The Open Access Publications collection contains peer-reviewed articles authored by Washington University School of Medicine faculty that have been published in open access journals or authorized by the publishers for open access availability. Open access works are generally defined as being publicly available online and free of most licensing and copyright restrictions. The Bernard Becker Medical Library maintains this collection in support of Washington University’s commitment to the principles of open access publishing and making the scholarly work and research results of our faculty as widely and easily available as possible.

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Submissions from 2017

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Rapid generation of hypomorphic mutations, Laura L. Arthur, Joyce J. Chung, Preetam Jankirama, Kathryn M. Keefer, Igor Kolotilin, Slavica Pavlovic-Djuranovic, Douglas L. Chalker, Vojislava Grbic, Rachel Green, Rima Menassa, Heather L. True, James B. Skeath, and Sergej Djuranovic

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Cognitive impairment and decline in cognitively normal older adults with high amyloid-β: A meta-analysis, Jenalle E. Baker, Yen Ying Lim, Robert H. Pietrzak, Jason Hassenstab, Peter J. Snyder, Colin L. Masters, and Paul Maruff

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Expression of Ifnlr1 on intestinal epithelial cells is critical to the antiviral effects of IFN-lambda against norovirus and reovirus, Megan T. Baldridge, Sanghyun Lee, Judy J. Brown, Nicole McAllister, Kelly Urbanek, Terence S. Dermody, Timothy J. Nice, and Herbert W. Virgin

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Knockout of lysosomal enzyme-targeting gene causes abnormalities in mouse pup isolation calls, Terra D. Barnes and Timothy E. Holy

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Intestinal epithelial-specific mTORC1 activation enhances intestinal adaptation after small bowel resection, Lauren Barron, Raphael C. Sun, Bola Aladegbami, Christopher R. Erwin, Brad W. Warner, and Jun Guo

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Impaired cardiac and skeletal muscle bioenergetics in children, adolescents, and young adults with Barth syndrome, Adil Bashir, Kathryn L. Bohnert, Dominic N. Reeds, Linda R. Peterson, Adam J. Bittel, Lisa de las Fuentes, Christina A. Pacak, Barry J. Byrne, and W. Todd Cade

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Partial nephrectomy for presumed renal cell carcinoma: Incidence, predictors, and perioperative outcomes of benign lesions, Tyler M. Bauman, Aaron M. Potretzke, Alec J. Wright, Brent A. Knight, Joel M. Vetter, and R. Sherburne Figenshau

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Are all competencies equal in the eyes of residents? A multicenter study of emergency medicine residents’ interest in feedback, Suzanne Bentley, Kevin Hu, Anne Messman, Tiffany Moadel, Sorabh Khandelwal, Heather Streich, and Joan Noelker

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Viral RNA at two stages of reovirus infection is required for the induction of necroptosis, Angela K. Berger, Bradley E. Hiller, Deepti Thete, Anthony J. Snyder, Encarnacion Perez Jr, Jason W. Upton, and Pranav Danthi

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Blood product transfusion in emergency department patients: A case-control study of practice patterns and impact on outcome, Alexander Beyer, Ryan Rees, Christopher Palmer, Brian T. Wessman, and Brian M. Fuller

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Improving community ambulation after hip fracture: Protocol for a randomised, controlled trial, E Binder and et al

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A novel method for the quantification of fatty infiltration in skeletal muscle, Nicole K. Blitz and Gretchen A. Meyer

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Seroprevalence of Zika virus in wild African green monkeys and baboons, Connor R. Buechler, Adam L. Bailey, Andrea M. Weiler, Gabrielle L. Barry, Meghan E. Breitbach, Laurel M. Stewart, Anna J. Jasinska, Nelson B. Freimer, Cristian Apetrei, Jane E. Phillips-Conroy, Clifford J. Jolly, Jeffrey Rogers, Thomas C. Friedrich, and David H. O'Connor

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The Brief Case: Central nervous system sparganosis in a 53-year-old Thai man, Abigail L. Carlson, Nattapol Pruetpongpun, Aubonphan Buppajarntham, Pansachee Damronglerd, Neil W. Anderson, and Anucha Apisarnthanarak

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Exacerbated leishmaniasis caused by a viral endosymbiont can be prevented by immunization with Its viral capsid, Patrick Castiglioni, Mary-Anne Hartley, Matteo Rossi, Florence Prevel, Chantal Desponds, Daniel T. Utzxchneider, Remzi-Onur Eren, Haroun Zangger, Livia Brunner, Nicolas Collin, Dietmar Zehn, F. Matthew Kuhlmann, Stephen M. Beverley, Nicolas Fasel, and Catherine Ronet

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Osteoarthritis: toward a comprehensive understanding of pathological mechanism, Di Chen, Jie Shen, Weiwei Zhao, Tingyu Wang, Lin Han, John L. Hamilton, and Hee-Jeong Im

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CD36 deficiency impairs the small intestinal barrier and induces subclinical inflammation in mice, Vincenza Cifarelli, Stoyan Ivanov, Yan Xie, Ni-Huiping Son, Brian T. Saunders, Terri A. Pietka, Trevor M. Shew, Jun Yoshino, Sinju Sundaresan, Nicholas O. Davidson, Ira J. Goldberg, Andrew E. Gelman, Bernd H. Zinselmeyer, Gwendalyn J. Randolph, and Nada A. Abumrad

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Patient-reported outcomes of periacetabular osteotomy from the prospective ANCHOR cohort study, John C. Clohisy, Jeffrey Ackerman, Geneva Baca, Jack Baty, Paul E. Beaule, Young-Jo Kim, Michael B. Millis, David A. Podeszwa, Perry L. Schoenecker, Rafael J. Sierra, Ernest L. Sink, Daniel J. Sucato, Robert T. Trousdale, and Ira Zaltz

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The norovirus NS3 protein is a dynamic lipid- and microtubule-associated protein involved in viral RNA replication, Ben T. Cotton, Jennifer L. Hyde, Soroush T. Sarvestani, Stanislav V. Sosnovtsev, Kim Y. Green, Peter A. White, and Jason M. Mackenzie

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Randomized trial of calcipotriol combined with 5-fluorouracil for skin cancer precursor immunotherapy, Trevor J. Cunningham, Mary Tabacchi, Jean-Pierre Eliane, Sara Moradi Tuchayi, Sindhu Manivasagam, Hengameh Mirzaalian, Ahu Turkoz, Raphael Kopan, Andras Schaffer, Arturo P. Saavedra, Michael Wallendorf, Lynn A. Cornelius, and Shadmehr Demehri

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Quantitative nucleotide level analysis of regulation of translation in response to depolarization of cultured neural cells, Jasbir S. Dalal, Chengran Yang, Darshan Sapkota, Allison M. Lake, David R. O'Brien, and Joseph D. Dougherty

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Expression and function of ATP-dependent potassium channels in zebrafish islet β-cells, Christopher H. Emfinger, Alecia Welscher, Zihan Yan, Yixi Wang, Hannah Conway, Jennifer B. Moss, Larry G. Moss, Maria S. Remedi, and Colin G. Nichols

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Realizing the potential of cancer prevention - the role of implementation science, Karen M. Emmons and Graham A. Colditz

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Continuing medical education speakers with high evaluation scores use more image-based slides, Ian Ferguson, Andrew W. Phillips, and Michelle Lin

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Potential value of triple drug therapy with ivermectin, diethylcarbamazine, and albendazole (IDA) to accelerate elimination of lymphatic filariasis and onchocerciasis in Africa, Peter U. Fischer, Christopher L. King, Julie A. Jacobson, and Gary J. Weil

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Bone mineral density and risk of heart failure in older adults: The Cardiovascular Health Study, Raymond B. Fohtung, David L. Brown, William J.H. Koh, Traci M. Bartz, Laura D. Carbone, Roberto Civitelli, Phyllis K. Stein, Paulo H.M. Chaves, Bryan R. Kestenbaum, and Jorge R. Kizer

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Effects of increasing the affinity of CarD for RNA polymerase on Mycobacterium tuberculosis growth, rRNA transcription, and virulence, Ashley L. Garner, Jayan Rammohan, Jeremy P. Huynh, Lucas M. Onder, James Chen, Brian Bae, Drake Jensen, Leslie A. Weiss, Ana Ruiz Manzano, Seth A. Darst, Elizabeth A. Campbell, Bryce E. Nickels, Eric A. Galburt, and Christina L. Stallings

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A double-blind, randomized, comparative study of the use of a combination of uridine triphosphate trisodium, cytidine monophosphate disodium, and hydroxocobalamin, versus isolated treatment with hydroxocobalamin, in patients presenting with compressive neuralgias, Henrique Goldberg, Marco Antonio Mibielli, Carlos Pereira Nunes, Stephanie Wrobel Goldberg, Luiz Buchman, Spyros GE Mezitis, Helio Rzetelna, Lisa Oliveria, Mauro Geller, and Fernanda Wajnsztajn

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Lineage A betacoronavirus NS2 proteins and the homologous torovirus Berne pp1a carboxy-terminal domain are phosphodiesterases that antagonize activation of RNase L, Stephen A. Goldstein, Joshua M. Thornbrough, Rong Zhang, Babal K. Jha, Yize Li, Ruth Elliott, Katherine Quiroz-Figueroa, Annie I. Chen, Robert H. Silverman, and Susan R. Weiss

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Recent positive selection in genes of the mammalian epidermal differentiation complex locus, Zane A. Goodwin and Cristina de Guzman Strong

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Fructose in breast milk is positively associated with infant body composition at 6 months of age, Michael I. Goran, Ashley A. Martin, Tanya L. Alderete, Hideji Fujiwara, and David A. Fields

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Actin/myosin-V- and activity-dependent inter-synaptic vesicle exchange in central neurons, Michael W. Gramlich and Vitaly A. Klyachko

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A postnatal role for embryonic myosin revealed by MYH3 mutations that alter TGFβ signaling and cause autosomal dominant spondylocarpotarsal synostosis, Dorothy K. Grange and et al

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Targeting dendritic cells to accelerate T-cell activation overcomes a bottleneck in tuberculosis vaccine efficacy, Kristin L. Griffiths, Mushtaq Ahmed, Shibali Das, Radha Gopal, William Horne, Terry D. Connell, Kelly D. Moynihan, Jay K. Kolls, Darrell J. Irvine, Maxim N. Artyomov, Javier Rangel-Moreno, and Shabaana A. Khader

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In vivo two-photon imaging of astrocytes in GFAP-GFP transgenic mice, Dongjun Guo, Jia Zou, Nicholas Rensing, and Michael Wong

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A Rab5 endosomal pathway mediates Parkin-dependent mitochondrial clearance, Babette C. Hammerling, Rita H. Najor, Melissa Q. Cortez, Sarah E. Shires, Leonardo J. Leon, Eileen R. Gonzalez, Daniela Boassa, Sébastien Phan, Andrea Thor, Rebecca E. Jimenez, Hong Li, Richard N. Kitsis, Gerald W. Dorn II, Junichi Sadoshima, Mark H. Ellisman, and Åsa B. Gustafsson

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Best anthropometric discriminators of incident type 2 diabetes among white and black adults: A longitudinal ARIC study, Dale S. Hardy, Devita T. Stallings, Jane T. Garvin, Hongyan Xu, and Susan B. Racette

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The Targeted SMAC Mimetic SW IV-134 is a strong enhancer of standard chemotherapy in pancreatic cancer, Yassar M. Hashim, Suwanna Vangveravong, Narendra V. Sankpal, Pratibha S. Binder, Jingxia Liu, S. Peter Goedegebuure, Robert H. Mach, Dirk Spitzer, and William G. Hawkins

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Pretreatment cognitive and neural differences between sapropterin dihydrochloride responders and non-responders with phenylketonuria, Zoe Hawks, Joshua Shimony, Jerrel Rutlin, Dorothy K. Grange, Shawn E. Christ, and Desiree A. White

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Computational assessment of potassium and magnesium ion binding to a buried pocket in GTPase-associating center RNA, Hamed S. Hayatshahi, Daniel R. Roe, Rodrigo Galindo-Murillo, Kathleen B. Hall, and Thomas E. Chetham III

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The role of mucosal immunity in the pathogenesis of necrotizing enterocolitis, Zerina Hodzic, Alexa M. Bolock, and Misty Good

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Multiplex shRNA screening of germ cell development by in vivo transfection of mouse testis, Nicholas R.Y. Ho, Abul R. Usmani, Yan Yin, Liang Ma, and Donald F. Conrad

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Splanchnic vein thrombosis in myeloproliferative neoplasms: Pathophysiology and molecular mechanisms of disease, Joan How, Amy Zhou, and Stephen T. Oh

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Independent test of a model to predict severe acute esophagitis, Ellen X. Huang, Clifford G. Robinson, Alerson Molotievschi, Jeffrey D. Bradley, Joseph O. Deasy, and Jung Hun Oh

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cis-regulatory circuits regulating NEK6 kinase overexpression in transformed B cells Are super-enhancer independent, Yue Huang, Olivia I. Koues, Jiang-yang Zhao, Regina Liu, Sarah C. Pyfrom, Jacqueline E. Payton, and Eugene M. Oltz

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Cell type-specific epigenomic analysis reveals a uniquely closed chormatin architecture in mouse rod photoreceptors, Andrew E. O. Hughes, Jennifer M. Enright, Connie A. Myers, Susan Q. Shen, and Joseph C. Corbo

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Osteolipoma of the knee, Tien-Phat V. Huynh, Cara C. Cipriano, Ian S. Hagemann, and Michael V. Friedman

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Esterase mutation is a mechanism of resistance to antimalarial compounds, Eva S. Istvan, Jeremy P. Mallari, Victoria C. Corey, Neekesh V. Dharia, Garland R. Marshall, Elizabeth A. Winzeler, and Daniel E. Goldberg

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Potential molecular consequences of transgene integration: The R6/2 mouse example, Jessie C. Jacobsen, Serkan Erdin, Colby Chiang, Carrie Hanscom, Renee R. Handley, Douglas D. Barker, Alex Stortchevoi, Ian Blumenthal, Suzanne J. Reid, Russell G. Snell, Marcy E. MacDonald, A. Jennifer Morton, Carl Ernst, James F. Gusella, and Michael E. Talkowski

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Potential molecular consequences of transgene integration: The R6/2 mouse example, Jessie C. Jacobsen, Serken Erdin, Colby Chiang, Carrie Hanscom, Renee R. Handley, Douglas D. Barker, Alex Stortchevoi, Ian Blumenthal, Suzanne J. Reid, Russell G. Snell, Marcy E. MacDonald, A. Jennifer Morton, Carl Ernst, James F. Gusella, and Michael E. Talkowski

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Statoviruses, a novel taxon of RNA viruses present in the gastrointestinal tracts of diverse mammals, Andrew B. Janowski, Siddharth R. Krishnamurthy, Efrem S. Lim, Guoyan Zhao, Jason M. Brenchley, Dan H. Barouch, Chrissie Thakwalakwa, Mark J. Manary, Lori R. Holtz, and David Wang

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Brain microvasculature defects and Glut1 deficiency syndrome averted by early repletion of the glucose transporter-1 protein, Lynne Jones and et al

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Mechanisms associated with activation of intracellular metabotropic glutamate receptor, mGluR5, Yuh-Jiin I. Jong and Karen L. O'Malley

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Evolutionary fine-tuning of conformational ensembles in FimH during host-pathogen interactions, Vasilios Kalas, Jerome S. Pinkner, Thomas J. Hannan, Michael E. Hibbing, Karen W. Dodson, Alex S. Holehouse, Hao Zhang, Niraj H. Tolia, Michael L. Gross, Rohit V. Pappu, James Janetka, and Scott J. Hultgren

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Mobilization of hematopoietic stem cells with the novel CXCR4 antagonist POL6326 (balixafortide) in healthy volunteers—Results of a dose escalation trial, Darja Karpova, Susanne Bräuninger, Eliza Wiercinska, Ariane Krämer, Belinda Stock, Jochen Graff, Hans Martin, Achim Wach, Christopher Escot, Garry Douglas, Barbara Romagnoli, Eric Chevalier, Klaus Dembowski, Leon Hooftman, and Halvard Bonig

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Biophysical evidence for intrinsic disorder in the C-terminal tails of the epidermal growth factor receptor (EGFR) and HER3 receptor tyrosine kinases, Theodore R. Keppel, Kwabena Sarpong, Elisa M. Murray, John Monsey, Jian Zhu, and Ron Bose

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Interrater reliability of surveillance for ventilator-associated events and pneumonia, Meeta Prasad Kerlin, William E. Trick, Deverick J. Anderson, Hilary M. Babcock, Ebbing Lautenbach, Renaud Gueret, and Michael Klompas

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Arginine deprivation inhibits the Warburg effect and upregulates glutamine anaplerosis and serine biosynthesis in ASS1-deficient cancers, Jeff Charles Kremer, Bethany Cheree Prudner, Sara Elaine Stubbs Lange, Gregory Richard Bean, Matthew Bailey Schultze, Caitlyn Brook Brashears, Megan DeAnna Radyk, Nathan Redlich, Shin-Cheng Tzeng, Aixiao Li, Zack Morgan, Jon McConathy, Loren Scott Michel, Jason Matthew Held, Brian Andrew Van Tine, and et al

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Evaluation of correlation between pretest probability for Clostridium difficile infection and Clostridium difficile enzyme immunoassay results, Jennie H. Kwon, Kimberly A. Reske, Tiffany Hink, Carey-Ann D. Burnham, and Erik R. Dubberke

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Temporal trends in satellite-derived erythemal UVB and implications for ambient sun exposure assessment, Marvin Langston, Leslie Dennis, Charles Lynch, Denise Roe, and Heidi Brown

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Anti-angiogenic nanotherapy inhibits airway remodeling and hyper-responsiveness of dust mite triggered asthma in the Brown Norway rat, Gregory M. Lanza, John Jenkins, Anne H. Schmieder, Aigul Moldobaeva, Grace Cui, Huiying Zhang, Xiaoxia Yang, Qiong Zhong, Jochen Keupp, Ismail Sergin, Krishna S. Paranandi, Lindsey Eldridge, John S. Allen, Todd Williams, Michael J. Scott, Babak Razani, and Elizabeth M. Wagner

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Inflammatory monocytes require type I interferon receptor signaling to activate NK cells via IL-18 during a mucosal viral infection, Amanda J. Lee, Branson Chen, Marianne V. Chew, Nicole G. Barra, Mira M. Shenouda, Tina Nham, Nico van Rooijen, Manel Jordana, Karen L. Mossman, Robert D. Schreiber, Matthias Mack, and Ali A. Ashkar

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Whole-genome DNA methylation profiling identifies epigenetic signatures of uterine carcinosarcoma, Jing Li, Xiaoyun Xing, Daofeng Li, Bo Zhang, David G. Mutch, Ian S. Hagemann, and Ting Wang

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Unintended targeting of Dmp1-Cre reveals a critical role for Bmpr1a signaling in the gastrointestinal mesenchyme of adult mice, Joohyun Lim, Joseph Burclaff, Guangxu He, Jason C. Mills, and Fanxin Long

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Serum phosphorus levels and risk of incident dementia, Tingting Li, Yan Xie, Benjamin Bowe, Hong Xian, and Ziyad Al-Aly

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Astrocytic LRP1 mediates brain Aβ clearance and impacts amyloid deposition, Chia-Chen Liu, Jin Hu, Na Zhao, Jian Wang, Wang Na, John R. Cirrito, Takahisa Kanekiyo, David M. Holtzman, and Guojun Bu

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A method to reconstruct and apply 3D primary fluence fortreatment delivery verification, Shi Liu, Thomas R. Mazur, Harold Li, Austen Curcuru, Olga L. Green, Baozhou Sun, Sasa Mutic, and Deshan Yang

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A single transcription factor is sufficient to induce and maintain secretory cell architecture, Hei-Yong G. Lo, Ramon U. Jin, Greg Sibbel, Dengqun Liu, Anju Karki, Matthew S. Joens, Blair B. Madison, Bo Zhang, Valerie Blanc, James A.J. Fitzpatrick, Nicholas O. Davidson, Stephen F. Konieczny, and Jason C. Mills

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MAVS Is essential for primary CD4 + T cell immunity but not for recall T cell responses following an attenuated West Nile virus infection, Huanle Luo, Evandro Winkelmann, Guorui Xie, Rong Fang, Bi-Hung Peng, Li Li, Helen M. Lazear, Slobodan Paessler, Michael S. Diamond, Michael Gale Jr, Alan D. Barrett, and Tian Wang

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Perceived barriers to achieving a healthy weight: A qualitative study using focus groups at public and private schools in Guatemala City, Luisa Madrigal, Inez Adams, Violeta Chacon, and Joaqin Barnoya

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A case report of the clear cell variant of gallbladder carcinoma, Ravi Maharaj, Christo Cave, Kevin Sarran, Nigel Bascombe, Dilip Dan, Wesley Greaver, and Wayne A. Warner

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Pelvic exenteration case series: A single surgeon’s experience at one institution in Trinidad and Tobago, Ravi Maharaj, Vandana Devika Sookdeo, Maurice Fortune, Meenakshi Akhilesh, Chalapathi Rao Adidam Venkata, Wayne Mohammed, Dave Harnanan, and Wayne A. Warner

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Hydraulic forces contribute to left ventricular diastolic filling, Elira Maksuti, Marcus Carlsson, Hakan Arheden, Sandor J. Kovacs, Michael Broome, and Martin Ugander

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The Surgical Infection Society revised guidelines on the management of intra-abdominal infection, John E. Mazuski, Jeffrey M. Tessier, Addison K. May, Robert G. Sawyer, Evan P. Nadler, Matthew R. Rosengart, Phillip K. Chang, Patrick J. O'Neill, Kevin P. Mollen, Jared M. Huston, Jose J. Diaz Jr, and Jose M. Prince

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Genomes of Fasciola hepatica from the Americas reveal colonization with Neorickettsia endobacteria related to the agents of Potomac horse and human Sennetsu fevers, Samantha N. McNulty, Bruce A. Rosa, Young-Jun Choi, Rahul Tyagi, Kymberlie Hallsworth-Pepin, Peter U. Fischer, Makedonka Mitreva, and et al.

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Recent advances in understanding, diagnosing, and treating ovarian cancer [version 1; referees: 3 approved], Kathryn Mills and Katherine Fuh

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Prostaglandin E2 promotes intestinal repair through an adaptive cellular response of the epithelium, Hiroyuki Miyoshi, Kelli L. VanDussen, Nicole P. Malvin, Stacy H. Ryu, Yi Wang, Naomi M. Sonnek, Chin-Wen Lai, and Thaddeus S. Stappenbeck

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Animal models of Zika virus infection, pathogenesis, and immunity, Thomas E. Morrison and Michael S. Diamond

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Human embryos cultured in vitro to 14 days, Samantha A. Morris

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Comparison of research framing preferences and information use of state legislators and advocates involved in cancer control, United States, 2012–2013, Alexandra B. Morshed, Elizabeth A. Dodson, Rachel G. Tabak, and Ross C. Brownson

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Novel treatment of chronic graft-versus-host disease in mice using the ER stress reducer 4-phenylbutyric acid, Shin Mukai, Yoko Ogawa, Fumihiko Urano, Chie Kudo-Saito, Yutaka Kawakami, and Kazuo Tsubota

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Inhibition of MAPK-Erk pathway in vivo attenuates aortic valve disease processes in Emilin1-deficient mouse model, Charu Munjal, Anil G. Jegga, Amy M. Opoka, Ivan Stoilov, Russell A. Norris, Craig J. Thomas, J. Michael Smith, Robert P. Mecham, Giorgio M. Bressan, and Robert B. Hinton

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A rare case of renal thrombotic microangiopathy associated with Castleman’s disease, Ahubha Mutneja, L. Nicholas Cossey, Helen Liapis, and Ying Maggie Chen

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Environmental enteric dysfunction and the fecal microbiota in malawian children, M. Isabel Ordiz, Kevin Stephenson, Sophia Agapova, Kristine M. Wylie, Ken Maleta, John Martin, Indi Trehan, Washington University School of Medicine in St. Louis, and Mark J. Manary

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Brain amyloid in preclinical Alzheimer's disease is associated with increased driving risk, Brian R. Ott, Richard N. Jones, Richard B. Noto, Don C. Yoo, Peter J. Snyder, Justine N. Bernier, David B. Carr, and Catherine M. Roe

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APOE genotype differentially modulates effects of anti-Aβ, passive immunization in APP transgenic mice, Joanna E. Pankiewicz, Jairo Baquero-Buitrago, Sandrine Sanchez, Jennifer Lopez-Contreras, Jungsu Kim, Patrick M. Sullivan, David M. Holtman, and Martin J. Sadowski

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A murine herpesvirus closely related to ubiquitous human herpesviruses causes T-cell depletion, Swapneel J. Patel, Guoyan Zhao, Vinay R. Penna, Eugene Park, Elvin J. Lauron, Ian B. Harvey, Wandy L. Beatty, Beatrice Plougastel-Douglas, Jennifer Poursine-Laurent, Daved H. Fremont, and Wayne M. Yokoyama

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Sigma-2 receptor agonist derivatives of 1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) induce cell death via mitochondrial superoxide production and caspase activation in pancreatic cancer, Maria Laura Pati, John R. Hornick, Mauro Niso, Francesco Berardi, Dirk Spitzer, Carmen Abate, and William Hawkins

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Consensus guideline for the diagnosis and treatment of aromatic l-amino acid decarboxylase (AADC) deficiency, Toni S. Pearson and et al

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Murine models of gastric corpus preneoplasia, Christine P. Petersen, Jason C. Mills, and James R. Goldenring

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Clinical outcomes of remote ischemic preconditioning prior to cardiac surgery: A meta‐Analysis of randomized controlled trials, Brian Pierce, Indra Bole, Vaiibhav Patel, and David L. Brown

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Enrichment and molecular analysis of breast cancer disseminated tumor cells from bone marrow using microfiltration, Sreeraj G. Pillai, Peixuan Zhu, Chidananda M. Siddappa, Daniel L. Adams, Shuhong Li, Olga V. Makarova, Pete Amstutz, Ryan Nunley, Cha-Mei Tang, Mark A. Watson, and Rebecca L. Aft

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Neural circuitry at age 6 months associated with later repetitive behavior and sensory responsiveness in autism, John R. Pruett Jr., Kelly N. Botteron, and et al

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Hotspots of aberrant enhancer activity punctuate the colorectal cancer epigenome, Shondra M. Pruett-Miller and et al

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Complete genome sequence of BK polyomavirus subtype Ib-1 detected in a kidney transplant patient with BK viremia using shotgun sequencing, Ravi Ranjan, Asha Rani, Daniel C. Brennan, Patricia W. Finn, and David L. Perkins

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Complete genome sequence of BK polyomavirus subtype Ib-1 detected in a kidney transplant patient with BK viremia using shotgun sequencing, Ravi Ranjan, Asha Rani, Daniel C. Brennan, Patricia W. Finn, and David L. Perkins

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Predicting blunt cerebrovascular injury in pediatric trauma: Validation of the "Utah Score", Vijay M. Ravindra, Robert J. Bollo, Walavan Sivakumar, Hassan Akbari, Robert P. Naftel, David D. Limbrick Jr, Andrew Jea, Stephen Gannon, Chevis Shannon, Yekaterina Birkas, George L. Yang, Colin T. Prather, John R. Kestle, and Jay Riva-Cambrin

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Diabetes induced by gain-of-function mutations in the Kir6.1 subunit of the KATP channel, Maria S. Remedi, Jonathan B. Friedman, and Colin G. Nichols

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Preclinical Alzheimer's disease and longitudinal driving decline, Catherine M. Roe, Ganesh M. Babulal, Denise M. Head, Sarah H. Stout, Elizabeth K. Vernon, Nupur Ghoshal, Peggy P. Barco, Ann Johnson, Rebecca Fierberg, M. Scot Fague, Chengjie Xiong, Elizabeth A. Grant, David M. Holtzman, Tammie L.S. Benzinger, Anne M. Fagan, David B. Carr, John C. Morris, and et al

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Genome sequence of Christensenella minuta DSM 22607T, Bruce A. Rosa, Kymberlie Hallsworth-Pepin, John Martin, Aye Wollam, and Makedonka Mitreva