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Submissions from 2014

Tissue-resident natural killer (NK) cells are cell lineages distinct from thymic and conventional splenic NK cells, Dorothy K. Sojka, Beatrice Plougastel-Douglas, Liping Yang, Melissa A. Pak-Wittel, Maxim N. Artyomov, Yulia Ivanova, Chao Zhong, Julie M. Chase, Paul B. Rothman, Jenny Yu, Joan K. Riley, Jinfang Zhu, Zhigang Tian, and Wayne M. Yokoyama

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Dynamic radiographic criteria for detecting pseudarthrosis following anterior cervical arthrodesis, Kwang-Sup Song, Chaiwat Piyaskulkaew, Tapanut Chuntarapas, Jacob M. Buchowski, Han Jo Kim, Moon Soo Park, Hyun Kang, and K. Daniel Riew

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State practitioner insights into local public health challenges and opportunities in obesity prevention: A qualitative study, Katherine A. Stamatakis, Moira Lewis, Elaine C. Khoong, and Claire LaSee

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Unexpected abrupt increase in left ventricular assist device thrombosis, Randall C. Starling, Nader Moazami, Scott C. Silvestry, Gregory Ewald, Joseph G. Rogers, Carmelo A. Milano, J Eduardo Rame, Michael A. Acker, Eugene H. Blackstone, John Ehrlinger, Lucy Thuita, Maria M. Mountis, Edward G. Soltesz, Bruce W. Lytle, and Nicholas G. Smedira

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Expression of nampt in hippocampal and cortical excitatory neurons is critical for cognitive function, Liana Roberts Stein, David F. Wozniak, Joshua T. Dearborn, Shunsuke Kubota, Rajendra S. Apte, Yukitoshi Izumi, Charles F. Zorumski, and Shin-ichiro Imai

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Impact of radiation therapy on survival in patients with triple‑negative breast cancer, Lauren T. Steward, Feng Gao, Marie A. Taylor, and Julie A. Margenthaler

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Arterial spin labeling versus BOLD in direct challenge and drug-task interaction pharmacological fMRI, Stephanie B. Stewart, Jonathan M. Koller, Meghan C. Campbell, and Kevin J. Black

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Distribution and medical impact of loss-of-function variants in the Finnish founder population, Nathan O. Stitziel and et al

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Subtelomeric CTCF and cohesin binding site organization using improved subtelomere assemblies and a novel annotation pipeline, Nicholas Stong, Zhong Deng, Ravi Gupta, Sufen Hu, Shiela Paul, Amber K. Weiner, Evan E. Eichler, Tina Graves, Catrina C. Fronick, Laura Courtney, Richard K. Wilson, Paul M. Lieberman, Ramana V. Davuluri, and Harold Riethman

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Prenatal tobacco smoke exposure is associated with childhood DNA CpG methylation, Robert Strunk and et al

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Single nucleotide variants in transcription factors associate more tightly with phenotype than with gene expression, Priya Sudarsanam and Barak A. Cohen

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Mitochondrial dysfunction induces Sarm1-dependent cell death in sensory neurons, Daniel W. Summers, Aaron DiAntonio, and Jeffrey Milbrandt

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TCAB1: A potential target for diagnosis and therapy of head and neck carcinomas, Chong-kui Sun, Xiao-bo Luo, Ya-ping Gou, Ling Hu, Kun Wang, Chao Li, Zhen-ting Xiang, Ping Zhang, Xiang-li Kong, Chao-liang Zhang, Qin Yang, Jing Li, Li-ying Xiao, Yan Li, and Qian-ming Chen

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Widespread contribution of transposable elements to the innovation of gene regulatory networks, Vasavi Sundaram, Yong Cheng, Zhihai Ma, Daofeng Li, Xiaoyun Xing, Peter Edge, Michael P. Snyder, and Ting Wang

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Whole genome sequence analysis of the simulated systolic blood pressure in Genetic Analysis Workshop 18 family data: Long-term average and collapsing methods, Yun Ju Sung, Jacob Basson, and Dabeeru C. Rao

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Comparison of two methods for analysis of gene-environment interactions in longitudinal family data: The Framingham heart study, Yun Ju Sung, Jeannette Simino, Rezart Kume, Jacob Basson, Karen Schwander, and D. C. Rao

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Congenitally acquired persistent lymphocytic choriomeningitis viral infection reduces neuronal progenitor pools in the adult hippocampus and subventricular zone, Tony Sun, Michael J. Vasek, and Robyn S. Klein

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Constitutive activation of IKK2/NF-κB impairs osteogenesis and skeletal development, Gaurav Swarnkar, Kaihua Zhang, Gabriel Mbalaviele, Fanxin Long, and Yousef Abu-Amer

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Proteasome inhibitors activate autophagy involving inhibition of PI3K-Akt-mTOR pathway as an anti-oxidation defense in human RPE cells, Bingrong Tang, Jingjing Cai, Lin Sun, Yiping Li, Jia Qu, Barbara Joy Snider, and Shengzhou Wu

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Genome sequence of Escherichia coli O157:H7 strain 2886-75, associated with the first reported case of human infection in the United States, Phillip I. Tarr and et al

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The role of muscle loading on bone (re)modeling at the developing enthesis, Alexander M. Tatara, Justin H. Lipner, Rosalina Das, H. Mike Kim, Nikunj Patel, Eleni Ntouvali, Matthew J. Silva, and Stavros Thomopoulos

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Interferon regulatory factor 5-dependent immune responses in the draining lymph node protect against West Nile Virus infection, Larissa B. Thackray, Bimmi Shrestha, Justin M. Richner, Jonathan J. Miner, Amelia K. Pinto, Helen M. Lazear, and Michael Gale Jr.

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Mycobacterium ulcerans infection imported from Australia to Missouri, USA, 2012, Benjamin Stuart Thomas, Thomas C. Bailey, Julu Bhatnagar, Jana M. Ritter, Brian D. Emery, Omar W. Jassim, Ian Kerst Hornstra, and Sarah L. George

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Using written narratives in public health practice: A creative writing perspective, Tess Thompson and Matthew W. Kreuter

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Mechanistically distinct mouse models for CRX-associated retinopathy, Nicholas M. Tran, Alan Zhang, Xiaodong Zhang, Julie B. Huecker, Anne K. Hennig, and Shiming Chen

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Dysferlin mediates the cytoprotective effects of TRAF2 following myocardial ischemia reperfusion injury, Huei-Ping Tzeng, Sarah Evans, Feng Gao, Kari Chambers, Veli K. Topkara, Natarajan Sivasubramanian, Philip M. Barger, and Douglas L. Mann

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Species D human adenovirus type 9 exhibits better virus-spread ability for antitumor efficacy among alternative serotypes, Junji Uchino, David T. Curiel, and Hideyo Ugai

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Altered microglial response to Aβ plaques in APPPS1-21 mice heterozygous for TREM2, Jason D. Ulrich, Mary Beth Finn, Yaming Wang, Alice Shen, Thomas E. Mahan, Hong Jiang, Floy R. Stewart, Laura Piccio, Marco Colonna, and David M. Holtman

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Cryptococcus at work: Gene expression during human infection, Rajendra Upadhya, Maureen J. Donlin, and Jennifer K. Lodge

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CD271 is a functional and targetable marker of tumor-initiating cells in head and neck squamous cell carcinoma, Ravindra Uppaluri, James S. Lewis Jr, and et al

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Origin and consequences of the relationship between protein mean and variance, Francesco Luigi Massimo Vallania, Marc Sherman, Zane Goodwin, Ilaria Mogno, Barak Alon Cohen, and Robi David Mitra

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Listening effort and accented speech, Kristen J. Van Engen and Jonathan E. Peelle

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Speckle contrast optical tomography: A new method for deep tissue three-dimensional tomography of blood flow, Hari M. Varma, Claudia P. Valdes, Anna K. Kristoffersen, Joseph P. Culver, and Turgut Durduran

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Treatment of gram - positive infections in critically ill patients, Cristina Vazquez-Guillamet and Marin H. Kollef

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Association between the intake of alpha-linolenic acid and the risk of CHD, Mia S. Vedtofte, Marianne U. Jakobsen, Lotte Lauritzen, Eilis J. O'Reilly, Jarmo Virtamo, Paul Knekt, Graham Colditz, Göran Hallmans, Julie Buring, Lyn M. Steffen, Kimberly Robien, Eric B. Rimm, and Berit L. Heitmann

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Experimental infection of rhesus macaques and common marmosets with a European strain of West Nile virus, Babs E. Verstrepen, Zahra Fagrouch, Melanie van Heteren, Hester Buitendijk, Tom Haaksma, Niels Beenhakker, Giorgio Palu, Justin M. Richner, Michael S. Diamond, Willy M. Bogers, Luisa Barzon, Stefan Chabierski, Sebastian Ulbert, Ivanela Kondova, and Ernst J. Verschoor

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Mitochondrial pyruvate carrier 2 hypomorphism in mice leads to defects in glucose-stimulated insulin secretion, Patrick A. Vigueira, Kyle S. McCommis, George G. Schweitzer, Maria S. Remedi, Kari T. Chambers, Xiaorong Fu, William G. McDonald, Serena L. Cole, Jerry R. Colca, Rolf F. Kletzien, Shawn C. Burgess, and Brian N. Finck

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The VWFA: It's not just for words anymore, Alecia C. Vogel, Steven E. Petersen, and Bradley L. Schlaggar

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PI3Kδ inhibition by idelalisib in patients with relapsed indolent lymphoma, Nina D. Wagner-Johnston and et al

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Identification of Alternative Transcripts Encoding the Essential Murine Gammaherpesvirus Lytic Transactivator RTA, Brian S. Wakeman, L. Steven Johnson, Clinton R. Paden, Kathleen S. Gray, Herbert W. Virgin, and Samuel H. Speck

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Reactivation of multiple viruses in patients with sepsis, Andrew H. Walton, Jared T. Muenzer, David Rasche, Jonathan S. Boomer, Bryan Sato, Bernard H. Brownstein, Alexandre Pachot, Terrence L. Brooks, Elena Deych, William D. Shannon, Jonathan M. Green, Gregory A. Storch, and Richard S. Hotchkiss

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Expert recommendations for implementing change (ERIC): Protocol for a mixed methods study, Thomas J. Waltz, Byron J. Powell, Matthew J. Chinman, Jeffrey L. Smith, Monica M. Matthieu, Enola K. Proctor, Laura J. Damschroder, and JoAnn E. Kirchner

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NOD2 is dispensable for ATG16L1 deficiency-mediated resistance to urinary tract infection, Caihong Wang, Xuejun Yuan, Emly Ma, Graziella R. Mendonsa, Theo R. Plantinga, Lambertus A. Kiemeney, Sita H. Vermeulen, and Indira U. Mysorekar

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Fruits of virus discovery: New pathogens and new experimental models, David Wang

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Chromophore supply rate-limits mammalian photoreceptor dark adaptation, Jin-shan Wang, Soile Nymark, Rikard Frederiksen, Maureen E. Estevez, Susan Q. Shen, Joseph C. Corbo, M. Carter Cornwall, and Vladimir J. Kefalov

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Adjuvant-specific regulation of long-term antibody responses by ZBTB20, Yinan Wang and Deepta Bhattacharya

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Your Path to Transplant: A randomized controlled trial of a tailored computer education intervention to increase living donor kidney transplant, Amy D. Waterman, Mark L. Robbins, Andrea L. Paiva, John D. Peipert, Crystal S. Kynard-Amerson, Christina J. Goalby, LaShara A. Davis, Jessica L. Thein, Emily A. Schenk, Kari A. Baldwin, Stacy L. Skelton, Nicole R. Amoyal, and Leslie A. Brick

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Smokers’ beliefs about the tobacco control potential of “a gene for smoking”: A focus group study, Erika A. Waters, Linda Ball, Kimberly Carter, and Sarah Gehlert

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p62 is required for stem cell/progenitor retention through inhibition of IKK/NF-κB/Ccl4 signaling at the bone marrow macrophage-osteoblast niche, Marcus Watkins, Roberto Civitelli, and et al

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Distinct lysosome phenotypes influence inflammatory function in peritoneal and bone marrow-derived macrophages, Kassandra Weber and Joel D. Schilling

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Microbial community dynamics and stability during an ammonia-induced shift to syntrophic acetate oxidation, Jeffrey J. Werner, Marcelo L. Garcia, Sarah D. Perkins, Kevin E. Yarasheski, Samuel R. Smith, Brian D. Muegge, Frank J. Stadermann, Christopher M. DeRito, Christine Floss, Eugene L. Madsen, Jeffrey I. Gordon, and Largus T. Angenent

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Septic arthritis of a native knee joint due to Corynebacterium striatum, Lars F. Westblade, Farah Shams, Scott Duong, Oosman Tariq, Alan Bulbin, Dava Klirsfeld, Wei Zhen, Smita Sakaria, Bradley A. Ford, Carey-Ann D. Burnham, and Christine C. Ginnochio

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Transcriptome sequencing reveals altered long intergenic non-coding RNAs in lung cancer, Nicole M. White, Christopher R. Cabanski, Jessica M. Silva-Fisher, Ha X. Dang, Ramaswamy Govindan, and Christopher A. Maher

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Chemokines in the balance: Maintenance of homeostasis and protection at CNS barriers, Jessica L. Williams, David W. Holman, and Robyn S. Klein

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Targeting CXCR7/ACKR3 as a therapeutic strategy to promote remyelination in the adult central nervous system, Jessica L. Williams, Jigisha R. Patel, Brian P. Daniels, and Robyn S. Klein

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Clinical trial design in the era of comparative effectiveness research, Anke C. Winter and Graham A. Colditz

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Current perspectives on antibody-mediated rejection after lung transplantation, Chad A. Witt and Ramsey R. Hachem

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Data requirements for electronic surveillance of healthcare-associated infections, Keith F. Woeltje, Michael Y. Lin, Michael Klompas, Marc Oliver Wright, Gianna Zuccotti, and William E. Trick

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Long-term outcomes following a single corticosteroid injection for trigger finger, Robert D. Wojahn, Nicholas C. Foeger, Richard H. Gelberman, and Ryan P. Calfee

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An fMRI study of the influence of a history of substance abuse on working memory-related brain activation in schizophrenia, Jessica A. Wojtalik and Deanna M. Barch

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Quantitative evaluation of atlas-based highdensity diffuse optical tomography for imaging of the human visual cortex, Xue Wu, Adam T. Eggebrecht, Silvina L. Ferradal, Joseph P. Culver, and Hamid Dehghani

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Metagenomic analysis of double-stranded DNA viruses in healthy adults, Kristine M. Wylie, Kathie A. Mihindukulasuriya, Yanjiao Zhou, Erica Sodergren, Gregory A. Storch, and George M. Weinstock

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Enhancing astrocytic lysosome biogenesis facilitates Aβ clearance and attenuates amyloid plaque pathogenesis, Qingli Xiao, Ping Yan, Xiucui Ma, Haiyan Liu, Ronaldo Perez, Alec Zhu, Ernesto Gonzales, Jack M. Burchett, Dorothy R. Schuler, John R. Cirrito, Abhinav Diwan, and Jin-Moo Lee

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Alzheimer’s therapeutics targeting amyloid beta 1–42 oligomers II: Sigma-2/PGRMC1 receptors mediate Abeta 42 oligomer binding and synaptotoxicity, Jinbin Xu, Chenbo Zeng, Carlos Cruchaga, Alison Goate, Robert H. Mach, and et al

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Sterol biosynthesis is required for heat resistance but not extracellular survival in Leishmania, Wei Xu, Fong-Fu Hsu, Eda Baykal, Juyang Huang, and Kai Zhang

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Blasts-more than meets the eye: Evaluation of post-induction day 21 bone marrow in CBFB rearranged acute leukemia, Xiangdong Xu and Eric J. Duncavage

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Cell type-specific expression analysis to identify putative cellular mechanisms for neurogenetic disorders, Xiaoxiao Xu, Alan B. Wells, David R. O'Brien, Arye Nehorai, and Joseph D. Dougherty

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Rho1 regulates adherens junction remodeling by promoting recycling endosome formation through activation of myosin II, Hanako Yashiro, Andrew J. Loza, James B. Skeath, and Gregory D. Longmore

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Genome-wide RNAi screen identifies broadly-acting host factors that inhibit arbovirus infection, Ari Yasunaga, Sheri L. Hanna, Jianqing Li, Hyelim Cho, Patrick P. Rose, Anna Spiridigliozzi, Beth Gold, Michael S. Diamond, and Sara Cherry

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Complications associated with the periacetabular osteotomy, Ira Zaltz, Geneva Baca, Young-Jo Kim, Perry Schoenecker, Robert Trousdale, Rafael Sierra, Daniel Sucato, Ernie Sink, Paul Beaulé, Michael B. Millis, David Podeszwa, and John C. Clohisy

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HDAC and HAT inhibitors differently affect analgesia mediated by group II metabotropic glutamate receptors, Magda Zammataro, Maria Angela Sortino, Carmela Parenti, Robert W. Gereau, and Santina Chiechio

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Leishmania aethiopica field isolates bearing an endosymbiontic dsRNA virus induce pro-inflammatory cytokine response, Haroun Zangger, Asrat Hailu, Chantal Desponds, Lon-Fye Lye, Natalia S. Akopyants, Deborah E. Dobson, Catherine Ronet, Hashim Ghalib, Stephen M. Beverly, and Nicolas Fasel

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Comparison of perioperative outcomes of robot-assisted partial nephrectomy and open partial nephrectomy in patients with a solitary kidney, Homayoun Zargar, Sam Bhayani, Mohamad E. Allaf, Michael Stifelman, Craig Rogers, Jeffrey Larson, Mark W. Ball, Susan Marshall, Ramesh Kumar, Amr Fergany, Steven Campbell, and Jihad Kaouk

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Intrawound vancomycin powder eradicates surgical wound contamination: An in vivo rabbit study, Lukas P. Zebala, Tapanut Chuntarapas, Michael P. Kelly, Michael Talcott, Suellen Greco, and K. Daniel Riew

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Discrimination between thermodynamic models of cis-regulation using transcription factor occupancy data, Robert D. Zeigler and Barak A. Cohen

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Comparative DNA methylome analysis of endometrial carcinoma reveals complex and distinct deregulation of cancer promoters and enhancers, Bo Zhang, Xiao Yun Xing, Jing Li, Rebecca F. Lowdon, Yan Zhou, Nan Lin, Baoxue Zhang, Vasavi Sundaram, Katherine B. Chiappinelli, Ian S. Hagemann, David G. Mutch, Paul J. Goodfellow, and Ting Wang

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Loss of Trop2 causes ErbB3 activation through a neuregulin-1-dependent mechanism in the mesenchymal subtype of HNSCC, Kaihua Zhang, Lamont Jones, Sora Lim, Christopher A. Maher, Douglas Adkins, James Lewis, Randall J. Kimple, Elana J. Fertig, Christine H. Chung, Brian A. Van Tine, Matthew J. Ellis, Andreas Herrlich, and Loren S. Michel

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Application of noncollapsing methods to the gene-based association test: A comparison study using Genetic Analysis Workshop 18 data, Tian-Xiao Zhang, Yi-Ran Xie, and John P. Rice

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Radiosynthesis and in Vivo Evaluation of Two PET Radioligands for Imaging α-Synuclein, Xiang Zhang, Hongjun Jin, Prashanth K. Padakanti, Junfeng Li, Hao Yang, Jinda Fan, Robert H. Mach, Paul Kotzbauer, and Zhade Tu

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Elevated DDX21 regulates c-Jun activity and rRNA processing in human breast cancers, Yandong Zhang, Kathleen C. Baysac, Lian-Fai Yee, Anthony J. Saporita, and Jason D. Weber

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Resistin Stimulates Expression of Chemokine Genes in Chondrocytes via Combinatorial Regulation of C/EBPβ and NF-κB, Ziji Zhang, Zhiqi Zhang, Yan Kang, Changhe Hou, Xin Duan, Puyi Sheng, Linda J. Sandell, and Weiming Liao

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Natural antisense transcripts regulate the neuronal stress response and excitability, Xingguo Zheng, Vera Valakh, Aaron DiAntonio, and Yehuda Ben-Shahar

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Telomerase enzymatic component hTERT shortens long telomeres in human cells, Yun-Ling Zheng, Fan Zhang, Bing Sun, Juan Du, Chongkui Sun, Jie Yuan, Ying Wang, Lian Tao, Krishna Kota, Xuefeng Liu, Richard Schlegel, and Qin Yang

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Conversion of fibroblasts to neural cells by p53 depletion, Di Zhou, Zhen Zhang, Li-Ming He, Juan Du, Fan Zhang, Chong-Kui Sun, Yu Zhou, Xiao-Wei Wang, Ge Lin, Ke-Ming Song, Ling-Gang Wu, and Qin Yang

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Phenotypic and genotypic analysis of Clostridium difficile isolates: A single-center study, Yanjiao Zhou, Carey-Ann D. Burnham, Tiffany Hink, Lei Chen, Nurmohammad Shaikh, Aye Wollam, Erica Sodergren, George M. Weinstock, Phillip I. Tarr, and Erik R. Dubberke

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The conjunctival microbiome in health and trachomatous disease: A case control study, Yanjiao Zhou, Martin J. Holland, Pateh Makalo, Hassan Joof, Chrissy H. Roberts, David C.W. Mabey, Robin L. Bailey, Matthew J. Burton, George M. Weinstock, and Sarah E. Burr

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Exploration of bacterial community classes in major human habitats, Yanjiao Zhou, Kathie A. Mihindukulasuriya, Hongyu Gao, Patricio S. La Rosa, Kristine M. Wylie, John C. Martin, Karthik Kota, William D. Shannon, Makedonka Mitreva, Erica Sodergren, and George M. Weinstock

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Risk factors for recurrent Clostridium difficile infection (CDI) hospitalization among hospitalized patients with an initial CDI episode: A retrospective cohort study, Marya D. Zilberberg, Kimberly Reske, Margaret Olsen, Yan Yan, and Erik R. Dubberke

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Multi-drug resistance, inappropriate initial antibiotic therapy and mortality in Gram-negative severe sepsis and septic shock: A retrospective cohort study, Marya D. Zilberberg, Andrew F. Shorr, Scott T. Micek, Cristina Vazquez-Guillamet, and Marin H. Kollef

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Absence of Dap12 and the αvβ3 integrin causes severe osteopetrosis, Wei Zou and Steven L. Teitelbaum

Submissions from 2013

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Knowledge and practice related to compliance with mass drug administration during the Egyptian national filariasis elimination program, Khaled M. Abd Elaziz, Maged El-Setouhy, Mark H. Bradley, Reda M.R. Ramzy, and Gary J. Weil

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Exposure to chronic mild stress prevents kappa opioid-mediated reinstatement of cocaine and nicotine place preference, Ream Al-Hasani, Jordan G. McCall, and Michael R. Bruchas

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Promoting state health department evidence-based cancer and chronic disease prevention: A multi-phase dissemination study with a cluster randomized trial component, Peg Allen, Sonia Sequeira, Rebekah R. Jacob, Adriano Akira Hino, Katherine A. Stamatakis, Jenine K. Harris, Lindsay Elliott, Jon F. Kerner, Ellen Jones, Maureen Dobbins, Elizabeth A. Baker, and Ross C. Brownson

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The adverse effects of reduced cerebral perfusion on cognition and brain structure in older adults with cardiovascular disease, Michael L. Alosco, John Gunstad, Beth A. Jerskey, Xiaomeng Xu, Uraina S. Clark, Jason Hassenstab, Denise M. Cote, Edward G. Walsh, Donald R. Labbe, Richard Hoge, Ronald A. Cohen, and Lawrence H. Sweet

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A novel strategy to increase the proliferative potential of adult human β-cells while maintaining their differentiated phenotype, Haytham Aly, Nidhi Rohatgi, Connie A. Marshall, Tiffani C. Grossenheider, Hiroyuki Miyoshi, Thaddeus S. Stappenbeck, Scot J. Matkovich, and Michael L. McDaniel

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Observer ratings of neighborhoods: Comparison of two methods, Elena M. Andresen, Theodore K. Malmstrom, Mario Schootman, Fredric D. Wolinsky, J. Philip Miller, and Douglas K. Miller

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Hospital flood preparedness and flood-related psychological consequences in 15 provinces in central Thailand after implementation of a national guideline, Anucha Apisarnthanarak, Thana Khawcharoenporn, Keith F. Woeltje, and David K. Warren

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Association between the perceived environment and physical activity among adults in Latin America: A systematic review, Carlos M. Arango, Diana C. Paez, Rodrigo S. Reis, Ross C. Brownson, and Diana C. Parra

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Comparison of regional cerebral blood flow responses to hypoglycemia using pulsed arterial spin labeling and positron emission tomography, Ana Maria Arbelaez, Yi Su, Jewell B. Thomas, Amy C. Hauch, Tamara Hershey, and Beau M. Ances

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Statistical trends in the Journal of the American Medical Association and implications for training across the continuum of medical education, Lauren D. Arnold, Melissa Braganza, Rondek Salih, and Graham A. Colditz