The Open Access Publications collection contains peer-reviewed articles authored by Washington University School of Medicine faculty that have been published in open access journals or authorized by the publishers for open access availability. Open access works are generally defined as being publicly available online and free of most licensing and copyright restrictions. The Bernard Becker Medical Library maintains this collection in support of Washington University’s commitment to the principles of open access publishing and making the scholarly work and research results of our faculty as widely and easily available as possible.

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Submissions from 2018

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Internal dose escalation is associated with increased local control for non-small cell lung cancer (NSCLC) brain metastases treated with stereotactic radiosurgery (SRS), Christopher Abraham, Adam Garsa, Shahed N. Badiyan, Robert Drzymala, Deshan Yang, Todd DeWees, Christina Tsien, Joshua L. Dowling, Keith M. Rich, Michael R. Chicoine, Albert H. Kim, Eric C. Leuthardt, and Cliff Robinson

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Prostate-specific membrane antigen cleavage of vitamin B9 stimulates oncogenic signaling through metabotropic glutamate receptors, Samuel Achilefu and et al

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GPR56/ADG RG1 regulates development and maintenance of peripheral myelin, Sarah D. Ackerman, Amit Mogha, Breanne L. Harty, Mitchell D'Rozario, Nicholas E. Sanchez, Paul Gamble, Matthew R. MacEwan, Wilson Zachary Ray, Kelly R. Monk, and et al

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Granulocyte-derived extracellular vesicles activate monocytes and are associated with mortality in intensive care unit patients, Avril Adelman, Kenneth B. Schechtman, Philip C. Spinella, and et al

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Resistance to 6-methylpurine is conferred by defective adenine phosphoribosyltransferase in Tetrahymena, Takahiko Akematsu, Andrew Findlay, Yasuhiro Fukuda, Ronald E. Pearlman, Josef Loidl, Eduardo Orias, and Eileen P. Hamilton

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Novel patient-centered approach to facilitate same-day discharge in patients undergoing elective percutaneous coronary intervention, Amit P. Amin, Patricia Crimmins-Reda, Samantha Miller, Brandon Rahn, Mary Caruso, Andrew Pierce, Brandy Dennis, Marissa Pendegraft, Katrine Sorensen, Howard I. Kurz, John M. Lasala, Alan Zajarias, Richard G. Bach, Hemant Kulkarni, and Jasvindar Singh

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Retroperitoneal access for robotic renal surgery, Barrett G. Anderson, Alec J. Wright, Aaron M. Potretzke, and R. Sherburne Figenshau

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Probing the changes in gene expression due to α-crystallin mutations in mouse models of hereditary human cataract, Usha P. Andley, Eric Tycksen, Brittney N. McGlasson-Naumann, and Paul D. Hamilton

An exome-wide sequencing study of lipid response to high-fat meal and fenofibrate in Caucasians from the GOLDN cohort, Ping An, Mary F. Feitosa, and Michael A. Province

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Assessment and treatment of pediatric sleep problems: Knowledge, skills, attitudes and practices in a group of community child psychiatrists, Ali Anwar, Michael D. Yingling, Alicia Zhang, Ujjwal Ramtekkar, and Ginger E. Nicol

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3D printing is a transformative technology in congenital heart disease, Shafkat Anwar, Gautam K. Singh, Jacob Miller, Monica Sharma, Peter Manning, Joseph J. Billadello, Pirooz Eghtesady, and Pamela K. Woodard

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Ability of postoperative delirium to predict intermediate-term postoperative cognitive function in patients undergoing elective surgery at an academic medical centre: Protocol for a prospective cohort study, Amrita Aranake-Chrisinger, Jenny Zhao Cheng, Maxwell R. Muench, Rose Tang, Angela Mickle Washington University School of Medicine in St. Louis, Hannah Maybrier, Nan Lin, Troy Wildes, Eric Lenze, and Michael Simon Avidan

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RNA-Seq identifies genes whose proteins are transformative in the differentiation of cytotrophoblast to syncytiotrophoblast, in human primary villous and BeWo trophoblasts, Christopher Azar, Mark Valentine, Julie Trausch-Azar, Todd Druley, D. Michael Nelson, and Alan L. Schwartz

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Driving outcomes among older adults: A systematic review on racial and ethnic differences over 20 years, Ganesh M. Babulal, Monique M. Williams, Sarah H. Stout, and Catherine M. Roe

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Quintupling inhaled glucocorticoids to prevent childhood asthma exacerbations, Leonard B. Bacharier, Avarham Beigelman, and et al

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Place learning overrides innate behaviors in Drosophila, Vincent Baggett, Aditi Mishra, Abigail L. Kehrer, Abbey O. Robinson, Paul Shaw, and Troy Zars

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A conserved circadian function for the Neurofibromatosis 1 gene, Lei Bai, Yool Lee, Cynthia T. Hsu, Julie A. Williams, Daniel Cavanaugh, Xiangzhong Zheng, Carly Stein, Paula Haynes, Han Wang, David H. Gutmann, and Amita Sehgal

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Genomic and molecular landscape of DNA damage repair deficiency across The Cancer Genome Atlas, Matthew H. Bailey, Li Ding, and et al

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A high throughput, functional screen of human Body Mass Index GWAS loci using tissue-specific RNAi Drosophila melanogaster crosses, Thomas J. Baranski, Aldi T. Kraja, Jill L. Fink, Mary Feitosa, Petra A. Lenzini, Ingrid B. Borecki, Ching-Ti Liu, L. Adrienne Cupples, Kari E. North, and Michael A. Province

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Diagnostic accuracy of the Ottawa 3DY and Short Blessed Test to detect cognitive dysfunction in geriatric patients presenting to the emergency department, David Barbic, Brian Kim, Qadeem Salehmohamed, Kate Kemplin, Christopher R. Carpenter, and Skye Pamela Barbic

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Paracrine osteoprotegerin and β-catenin stabilization support synovial sarcomagenesis in periosteal cells, Jared J. Barrott, Benjamin E. Illum, Huifeng Jin, Matthew L. Hedberg, Yanliang Wang, Allie Grossmann, Malay Haldar, Mario R. Capecchi, and Kevin B. Jones

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Brentuximab vedotin with chemotherapy for stage III or IV Hodgkin's lymphoma, N. L. Bartlett and et al

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Genetics and pathogenesis of diffuse large B-cell lymphoma, N. L. Bartlett and et al

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The presynaptic ribbon maintains vesicle populations at the hair cell afferent fiber synapse, Lars Becker, Michael E. Schnee, Mamiko Niwa, Willy Sun, Stephan Maxeiner, Sara Talaei, Bechara Kachar, Mark A. Rutherford, and Anthony J. Ricci

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Normal sleep bouts are not essential for C. elegans survival and FoxO is important for compensatory changes in sleep, Heather L. Bennett, Yulia Khoruzhik, Dustin Hayden, Huiyan Huang, Jarred Sanders, Melissa B. Walsh, David Biron, and Anne C. Hart

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Past trauma and future choices: Differences in discounting in low-income, urban African Americans, Carissa van den Berk-Clark, Joel Myerson, Leonard Green, and Richard A. Grucza

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Age trends in 30 day hospital readmissions: US national retrospective analysis, Jay G. Berry, James C. Gay, Karen Joynt Maddox, Eric A. Coleman, Emily M. Bucholz, Margaret R. O'Neill, Kevin Blaine, and Matthew Hall

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Diagnostic errors in paediatric cardiac intensive care, Priya N. Bhat, John M. Costello, Ranjit Aiyagari, Paul J. Sharek, Claudia A. Algaze, Mjaye L. Mazwi, Stephen J. Roth, and Andrew Y. Shin

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The relationship between spatial configuration and functional connectivity of brain regions, Janine Diane Bijsterbosch, Mark W. Wollrich, Matthew F. Glasser, Emma C. Robinson, Christian F. Beckmann, David C. Van Essen, Samuel J. Harrison, and Stephen M. Smith

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Interleukin-17A promotes parietal cell atrophy by inducing apoptosis, Kevin A. Bockerstett, Luciana H. Osaki, Christine P. Petersen, Catherine W. Cai, Chun Fung Wong, Thanh-Long M. Nguyen, Eric L. Ford, Daniel F. Hoft, Jason C. Mills, James R. Goldenring, and Richard J. DiPaolo

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Patient perception and preference of EUS-guided drainage over percutaneous drainage when endoscopic transpapillary biliary drainage fails: An international multicenter survey, Ahmed Bolkhir and et al

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Myeloablative autologous stem-cell transplantation for severe scleroderma, R. Brasington and et al

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Mutations in the PH Domain of DNM1 are associated with a nonepileptic phenotype characterized by developmental delay and neurobehavioral abnormalities, Emily Brereton, Emily Fassi, Gabriel C. Araujo, Jonathan Dodd, Aida Telegrafi, Sheel J. Pathak, and Marwan Shinawi

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Importance of site of infection and antibiotic selection in the treatment of carbapenem-resistant Pseudomonas aeruginosa sepsis, Nicholas S. Britt, David J. Ritchie, Marin H. Kollef, Carey-Ann D. Burnham, Michael J. Durkin, Nicholas B. Hampton, and Scott T. Micek

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Effort thrombosis of the subclavian artery as a consequence of a unique anomaly, Evan R. Brownie and Robert W. Thompson

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Immune myopathies with perimysial pathology: Clinical and laboratory features, Robert C. Bucelli and Alan Pestronk

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Empiric antibiotics for sepsis, Sara A. Buckman, Isaiah R. Turnbull, and John E. Mazuski

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A qualitative exploration of contextual factors that influence dissemination and implementation of evidence-based chronic disease prevention across four countries, Elizabeth L. Budd, Anna J. deRuyter, Zhaoxin Wang, Pauline Sung-Chan, Xiangji Ying, Karishma S. Furtado, Tahna Pettman, Rebecca Armstrong, Rodrigo S. Reis, Jianwei Shi, Tabitha Mui, Tahnee Suanders, Leonardo Becker, and Ross C. Brownson

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Clinical evaluation of the Cepheid Xpert TV assay for detection of Trichomonas vaginalis with prospectively collected specimens from men and women, C-A. D. Burnham, H. Reno, and et al

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Readmissions with multidrug-resistant infection in patients with prior multidrug resistant infection, Jason P. Burnham, Jennie H. Kwon, Margaret A. Olsen, Hilary M. Babcock, and Marin H. Kollef

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Infectious diseases consultation reduces 30-day and 1-year all-cause mortality for multidrug-resistant organism infections, Jason P. Burnham, Margaret A. Olsen, Dustin Stwalley, Jennie H. Kwon, Hilary M. Babcock, and Marin H. Koller

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Effects of cochlear implantation on binaural hearing in adults with unilateral hearing loss, Emily Buss, Margaret T. Dillon, Meredith A. Rooth, English R. King, Ellen J. Deres, Craig A. Buchman, Harold C. Pillsbury, and Kevin D. Brown

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First-in-human phase 1 study of the BTK inhibitor GDC-0853 in relapsed or refractory B-cell NHL and CLL, John C. Byrd, Stephen Smith, Nina Wagner-Johnston, Jeff Sharman, Andy I. Chen, Ranjana Advani, Bradley Auguston, Paula Marlton, S. Renee Commerford, Kwame Okrah, Lichuan Liu, Elaine Murray, Elicia Penuel, Ashley F. Ward, and Ian W. Flinn

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Normalize the response of EPID in pursuit of linearaccelerator dosimetry standardization, Bin Cai, S. Murty Goddu, Sridhar Yaddanapudi, Douglas Caruthers, Jie Wen, Camille Noel, Sasa Mutic, and Baozhou Sun

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A rapid, computational approach for assessing interfraction esophageal motion for use in stereotactic body radiation therapy planning, Michael L. Cardenas, Thomas R. Mazur, Christina I. Tsien, and Olga L. Green

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Deletion of Tsc2 in nociceptors reduces target innervation, ion channel expression, and sensitivity to heat, Dan Carlin, Judith P. Golden, Amit Mogha, Vijay K. Samineni, Kelly R. Monk, Robert W. Gereau, and Valeria Cavalli

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Natural killer cell recruitment to the lung during Influenza A virus infection is dependent on CXCR3, CCR5, and virus exposure dose, Lindsey E. Carlin, Emily A. Hemann, Zeb R. Zacharias, Jonathan W. Heusel, and Kevin L. Legge

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Heartland virus and hemophagocytic lymphohistiocytosis in immunocompromised patient, Missouri, USA, Abigail L. Carlson, Daniel M. Pastula, Amy J. Lambert, J. Erin Staples, Atis Muehlenbachs, George Turabelidze, Charles S. Eby, Jesse Keller, Brian Hess, Richard S. Buller, Gregory A. Storch, Kathleen Byrnes, Louis Dehner, Nigar Kirmani, and F. Matthew Kuhlmann

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Burosumab therapy in children with x-linked hypophosphatemia, Thomas O. Carpenter, Michael P. Whyte, Erik A. Imel, Annemieke M. Boot, Wolfgang Hogler, Agnes Linglart, Raja Padidela, William van't Hoff, Meng Mao, Chao-Yin Chen, Alison Skrinar, Emil Kakkis, Javier San Martin, and Anthony A. Portale

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Baseline features of the Severe Asthma Research Program (SARP III) cohort: Differences with age, Mario Castro, Andrea M. Coverstone, Leonard B. Bacharier, and et al

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Effects of endogenous sex hormones on lung function and symptom control in adolescents with asthma, Mario Castro, Andrea M. Coverstone, Leonard B. Bacharier, and et al

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Quantitative profiling of BATF family proteins/JUNB/IRF hetero-trimers using Spec-seq, Yiming K. Chang, Zheng Zuo, and Gary D. Stormo

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Local sequence features that influence AP-1 cis-regulatory activity, Hemangi G. Chaudhari and Barak A. Cohen

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Iron overload accelerates the progression of diabetic retinopathy in association with increased retinal renin expression, Kapil Chaudhary, Wanwisa Promsote, Sudha Ananth, Rajalakshmi Veeranan-Karmegam, Amany Tawfik, Pachiappan Arjunan, Pamela Martin, Sylvia B. Smith, Muthusamy Thangaraju, Oleg Kisselev, Vadivel Ganapathy, and Jaya P. Gnana-Prakasam

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The peroxisome proliferator-activated receptor agonist pioglitazone and 5-lipoxygenase inhibitor zileuton have no effect on lung inflammation in healthy volunteers by positron emission tomography in a single-blind placebo-controlled cohort study, Delphine L. Chen, Howard J. Huang, Derek E. Byers, Adrian Shifren, Bryan Belikoff, Jacquelyn T. Engle, Elizabeth Arentson, Debra Kemp, Sharon Phillips, David E. Scherrer, Hideji Fugiwara, Katherine J. Spayd, Frank J. Brooks, Richard A. Pierce, Mario Castro, and Warren Isakow

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Mapping two neurosteroid-modulatory sites in the prototypic pentameric ligand-gated ion channel GLIC, Wayland W. L. Cheng, Zi-Wei Chen, John R. Bracamontes, Melissa M. Budelier, Kathiresan Krishnan, Daniel J. Shin, Cunde Wang, Xin Jiang, Douglas F. Covey, Gustav Akk, and Alex S. Evers

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Current trends in the management of Mirizzi Syndrome: A review of literature, Hang Chen, Ernest Amos Siwo, Megan Khu, and Yu Tian

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Neurodegenerative disease biomarkers Aβ1–40, Aβ1–42, tau, and p-tau181 in the vervet monkey cerebrospinal fluid: Relation to normal aging, genetic influences, and cerebral amyloid angiopathy, Jason A. Chen, Scott C. Fears, Anna J. Jasinska, Alden Huang, Noor B. Al-Sharif, Kevin E. Scheibel, Thomas D. Dyer, Anne M. Fagan, John Blangero, Roger Woods, Matthew J. Jorgensen, Jay R. Kaplan, Nelson B. Freimer, and Giovanni Coppola

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mTOR signaling in skeletal development and disease, Jianquan Chen and Fanxin Long

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Obstructive sleep apnea knowledge and attitudes among recent medical graduates training in Ecuador, Ivan Cherrez-Ojeda, Juan Carlos Calderon, Andrea Fernandez Garcia, Donna B. Jeffe, Ilka Santoro, Emanuel Vanegas, Annia Cherrez, Jose Cano, Freddy Betancourt, and Daniel Simancas-Racines

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Methylation-based enrichment facilitates low-cost, noninvasive genomic scale sequencing of populations from feces, Kenneth L. Chiou and Christina M. Bergey

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Nanogels for pharmaceutical and biomedical applications and their fabrication using 3D printing technologies, Hyunah Cho, Udayabhanu Jammalamadaka, and Karthik Tappa

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Dietary nitrate-induced increases in human muscle power: High versus low responders, Andrew R. Coggan, Seth R. Broadstreet, Deana Mikhalkova, Indra Bole, Joshua L. Leibowitz, Ana Kadkhodayan, Soo Park, Deepak P. Thomas, Dakkota Thies, and Linda R. Peterson

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Accurate PCR detection of influenza A/B and respiratory syncytial viruses by use of Cepheid Xpert Flu+RSV Xpress Assay in point-of-care settings: Comparison to Prodesse ProFlu+, Daniel M. Cohen, Jennifer Kline, Larissa S. May, Glenn Eric Harnett, Jane Gibson, Stephen Y. Liang, Zubaid Rafique, Carina A. Rodriguez, Kevin M. McGann Sr., Charlotte A. Gaydos, Donna Mayne, David Phillips, and Jason Cohen

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Nusinersen versus sham control in later-onset spinal muscular atrophy, A. M. Connolly and et al

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PTRE-seq reveals mechanism and interactions of RNA binding proteins and miRNAs, Kyle A. Cottrell, Hemangi G. Chaudhari, Barak A. Cohen, and Sergej Djuranovic

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Diagnosis of LVAD thrombus using a high-avidity fibrin-specific 99mTc probe, Grace Cui, Walter J. Akers, Michael J. Scott, Michael Nassif, John S. Allen, Anne H. Schmieder, Krishna S. Paranandi, Akinobu Itoh, Dmitry D. Beyder, Samuel Achilefu, and Gregory A. Ewald

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Cervical clear cell adenocarcinoma with an exceptionally low proliferation index: Report of a case, Mary G. Dandulakis, Aidas J. Mattis, Andrea R. Hagemann, and Ian S. Hagemann

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Delayed hypoxemia after traumatic brain injury exacerbates long-term behavioral deficits, McKenzie Davies, Addison Jacobs, David L. Brody, and Stuart H. Friess

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Incorporating spatial dose metrics in machine learning-based normal tissue complication probability (NTCP) models of severe acute dysphagia resulting from head and neck radiotherapy, Jamie Dean, Kee Wong, Hiram Gay, Liam Welsh, Ann-Britt Jones, Ulricke Schick, Jung Hun Oh, Aditya Apte, Kate Newbold, Shreerang Bhide, Kevin Harrington, Joseph Deasy, Christopher Nutting, and Sarah Gulliford

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Cyclooxygenase-2 deficiency causes delayed ossification of lumbar vertebral endplates, Qingfeng Ding, Yongxin Ren, Hui Che, Cheng Ma, Huiwu Li, Suojing Yu, Yejia Zhang, Howard An, Regis J. O'Keefe, Di Chen, Joel A. Block, Guoyong Yin, and Tianfang Li

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Quantitative assessment of prefrontal cortex in humans relative to nonhuman primates, Chad J. Donahue, Matthew F. Glasser, Todd M. Preuss, James K. Rilling, and David C. Van Essen

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Compact, multi-exposure speckle contrast optical spectroscopy (SCOS) device for measuring deep tissue blood flow, Tanja Dragojević, Joseph L. Hollmann, Davide Tamborini, Davide Portaluppi, Mauro Buttafava, Joseph P. Culver, Federica Villa, and Turgut Durduran

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Physical therapy and deep brain stimulation in Parkinson’s Disease: Protocol for a pilot randomized controlled trial, Ryan P. Duncan, Linda R. Van Dillen, Jane M. Garbutt, Gammon M. Earhart, and Joel S. Perlmutter

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Outpatient antibiotic prescription trends in the United States: A national cohort study, Michael J. Durkin, S. Reza Jafarzadeh, Kevin Hsueh, Ya Haddy Sallah, Kiraat D. Munshi, Rochelle R. Henderson, and Victoria J. Fraser

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Attention-deficit/hyperactivity disorder symptoms are associated with overeating with and without loss of control in youth with overweight/obesity, Amy Heard Egbert, Denise E. Wilfley, Kamryn T. Eddy, Kerri N. Boutelle, Nancy Zucker, Carol B. Peterson, Angela Celio Doyle, Daniel Le Grange, and Andrea B. Goldschmidt

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New sequencing technologies help revealing unexpected mutations in autosomal dominant hypercholesterolemia, Sandy Elbitar, Delia Susan-Resiga, Youmna Ghaleb, Petra El Khoury, Gina Peloso, Nathan Stitziel, Jean-Pierre Rabès, Valérie Carreau, Josée Hamelin, Ali Ben- Djoudi-Ouadda, Eric Bruckert, Catherine Boileau, Nabil G. Seidah, Mathilde Varret, and Marianne Abifadel

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Understanding mechanisms to promote successful aging in persons living with HIV, Gerome V. Escota, Jane A. O'Halloran, William G. Powderly, and Rachel M. Presti

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Two-year outcomes with a magnetically levitated cardiac pump in heart failure, Gregory A. Ewald, Akinbou Itoh, and et al

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Xenosurveillance reflects traditional sampling techniques for the identification of human pathogens: A comparative study in West Africa, Joseph R. Fauver, James Weger-Lucarelli, Lawrence S. Fakoli III, Kpehe Bolay, Fatorma K. Bolay, Joseph W. Diclaro II, Doug E. Brackney, Brian D. Foy, Mark D. Stenglein, and Gregory D. Ebel

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Mouse and human monoclonal antibodies protect against infection by multiple genotypes of Japanese encephalitis virus, Estefania Fernandez, Nurgun Kose, Melissa A. Edeling, Jagat Adhikari, Gopal Sapparapu, Susana M. Lazarte, Christopher A. Nelson, Jennifer Govero, Michael L. Gross, Daved H. Fremont, James E. Crowe Jr., and Michael S. Diamond

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Evaluation of gene-based family-based methods to detect novel genes associated with familial late onset Alzheimer disease, Maria V. Fernandez, John Budde, Jorge L. Del-Aguila, Laura Ibanez, Yuetiva Deming, Oscar Harari, Joanne Norton, John C. Morris, Alison M. Goate, NIA-LOAD family study group, NCRAD, and Carlos Cruchaga

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c-Myb and C/EBPβ regulate OPN and other senescence-associated secretory phenotype factors, Kevin C. Flanagan, Elise Alspach, Ermira Pazolli, Shankar Parajuli, Qihao Ren, Laura L. Arthur, Roberto Tapia, and Sheila A. Stewart

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Slow gait speed and cardiac rehabilitation participation in older adults after acute myocardial infarction, Kelsey Flint, Kevin Kennedy, Suzanne V. Arnold, John A. Dodson, Sharon Cresci, and Karen P. Alexander

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The effects of graded caloric restriction: XII. Comparison of mouse to human impact on cellular senescence in the colon, Luigi Fontana, Sharon E. Mitchell, Boshi Wang, Valeria Tosti, Thijmen van Vliet, Nicola Veronese, Beatrice Bertozzi, Dayna S. Early, Parcival Maissan, John R. Speakman, and Marco Demaria

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TRPV1 agonist, capsaicin, induces axon outgrowth after injury via Ca2+/PKA signaling, Erin Frey, Scott Karney-Grobe, Trevor Krolak, Jeff Milbrandt, and Aaron DiAntonio

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Unintended side effects of transformation are very rare in Cryptococcus neoformans, Ryan Z. Friedman, Stacey R. Gish, Holly Brown, Lindsey Brier, Nicole Howard, Tamara L. Doering, and Michael R. Brent

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Extensive metastatic sarcomatoid renal cell carcinoma evaluated by 18F-FDG PET/CT: A case report and review of literature, Dominique Fuser, Matthew L. Hedberg, Louis P. Dehner, Farrokh Dehdashti, and Barry A. Siegel

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Coupling of rigor mortis and intestinal necrosis during C. elegans organismal death, Evgeniy R. Galimov, Rosina E. Pryor, Sarah E. Poole, Alexandre Benedetto, Zachary Pincus, and David Gems

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Driver fusions and their implications in the development and treatment of human cancers, Qingsong Gao, Wen-wei Liang, Steven M. Foltz, Gnanavel Mutharasu, Reyka G. Jayasinghe, Song Cao, Wen-wei Liao, Sheila M. Reynolds, Matthew A. Wyczalkowski, Lijun Yao, Lihua Yu, Sam Q. Sun, The Fusion Analysis Working Group, The Cancer Genome Atlas Research Network, Ken Chen, Alexander J. Lazar, Ryan C. Fields, Michael C. Wendl, Brian A. Van Tine, Ravi Vij, Feng Chen, Matti Nykter, Ilya Shmulevich, and Li Ding

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Theory-based development of an implementation intervention to increase HPV vaccination in pediatric primary care practices, Jane M. Garbutt, Sherry Dodd, Emily Walling, Amanda A. Lee, Katharine Kulka, and Rebecca Lobb

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Impaired granulocyte-macrophage colony-stimulating factor bioactivity accelerates surgical recurrence in ileal Crohn’s disease, Grace Gathungu, Yuanhao Zhang, Xinyu Tian, Erin Bonkowski, Leahana Rowehl, Julia Krumsiek, Billy Nix, Claudia Chalk, Bruce Trapnell, Wei Zhu, Rodney Newberry, Lee Denson, and Ellen Li

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Comparing deep learning and concept extraction based methods for patient phenotyping from clinical narratives, Sebastian Gehrmann, Franck Dernoncourt, Yeran Li, Eric T. Carlson, Joy T. Wu, Jonathan Welt, John Foote Jr., Edward T. Moseley, David W. Grant, Patrick D. Tyler, and Leo A. Celi

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Consumption of NADPH for 2-HG synthesis increases pentose phosphate pathway flux and sensitizes cells to oxidative stress, Susan J. Gelman, Fuad Naser, Nathaniel G. Mahieu, Lisa D. McKenzie, Gavin P. Dunn, Milan G. Chheda, and Gary J. Patti

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Homozygous KSR1 deletion attenuates morbidity but does not prevent tumor development in a mouse model of RAS-driven pancreatic cancer, Elizabeth A. Germino, Joseph P. Miller, Lauri Diehl, Carter J. Swanson, Steffen Durinck, Zora Modrusan, Jeffrey H. Miner, and Andrey S. Shaw

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Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction, David S. Gierada, Mario Castro, and et al

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Bridging the chasm: Challenges, opportunities, and resources for integrating a dissemination and implementation science curriculum into medical education, Tamar Ginossar, Carolyn J. Heckman, Deborah Cragun, Lisa M. Quintiliani, Enola K. Proctor, David A. Chambers, Ted Skolarus, and Ross C. Brownson

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Myeloid ERK5 deficiency suppresses tumor growth by blocking protumor macrophage polarization via STAT3 inhibition, Emanuele Giurisato, Qiuping Xu, Silvia Lonardi, Brian Telfer, Ilaria Russo, Adam Pearson, Katherine G. Finegan, Wenbin Wang, Jinhua Wang, Nathanael S. Gray, William Vermi, Zhengui Xia, and Cathy Tournier

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The p53 tumor suppressor in the control of metabolism and ferroptosis, Keerthana Gnanapradeepan, Subhasree Basu, Thibaut Barnoud, Anna Budina-Kolomets, Che-Pei Kung, and Maureen E. Murphy

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Holobiont diversity in a reef-building coral over its entire depth range in the mesophotic zone, Fanny L. Gonzalez-Zapata, Pim Bongaerts, Catalina Ramirez-Portilla, Boahemaa Adu-Oppong, Gretchen Walljasper, Alejandro Reyes, and Juan A. Sanchez