The Open Access Publications collection contains peer-reviewed articles authored by Washington University School of Medicine faculty that have been published in open access journals or authorized by the publishers for open access availability. Open access works are generally defined as being publicly available online and free of most licensing and copyright restrictions. The Bernard Becker Medical Library maintains this collection in support of Washington University’s commitment to the principles of open access publishing and making the scholarly work and research results of our faculty as widely and easily available as possible.

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Submissions from 2019

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Apobec1 complementation factor (A1CF) and RBM47 interact in tissue-specific regulation of C to U RNA editing in mouse intestine and liver, Valerie Blanc, Yan Xie, Susan Kennedy, Jesse D. Riordan, Deborah C. Rubin, Blair B. Madison, Jason C. Mills, Joseph H. Nadeau, and Nicholas O. Davidson

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Re-estimating annual deaths due to multidrug-resistant organism infections, Jason P. Burnham, Margaret A. Olsen, and Marin H. Kollef

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KIAA1549-BRAF expression establishes a permissive tumor microenvironment through NFκB-mediated CCL2 production, Ran Chen, Chanel Keoni, Christopher A. Waker, Robert M. Lober, and David H. Gutmann

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Leishmania lipophosphoglycan triggers caspase-11 and the non-canonical activation of the NLRP3 inflammasome, Renan V.H. de Carvalho, Warrison A. Andrade, Djalma S. Lima-Junior, Marisa Dilucca, Caroline V. de Oliveira, Kun Wang, Paula M. Nogueira, Jeronimo N. Rugani, Rodrigo P. Soares, Stephen M. Beverley, Feng Shao, and Dario S. Zamboni

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Involvement of surfactant protein D in Ebola virus infection enhancement via glycoprotein interaction, Anne-Laure Favier, Olivier Reynard, Evelyne Gout, Martin van Eijk, Henk P. Haagsman, Erika Crouch, Viktor Volchkov, Christophe Peyrefitte, and Nicole M. Thielens

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A multi-institutional experience of MR-guided liver stereotactic body radiation therapy, Lauren E. Henke, Olga L. Green, Parag J. Parikh, and et al

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Clostridium difficile infection increases acute and chronic morbidity and mortality, Margaret A. Olsen, Dustin Stwalley, Clarisse Demont, and Erik R. Dubberke

Submissions from 2018

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Health Education Advanced Leadership for Zimbabwe (Healz): Developing the infrastructure to support curriculum reform, Eva M. Aagaard, Susan C. Connors, Amelia Challender, Jonathan Gandari, Kusum Nathoo, Margaret Borok, Midion Chidzonga, Michele Barry, Thomas Campbell, and James Hakim

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Safety and efficacy of combined ruxolitinib and decitabine in accelerated and blast-phase myeloproliferative neoplasms, Camille N. Abboud

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Internal dose escalation is associated with increased local control for non-small cell lung cancer (NSCLC) brain metastases treated with stereotactic radiosurgery (SRS), Christopher Abraham, Adam Garsa, Shahed N. Badiyan, Robert Drzymala, Deshan Yang, Todd DeWees, Christina Tsien, Joshua L. Dowling, Keith M. Rich, Michael R. Chicoine, Albert H. Kim, Eric C. Leuthardt, and Cliff Robinson

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Prostate-specific membrane antigen cleavage of vitamin B9 stimulates oncogenic signaling through metabotropic glutamate receptors, Samuel Achilefu and et al

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GPR56/ADG RG1 regulates development and maintenance of peripheral myelin, Sarah D. Ackerman, Amit Mogha, Breanne L. Harty, Mitchell D'Rozario, Nicholas E. Sanchez, Paul Gamble, Matthew R. MacEwan, Wilson Zachary Ray, Kelly R. Monk, and et al

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Granulocyte-derived extracellular vesicles activate monocytes and are associated with mortality in intensive care unit patients, Avril Adelman, Kenneth B. Schechtman, Philip C. Spinella, and et al

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Exploring neighborhood environments and active commuting in Chennai, India, Deepti Adlakha, J. A. Hipp, James F. Sallis, and Ross C. Brownson

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Turning is an important marker of balance confidence and walking limitation in persons with multiple sclerosis, Gautam Adusumilli, Samantha Lancia, Victoria A. Levasseur, Vaishak Amblee, Megan Orchard, Joanne M. Wagner, and Robert T. Naismith

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Genetic influences on eight psychiatric disorders based on family data of 4 408 646 full and half-siblings, and genetic data of 333 748 cases and controls, Arpana Agrawal and et al

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Peeling the onion: The outer layers of Cryptococcus neoformans, Daniel P. Agustinho, Liza C. Miller, Lucy X. Li, and Tamara L. Doering

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Resistance to 6-methylpurine is conferred by defective adenine phosphoribosyltransferase in Tetrahymena, Takahiko Akematsu, Andrew Findlay, Yasuhiro Fukuda, Ronald E. Pearlman, Josef Loidl, Eduardo Orias, and Eileen P. Hamilton

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A pilot study of viscoelastic monitoring in pediatric trauma: Outcomes and lessons learned, Bola Aladegbami, Pamela M. Choi, Martin S. Keller, and Adam M. Vogel

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Selective targeting of histone modification fails to prevent graft versus host disease after hematopoietic cell transplantation, Bader Alahmari, Matthew Cooper, Edward Ziga, Julie Ritchey, John F. DiPersio, and Jaebok Choi

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In vivo detection of optically-evoked opioid peptide release, Ream Al-Hasani, Jenny-Marie T. Wong, Omar S. Mabrouk, Jordan G. McCall, Gavin P. Schmitz, Kirsten A. Porter-Stransky, Brandon J. Aragona, Robert T. Kennedy, and Michael R. Bruchas

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A broad-spectrum antibiotic, DCAP, reduces uropathogenic Escherichia coli infection and enhances vorinostat anticancer activity by modulating autophagy, Giulia Allavena, Doriana Debellis, Roberto Marotta, Chetanchandra S. Joshi, Indira U. Mysorekar, and Benedetto Grimaldi

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Management practices to build evidence-based decision-making capacity for chronic disease prevention in Georgia: A case study, Peg Allen, Jean C. O'Connor, Leslie A. Best, Meenakshi Lakshman, Rebekah R. Jacob, and Ross C. Brownson

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Blood manufacturing methods affect red blood cell product characteristics and immunomodulatory activity, Ruqayyah J. Almizraq, Philip J. Norris, Heather Inglis, Somaang Menocha, Mathijs R. Wirtz, Nicole Juffermans, Suchitra Pandey, Philip C. Spinella, Jason P. Acker, and Jennifer A. Muszynski

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Design Thinking in health care, Myra Altman, Terry T.K. Huang, and Jessica Y. Breland

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Distinct roles for REV-ERBα and REV-ERBβ in oxidative capacity and mitochondrial biogenesis in skeletal muscle, Ariadna Amador, Sean Campbell, Melissa Kazantzis, Gary Lan, Thomas P. Burris, and Laura A. Solt

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Novel patient-centered approach to facilitate same-day discharge in patients undergoing elective percutaneous coronary intervention, Amit P. Amin, Patricia Crimmins-Reda, Samantha Miller, Brandon Rahn, Mary Caruso, Andrew Pierce, Brandy Dennis, Marissa Pendegraft, Katrine Sorensen, Howard I. Kurz, John M. Lasala, Alan Zajarias, Richard G. Bach, Hemant Kulkarni, and Jasvindar Singh

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Reversing the “risk‐treatment paradox” of bleeding in patients undergoing percutaneous coronary intervention: Risk‐concordant use of bleeding avoidance strategies is associated with reduced bleeding and lower costs, Amit P. Amin, Samantha Miller, Brandon Rahn, Mary Caruso, Andrew Pierce, Katrine Sorensen, Howard Kurz, Alan Zajarias, Richard Bach, Jasvindar Singh, John M. Lasala, Hemant Kulkarni, and Patricia Crimmins-Reda

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Retroperitoneal access for robotic renal surgery, Barrett G. Anderson, Alec J. Wright, Aaron M. Potretzke, and R. Sherburne Figenshau

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Probing the changes in gene expression due to α-crystallin mutations in mouse models of hereditary human cataract, Usha P. Andley, Eric Tycksen, Brittney N. McGlasson-Naumann, and Paul D. Hamilton

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Local collaborations for physical activity promotion: A network analysis, Douglas Roque Andrade, Leandro Martin Totaro Garcia, and Diana C. Parra Perez

An exome-wide sequencing study of lipid response to high-fat meal and fenofibrate in Caucasians from the GOLDN cohort, Ping An, Mary F. Feitosa, and Michael A. Province

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Assessment and treatment of pediatric sleep problems: Knowledge, skills, attitudes and practices in a group of community child psychiatrists, Ali Anwar, Michael D. Yingling, Alicia Zhang, Ujjwal Ramtekkar, and Ginger E. Nicol

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3D printing is a transformative technology in congenital heart disease, Shafkat Anwar, Gautam K. Singh, Jacob Miller, Monica Sharma, Peter Manning, Joseph J. Billadello, Pirooz Eghtesady, and Pamela K. Woodard

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Ability of postoperative delirium to predict intermediate-term postoperative cognitive function in patients undergoing elective surgery at an academic medical centre: Protocol for a prospective cohort study, Amrita Aranake-Chrisinger, Jenny Zhao Cheng, Maxwell R. Muench, Rose Tang, Angela Mickle Washington University School of Medicine in St. Louis, Hannah Maybrier, Nan Lin, Troy Wildes, Eric Lenze, and Michael Simon Avidan

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How well does the Family Longevity Selection Score work: A validation test using the Utah Population Database, Liubov S. Arbeeva, Heidi A. Hanson, Konstantin G. Arbeev, Alexander M. Kulminski, Eric Stallard, Svetlana V. Ukraintseva, Deqing Wu, Robert W. Boudreau, Michael A. Province, Ken R. Smith, and Anatoliy I. Yashin

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Endovascular treatment of acute ischaemic stroke under conscious sedation: Predictors of poor outcomes, Umeshkumar Athiraman, Arbi Ben Abdallah, Akash Kansagra, and Rene Tempelhoff

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Single-cell RNA-seq uncovers a robust transcriptional response to morphine by glia, Denis Avey, Sumithra Sankararaman, Aldrin K.Y. Yim, Ruteja Barve, Jeffrey Milbrandt, and Robi D. Mitra

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RNA-Seq identifies genes whose proteins are transformative in the differentiation of cytotrophoblast to syncytiotrophoblast, in human primary villous and BeWo trophoblasts, Christopher Azar, Mark Valentine, Julie Trausch-Azar, Todd Druley, D. Michael Nelson, and Alan L. Schwartz

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Driving outcomes among older adults: A systematic review on racial and ethnic differences over 20 years, Ganesh M. Babulal, Monique M. Williams, Sarah H. Stout, and Catherine M. Roe

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Quintupling inhaled glucocorticoids to prevent childhood asthma exacerbations, Leonard B. Bacharier, Avarham Beigelman, and et al

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Place learning overrides innate behaviors in Drosophila, Vincent Baggett, Aditi Mishra, Abigail L. Kehrer, Abbey O. Robinson, Paul Shaw, and Troy Zars

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A conserved circadian function for the Neurofibromatosis 1 gene, Lei Bai, Yool Lee, Cynthia T. Hsu, Julie A. Williams, Daniel Cavanaugh, Xiangzhong Zheng, Carly Stein, Paula Haynes, Han Wang, David H. Gutmann, and Amita Sehgal

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Multicenter evaluation of the Etest gradient diffusion method for ceftolozane-tazobactam susceptibility testing of Enterobacteriaceae and Pseudomonas aeruginosa, Adam L. Bailey, Tom Armstrong, Hari-Prakash Dwivedi, Gerald A. Denys, Janet Hindler, Shelley Campeau, Maria Traczewski, Romney Humphries, and Carey-Ann D. Burnham

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Genomic and molecular landscape of DNA damage repair deficiency across The Cancer Genome Atlas, Matthew H. Bailey, Li Ding, and et al

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A novel FAS mutation with variable expressivity in a family with unicentric and idiopathic multicentric Castleman disease, Turner S. Baker, Kristyne J. Gambino, Lawrence Schriefer, Jung-Yeon Lim, Karyn Meltz Steinberg, David C. Fajgenbaum, Alejandro Martin Garcia-Sancho, and Minji Byun

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Lenalidomide results in a durable complete remission in acute myeloid leukemia accompanied by persistence of somatic mutations and a T-cell infiltrate in the bone marrow, Dhruv Bansal, Kiran Vij, Gue Su Chang, Christopher A. Miller, John F. DiPersio, Ravi Vij, Sharon E. Heath, Peter Westervelt, John S. Welch, and Todd A. Fehniger

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A high throughput, functional screen of human Body Mass Index GWAS loci using tissue-specific RNAi Drosophila melanogaster crosses, Thomas J. Baranski, Aldi T. Kraja, Jill L. Fink, Mary Feitosa, Petra A. Lenzini, Ingrid B. Borecki, Ching-Ti Liu, L. Adrienne Cupples, Kari E. North, and Michael A. Province

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Diagnostic accuracy of the Ottawa 3DY and Short Blessed Test to detect cognitive dysfunction in geriatric patients presenting to the emergency department, David Barbic, Brian Kim, Qadeem Salehmohamed, Kate Kemplin, Christopher R. Carpenter, and Skye Pamela Barbic

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Demographic, physical and mental health assessments in the adolescent brain and cognitive development study: Rationale and description, Deanna M. Barch and et al

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The Adolescent Brain Cognitive Development (ABCD) study: Imaging acquisition across 21 sites, Deanna M. Barch, Michael P. Harms, Nico U.F. Dosenbach, and et al

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Paracrine osteoprotegerin and β-catenin stabilization support synovial sarcomagenesis in periosteal cells, Jared J. Barrott, Benjamin E. Illum, Huifeng Jin, Matthew L. Hedberg, Yanliang Wang, Allie Grossmann, Malay Haldar, Mario R. Capecchi, and Kevin B. Jones

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Rituximab plus lenalidomide in advanced untreated follicular lymphoma, Nancy Lee Bartlett and et al

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Sustained efficacy and detailed clinical follow-up of first-line ibrutinib treatment in older patients with chronic lymphocytic leukemia: Extended phase 3 results from RESONATE-2, Nancy L. Bartlett and et al.

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Brentuximab vedotin with chemotherapy for stage III or IV Hodgkin's lymphoma, N. L. Bartlett and et al

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Genetics and pathogenesis of diffuse large B-cell lymphoma, N. L. Bartlett and et al

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Posaconazole-induced hypertension and hypokalemia due to inhibition of the 11b-hydroxylase enzyme, Kevin Barton, T. Keefe Davis, Bess Marshall, Alexis Edward, and Neil H. White

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The presynaptic ribbon maintains vesicle populations at the hair cell afferent fiber synapse, Lars Becker, Michael E. Schnee, Mamiko Niwa, Willy Sun, Stephan Maxeiner, Sara Talaei, Bechara Kachar, Mark A. Rutherford, and Anthony J. Ricci

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Diltiazem improves contractile properties of skeletal muscle in dysferlin‐deficient BLAJ mice, but does not reduce contraction‐induced muscle damage, Morium Begam, Alyssa F. Collier, Amber L. Mueller, Renuka Roche, Sujay S. Galen, and Joseph A. Roche

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Bacterial biogeography of adult airways in atopic asthma, Avraham Beigelman, Mario Castro, and et al

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Genetically enhancing the expression of chemokine domain of CX3CL1 fails to prevent tau pathology in mouse models of tauopathy, Shane M. Bemiller, Nicole M. Maphis, Shane V. Formica, Gina N. Wilson, Crystal M. Miller, Guixiang Xu, Olga N. Kokiko-Cochran, Ki-Wook Kim, Steffen Jung, Judy L. Cannon, Samuel D. Crish, Astrid E. Cardona, Bruce T. Lamb, and Kiran Bhaskar

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Normal sleep bouts are not essential for C. elegans survival and FoxO is important for compensatory changes in sleep, Heather L. Bennett, Yulia Khoruzhik, Dustin Hayden, Huiyan Huang, Jarred Sanders, Melissa B. Walsh, David Biron, and Anne C. Hart

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Chronic cough is associated with long breaks in esophageal peristaltic integrity on high-resolution manometry, Michael C. Bennett, Amit Patel, Nitin Sainani, Dan Wang, Gregory S. Sayuk, and C Prakash Gyawali

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White matter hyperintensities and the mediating role of cerebral amyloid angiopathy in dominantly-inherited Alzheimer's disease, Tammie L. S. Benzinger, Daniel S. Marcus, Anne M. Fagan, Nigel J. Cairns, David M. Holtzman, Virginia Buckles, Eric McDade, Randall J. Bateman, John C. Morris, and et al.

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Point-of-sale marketing and context of marijuana retailers: Assessing reliability and generalizability of the marijuana retail surveillance tool, Carla J. Berg, Lisa Henriksen, Patricia Cavazos-Rehg, Gillian L. Schauer, and Bridget Freisthler

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High-fructose corn-syrup-sweetened beverage intake increases 5-hour breast milk fructose concentrations in lactating women, Paige K. Berger, David A. Fields, Ellen W. Demerath, Hideji Fujiwara, and Michael I. Goran

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Past trauma and future choices: Differences in discounting in low-income, urban African Americans, Carissa van den Berk-Clark, Joel Myerson, Leonard Green, and Richard A. Grucza

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Scholarly success of orthopaedic surgeons participating in the Clinician Scholar Career Development Program, David N. Bernstein, Michelle Lawson, Emmanuel N. Menga, Regis J. O'Keefe, Paul T. Rubery, and Addisu Mesfin

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Age trends in 30 day hospital readmissions: US national retrospective analysis, Jay G. Berry, James C. Gay, Karen Joynt Maddox, Eric A. Coleman, Emily M. Bucholz, Margaret R. O'Neill, Kevin Blaine, and Matthew Hall

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Identification of a transporter complex responsible for the cytosolic entry of nitrogen-containing bisphosphonates, Ewelina Betleja, Rashmi Nanjundappa, Tao Cheng, and Moe R. Mahjoub

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Topology of functional connectivity and hub dynamics in the beta band as temporal prior for natural vision in the human brain, Viviana Betti, Maurizio Corbetta, Francesco de Pasquale, Vincent Wens, and Stefania Della Penna

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Change in longitudinal trends in sleep quality and duration following breast cancer diagnosis: Results from the Women’s Health Initiative, Chloe M. Beverly, Michelle J. Naughton, Michael L. Pennell, Randi E. Foraker, Gregory Young, Lauren Hale, Elizabeth M. Cespedes Feliciano, Kathy Pan, Tracy E. Crane, Suzanne C. Danhauer, and Electra D. Paskett

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Cardiovascular disease risk factor responses to a type 2 diabetes care model including nutritional ketosis induced by sustained carbohydrate restriction at 1 year: An open label, non-randomized, controlled study, Nasir H. Bhanpuri, Sarah J. Hallberg, Paul T. Williams, Amy L. McKenzie, Kevin D. Ballard, Wayne W. Campbell, James P. McCarter, Stephen D. Phinney, and Jeff S. Volek

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Diagnostic errors in paediatric cardiac intensive care, Priya N. Bhat, John M. Costello, Ranjit Aiyagari, Paul J. Sharek, Claudia A. Algaze, Mjaye L. Mazwi, Stephen J. Roth, and Andrew Y. Shin

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CLIP-related methodologies and their application to retrovirology, Paul D. Bieniasz and Sebla B. Kutluay

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The relationship between spatial configuration and functional connectivity of brain regions, Janine Diane Bijsterbosch, Mark W. Wollrich, Matthew F. Glasser, Emma C. Robinson, Christian F. Beckmann, David C. Van Essen, Samuel J. Harrison, and Stephen M. Smith

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Software for web-based tic suppression training [version 2; referees: 3 approved], Jonathan K. Black and Kevin J. Black

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A systematic meta-analysis of oxygen-to-glucose and oxygen-to-carbohydrate ratios in the resting human brain, Tyler Blazey, Abraham Z. Snyder, Manu S. Goyal, Andrei G. Vlassenko, and Marcus E. Raichle

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Interleukin-17A promotes parietal cell atrophy by inducing apoptosis, Kevin A. Bockerstett, Luciana H. Osaki, Christine P. Petersen, Catherine W. Cai, Chun Fung Wong, Thanh-Long M. Nguyen, Eric L. Ford, Daniel F. Hoft, Jason C. Mills, James R. Goldenring, and Richard J. DiPaolo

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Efficient minimization of multipole electrostatic potentials in torsion space, Nicholas K. Bodmer and James J. Havranek

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Patient perception and preference of EUS-guided drainage over percutaneous drainage when endoscopic transpapillary biliary drainage fails: An international multicenter survey, Ahmed Bolkhir and et al

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False‑positive technetium‑99m methylene diphosphonate bone scan activity in the orbit in a patient with a history of breast carcinoma, Sarah E. Bonnet and Joel R. Palko

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Acquired whole-lung mismatched perfusion defects on pulmonary ventilation/perfusion scintigraphy, Andrew W. Bowman, Brittany K. Albers, and Manoj K. Jain

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Myeloablative autologous stem-cell transplantation for severe scleroderma, R. Brasington and et al

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The small heat shock protein HSPB1 protects mice from sepsis, Elisa R. Breed, Carolyn A. Hilliard, Benyam Yoseph, Rohit Mittal, Zhe Liang, Ching-Wen Chen, Eileen M. Burd, Luke P. Brewster, Laura M. Hansen, Rudolph L. Gleason Jr., Tej K. Pandita, Mandy L. Ford, Clayton R. Hunt, and Craig M. Coopersmith

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Mutations in the PH Domain of DNM1 are associated with a nonepileptic phenotype characterized by developmental delay and neurobehavioral abnormalities, Emily Brereton, Emily Fassi, Gabriel C. Araujo, Jonathan Dodd, Aida Telegrafi, Sheel J. Pathak, and Marwan Shinawi

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MLL1 is essential for retinal neurogenesis and horizontal inner neuron integrity, Diana S. Brightman, Rachel L. Grant, Philip A. Ruzycki, Ray Suzuki, Anne K. Hennig, and Shiming Chen

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Notch2-dependent DC2s mediate splenic germinal center responses, Carlos G. Briseno, Ansuman T. Satpathy, Jesse T. Davidson IV, Stephen T. Ferris, Vivek Durai, Prachi Bagadia, Kevin W. O'Connor, Derek J. Theisen, Theresa L. Murphy, and Kenneth M. Murphy

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Importance of site of infection and antibiotic selection in the treatment of carbapenem-resistant Pseudomonas aeruginosa sepsis, Nicholas S. Britt, David J. Ritchie, Marin H. Kollef, Carey-Ann D. Burnham, Michael J. Durkin, Nicholas B. Hampton, and Scott T. Micek

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Effort thrombosis of the subclavian artery as a consequence of a unique anomaly, Evan R. Brownie and Robert W. Thompson

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Scaling up evidence-based public health training, Carol A. Brownson, Peg Allen, Samuel C. Yang, Kathryn Bass, and Ross Brownson

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Sustaining knowledge translation interventions for chronic disease management in older adults: Protocol for a systematic review and network meta-analysis, Ross C. Brownson and et al

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Immune myopathies with perimysial pathology: Clinical and laboratory features, Robert C. Bucelli and Alan Pestronk

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Empiric antibiotics for sepsis, Sara A. Buckman, Isaiah R. Turnbull, and John E. Mazuski

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A qualitative exploration of contextual factors that influence dissemination and implementation of evidence-based chronic disease prevention across four countries, Elizabeth L. Budd, Anna J. deRuyter, Zhaoxin Wang, Pauline Sung-Chan, Xiangji Ying, Karishma S. Furtado, Tahna Pettman, Rebecca Armstrong, Rodrigo S. Reis, Jianwei Shi, Tabitha Mui, Tahnee Suanders, Leonardo Becker, and Ross C. Brownson

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Adverse events following single dose treatment of lymphatic filariasis: Observations from a review of the literature, Philip J. Budge, Carly Herbert, Britt J. Andersen, and Gary J. Weil

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Subclinical infection of macaques and baboons with a baboon simarterivirus, Connor R. Buechler, Matthew Semler, David A. Baker, Christina Newman, Joseph P. Cornish, Deborah Chavez, Bernadette Guerra, Robert Lanford, Kathy Brasky, Jens H. Kuhn, Reed F. Johnson, David H. O'Connor, and Adam L. Bailey

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Impact of amoxicillin-clavulanate followed by autologous fecal microbiota transplantation on fecal microbiome structure and metabolic potential, Christopher Bulow, Amy Langdon, Tiffany Hink, Meghan Wallace, Kimberly A. Reske, Sanket Patel, Xiaoqing Sun, Sondra Seiler, Susan Jones, Jennie H. Kwon, Carey-Ann D. Burnham, Gautam Dantas, Erik R. Dubberke, and CDC Prevention Epicenter Program

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Unilateral, 3D arm movement kinematics are encoded in ipsilateral human cortex, David T. Bundy, Nicholas Szrama, Mrinal Pahwa, and Eric C. Leuthardt

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Plasticity of differentiated cells in wound repair and tumorigenesis, Part II: Skin and intestine, Joseph Burclaff and Jason C. Mills