas B. Hampton, Stephanie Bledsoe, David J. Ritchie, Richard S. Buller, Gregory A. Storch, Scott T. Micek, and Marin H. Kollef

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Impact of antibacterials on subsequent resistance and clinical outcomes in adult patients with viral pneumonia: An opportunity for stewardship, Matthew P. Crotty, Shelby Meyers, Nicholas Hampton, Stephanie Bledsoe, David J. Ritchie, Richard S. Buller, Gregory A. Storch, Marin H. Kollef, and Scott T. Micek

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Automatic analysis (aa): Efficient neuroimaging workflows and parallel processing using Matlab and XML, Rhodri Cusack, Alejandro Vicente-Grabovetsky, Daniel J. Mitchell, Conor J. Wild, Tibor Auer, Annika C. Linke, and Jonathan E. Peelle

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Citrulline protects Streptococcus pyogenes from acid stress using the arginine deiminase pathway and the F1Fo-ATPase, Zachary T. Cusumano and Michael G. Caparon

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The ATF6 pathway of the ER stress response contributes to enhanced viability in glioblastoma, David Y A Dadey, Vaishali Kapoor, Arpine Khudanyan, Fumihiko Urano, Albert H. Kim, Dinesh Thotala, and Dennis E. Hallahan

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Quantitative evaluation of the community research fellows training program, Lucy D'Agostino McGowan, Jewel D. Stafford, Vetta Lynn Thompson, Bethany Johnson-Javois, and Melody S. Goodman

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Comparison of automated versus traditional nerve conduction study methods for median nerve testing in a general worker population, Ann Marie Dale, Folasad Agboola, Amber Yun, Angelique Zeringue, Muhammed T. Al-Lozi, and Bradley A. Evanoff

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Responsiveness of a 1-year recall modified DASH Work module in active workers with upper extremity musculoskeletal symptoms, Ann Marie Dale, Bethany T. Gardner, Skye Buckner-Petty, Victoria Kaskutas, Jamie Strickland, and Bradley A. Evanoff

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Comparison of musculoskeletal disorder health claims between construction floor layers and a general working population, Ann Marie Dale, Daniel Ryan, Laura Welch, Margaret A. Olsen, Bryan Buchholz, and Bradley A. Evanoff

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General population job exposure matrix applied to a pooled study of prevalent carpal tunnel syndrome, Ann Marie Dale, Angelique Zeringue, Carisa Harris-Adamson, David Rempel, Stephen Bao, Matthew S. Thiese, Linda Merlino, Susan Burt, Jay Kapellusch, Arun Garg, Fred Gerr, Kurt T. Hegmann, Ellen A. Eisen, and Bradley A. Evanoff

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Oxidative stress biomarkers and incidence of postoperative atrial fibrillation in the Omega‐3 Fatty Acids for Prevention of Postoperative Atrial Fibrillation (OPERA) trial, Ralph J. Damiano, Joann Marsala, and et al

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Knocking on closed doors: Host interferons dynamically regulate blood-brain barrier function during viral infections of the central nervous system, Brian P. Daniels and Robyn S. Klein

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Trends in opioid analgesic abuse and mortality in the United States, Richard C. Dart, Hilary L. Surratt, Theodore J. Cicero, Mark W. Parrino, S Geoff Severtson, Becki Bucher-Bartelson, and Jody L. Green

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Nonverbal reasoning in preschool children: Investigating the putative risk of secondhand smoke exposure and attention-deficit/hyperactivity disorder as a mediator, Duneesha De Alwis, Mini Tandon, Rebecca Tillman, and Joan Luby

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Role of ABCA7 loss-of-function variant in Alzheimer's disease: A replication study in European–Americans, Jorge L. Del-Aguila, Maria Victoria Fernandez, Jessica Jimenez, Kathleen Black, Shengmei Ma, Yuetiva Deming, David Carrell, Ben Saef, Bill Howells, John Budde, and Carlos Cruchaga

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Lateral epicondylitis: new evidence for work relatedness, Alexis Descatha, Ann Marie Dale, Barbara A. Silverstein, Yves Roquelaure, and David Rempel

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Validation of a risk prediction tool for coronary heart disease in middle-aged women, Katerina M. De Vito, Heather J. Baer, Hank Dart, Stephanie E. Chiuve, Eric B. Rimm, and Graham A. Colditz

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Preparing for the next epidemic with basic virology, Michael S. Diamond

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Germline mutations in predisposition genes in pediatric cancer, Li Ding, Elaine R. Mardis, Richard K. Wilson, and et al

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Efficacy, safety, and survival with ruxolitinib in patients with myelofibrosis: results of a median 3-year follow-up of COMFORT-I, John F. DiPersio and et al

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A consensus-based interpretation of the benchmark evidence from South American trials: treatment of intracranial pressure trial, Michael N. Diringer and et al

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Filling in the gaps: Anticipatory control of eye movements in chronic mild traumatic brain injury, Mithun Diwakar, Deborah L. Harrington, Jun Maruta, Jamshid Ghajar, Fady El-Gabalawy, Laura Muzzatti, Maurizio Corbetta, Ming-Xiong Huang, and Roland R. Lee

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Preparedness of Ob/Gyn residents for fellowship training in gynecologic oncology, David W. Doo, Matthew Powell, Akiva Novetsky, Jeanelle Sheeder, and Saketh R. Guntupalli

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Mitochondrial dynamism and heart disease: Changing shape and shaping change, Gerald W. Dorn II

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Mammograms on-the-go—predictors of repeat visits to mobile mammography vans in St Louis, Missouri, USA: A case–control study, Bettina F. Drake, Salmafatima S. Abadin, Sarah Lyons, Su-Hsin Chang, Lauren T. Steward, Susan Kraenzle, and Melody S. Goodman

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Toxoplasma actin is required for efficient host cell invasion, Lisa L. Drewry and L. David Sibley

Risk factors for acquisition and loss of Clostridium difficile colonization in hospitalized patients, Erik R. Dubberke, Kimberly A. Reske, Sondra Seiler, Tiffany Hink, Jennie H. Kwon, and Carey-Ann D. Burnham

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Response to nodal morphogen gradient is determined by the kinetics of target gene induction, Julien Dubrulle, Benjamin M. Jordan, Laila Akhmetova, Jeffrey A. Farrell, Seok-Hyung Kim, Lilianna Solnica-Krezel, and Alexander F. Schier

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Implementing administrative evidence based practices: Lessons from the field in six local health departments across the United States, Kathleen Duggan, Kristelle Aisaka, Rachel G. Tabak, Carson Smith, Paul Erwin, and Ross C. Brownson

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Relationship between abuse and neglect in childhood and diabetes in adulthood: Differential effects by sex, national longitudinal study of adolescent health, Alexis E. Duncan, Wendy F. Auslander, Kathleen K. Bucholz, Darrell L. Hudson, Richard I. Stein, and Neil H. White

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CCR5 limits cortical viral loads during West Nile virus infection of the central nervous system, Douglas M. Durrant, Brian P. Daniels, TracyJo Pasieka, Denise Dorsey, and Robyn S. Klein

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Comparing interventions and exploring neural mechanisms of exercise in Parkinson disease: A study protocol for a randomized controlled trial, Gammon M. Earhart, Ryan P. Duncan, John L. Huang, Joel S. Perlmutter, and Kristen A. Pickett

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Kappa Opioid receptor-induced aversion requires p38 MAPK activation in VTA dopamine neurons, Jonathan M. Ehrich, Daniel I. Messinger, Cerise R. Knakal, Jamie R. Kuhar, Selena S. Schatteuer, Michael R. Bruchas, Larry S. Zweifel, Brigitte L. Kieffer, Paul E M Phillips, and Charles Chavkin

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Three-year efficacy and safety of a new 52-mg levonorgestrel-releasing intrauterine system, David L. Eisenberg, Courtney A. Schreiber, David K. Turok, Stephanie B. Teal, Carolyn L. Westhoff, Mitchell D. Creinin, and ACCESS IUS Investigators

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Emotional eating phenotype is associated with central dopamine D2 receptor binding independent of body mass index, Sarah A. Eisenstein, Allison N. Bischoff, Danuta M. Gradysa, Jo Ann V. Antenor-Dorsey, Jonathan M. Koller, Amal Al-Lozi, Marta Y. Pepino, Samuel Klein, Joel S. Perlmutter, Stephen M. Morelein, Kevin J. Black, and Tamara Hershey

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Emotional eating phenotype is associated with central dopamine D2 receptor binding independent of body mass index, Sarah A. Eisenstein, Allison N. Bischoff, Danuta M. Gredysa, Jo Ann V. Antenor-Dorsey, Jonathan M. Koller, Amal Al-Lozi, Marta Y. Pepino, Samuel Klein, Joel S. Perlmutter, Stephen M. Moerlein, Kevin J. Black, and Tamara Hershey

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Insulin, central dopamine D2 receptors, and monetary reward discounting in obesity, Sarah A. Eisenstein, Danuta M. Gredysa, Jo Ann Antenor-Dorsey, Leonard Green, Ana Maria Arbelaez, Jonathan M. Koller, Kevin J. Black, Joel S. Perlmutter, Stephen M. Moerlein, and Tamara Hershey