The Open Access Publications collection contains peer-reviewed articles authored by Washington University School of Medicine faculty that have been published in open access journals or authorized by the publishers for open access availability. Open access works are generally defined as being publicly available online and free of most licensing and copyright restrictions. The Bernard Becker Medical Library maintains this collection in support of Washington University’s commitment to the principles of open access publishing and making the scholarly work and research results of our faculty as widely and easily available as possible.

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Submissions from 2015

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Personality and well-being in adolescents, Paulo A.S. Moreira, C. Robert Cloninger, Liliana Dinis, Laura Sa, Joao T. Oliveira, Adelaide Dias, and Joana Oliveira

Large-scale genomics unveil polygenic architecture of human cortical surface area, John Morris, Marc Raichle, Davie Holtzman, Nigel J. Cairns, Erin Householder, Lisa Taylor-Reinwald, and et al.

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Trial of early, goal-directed resuscitation for septic shock, Paul R. Mouncey, Tiffany M. Osborn, G. Sarah Power, David A. Harrison, M. Zia Sadique, Richard D. Grieve, Rahi Jahan, Sheila E. Harvey, Derek Bell, Julian F. Bion, Timothy J. Coats, Mervyn Singer, J. Duncan Young, and Kathryn M. Rowan

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Multi-platform profiling of over 2000 sarcomas: Identification of biomarkers and novel therapeutic targets, Sujana Movva, Wenhsiang Wen, Wangjuh Chen, Sherri Z. Millis, Zoran Gatalica, Sandeep Reddy, Margaret von Mehren, and Brian A. Van Tine

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Circadian clock disruption in neurodegenerative diseases: Cause and effect?, Erik S. Musiek

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Sleep, circadian rhythms, and the pathogenesis of Alzheimer Disease., Erik S. Musiek, David D. Xiong, and David M. Holtzman

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Sumoylation is developmentally regulated and required for cell pairing during conjugation in Tetrahymena thermophila, Amjad M. Nasir, Qianyi Yang, Douglas L. Chalker, and James D. Forney

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Spatial and temporal characteristics of error-related activity in the human brain, Maital Neta, Francis M. Miezin, Steven M. Nelson, Joseph W. Dubis, Nico U. F. Dosenbach, Bradley L. Schlaggar, and Steven E. Petersen

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Using whole-genome sequences of the LG/J and SM/J inbred mouse strains to prioritize quantitative trait genes and nucleotides, Igor Nikolskiy, Donald F. Conrad, Sung Chun, Justin C. Fay, James M. Cheverud, and Heather A. Lawson

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ERK2 alone drives inflammatory pain but cooperates with ERK1 in sensory neuron survival, Daniel E. O'Brien, Benedict J. Alter, Maiko Satomoto, Clinton D. Morgan, Steve Davidson, Sherri K. Vogt, Megan E. Norman, Graydon B. Gereau, Joseph A. Demaro III, Gary E. Landreth, Judith P. Golden, and Robert W. Gereau IV

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Deletion of macrophage vitamin D receptor promotes insulin resistance and monocyte cholesterol transport to accelerate atherosclerosis in mice, Jisu Oh, Amy E. Riek, Isra Darwech, Katsuhiko Funai, JianSu Shao, Kathleen Chin, Oscar L. Sierra, Geert Carmeliet, Richard E. Ostlund Jr., and Carlos Bernal-Mizrachi

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Stratification of surgical site infection by operative factors and comparison of infection rates after hernia repair, Margaret A. Olsen, Katelin B. Nickel, Anna E. Wallace, Daniel Mines, Victoria J. Fraser, and David K. Warren

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Regulation of renal hemodynamics and function by RGS2, Patrick Osei-Owusu, Elizabeth A. Owens, Li Jie, Janaina S. Reis, Steven J. Forrester, Tatsuo Kawai, Satoru Eguchi, Harpreet Singh, and Kendall J. Blumer

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Full thickness macular hole case after intravitreal aflibercept treatment, Yuji Oshima, Rajendra S. Apte, Shintaro Nakao, Shigeo Yoshida, and Tatsuro Ishibashi

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Fmrp targets or not: Long, highly brain-expressed genes tend to be implicated in autism and brain disorders, Rebecca L. Ouwenga and Joseph Dougherty

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Streptococcus pyogenes malate degradation pathway links pH regulation and virulence, Elyse Paluscio and Michael G. Caparon

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Detailed phenotypic and molecular analyses of genetically modified mice generated by CRISPR-Cas9-mediated editing, Bijal A. Parikh, Diana L. Beckman, Swapneel J. Patel, J. Michael White, and Wayne M. Yokoyama

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Delayed surgical intervention in central cord syndrome with cervical stenosis, Moon S. Park, Seong-Hwan Moon, Hwan-Mo Lee, Tae-Hwan Kim, Jae K. Oh, Bo-Kyung Suh, Seung J. Lee, and K. D. Riew

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The nutrition transition in Colombia over a decade: A novel household classification system of anthropometric measures, Diana C. Parra, Lora Iannotti, Luis F. Gomez, Helena Pachon, Debra Haire-Joshu, Olga L. Sarmiento, Anne Sebert Kuhlmann, and Ross C. Brownson

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Travel advice for the immunocompromised traveler: prophylaxis, vaccination, and other preventive measures, Rupa R. Patel, Stephen Y. Liang, Pooja Koolwal, and Frederick Matthew Kuhlmann

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Comparison of chromogenic media for recovery of carbapenemase-producing enterobacteriaceae (CPE) and evaluation of CPE prevalence at a tertiary care academic medical center, Morgan A. Pence, Tiffany Hink, and Carey-Ann D. Burnham

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Rice Xa21 primed genes and pathways that are critical for combating bacterial blight infection, Hai Peng, Zheng Chen, Zhiwei Fang, Junfei Zhou, Zhihui Xia, Lifen Gao, Lihong Chen, Lili Li, Tiantian Li, Wenxue Zhai, and Weixiong Zhang

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Perilesional edema in radiation necrosis reflects axonal degeneration, Carlos J. Perez-Torres, Liya Yuan, Robert E. Schmidt, Keith M. Rich, Joseph JH Ackerman, and Joel R. Garbow

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Functional characterization of bacteria isolated from ancient Arctic soil exposes diverse resistance mechanisms to modern antibiotics, Gabriel G. Perron, Lyle Whyte, Peter J. Turnbaugh, Jacqueline Goordial, William P. Hanage, Gautam Dantas, and Michael M. Desai

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Active displacement of RecA filaments by UvrD translocase activity, Vessela Petrova, Stefanie H. Chen, Eileen T. Molzberger, Eric Tomko, Sindhu Chitteni-Pattu, Haifeng Jia, Yerdos Ordabayev, Timothy M. Lohman, and Michael M. Cox

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Depth of anesthesia as a risk factor for perioperative morbidity, Argyro Petsiti, Vassilios Tassoudis, George Vretzakis, Dimitrios Zacharoulis, Konstantinos Tepetes, Georgia Ganeli, and Menelaos Karanikolas

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Peptide-siRNA nanotherapeutics in arthritis, Christine T N Pham, Hua Pan, and Samuel A. Wickline

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The number of discharge medications predicts thirty-day hospital readmission: A cohort study, David Picker, Kevin Heard, Thomas C. Bailey, Nathan R. Martin, Gina N. LaRossa, and Marin H. Kollef

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Adrenocortical zonation, renewal, and remodeling, Marjut Pihlajoki, Julia Dorner, Rebecca S. Cochran, Markku Heikinheimo, and David B. Wilson

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Therapeutic hypothermia after out-of-hospital cardiac arrest in children, Jose A. Pineda and et al

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A cost-effectiveness analysis of a chemoresponse assay for treatment of patients with recurrent epithelial ovarian cancer, Victoria Plamadeala, Joseph L. Kelley, John K. Chan, Thomas C. Krivak, Michael J. Gabrin, Stacey L. Brower, Matthew A. Powell, Thomas J. Rutherford, and Robert L. Coleman

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A murine Niemann-Pick C1 I1061T knock-In model recapitulates the pathological features of the most prevalent human disease allele, Maria Praggastis, Brett Tortelli, Jessie Zhang, Hideji Fujiwara, Rohini Sidhu, Anita Chacko, Zhouji Chen, Jean E. Schaffer, Daniel S. Ory, and et al

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Converging evidence for the neuroanatomic basis of combinatorial semantics in the angular gyrus, Amy R. Price, Michael F. Bonner, Jonathan E. Peelle, and Murray Grossman

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Identification of hematomas in mild traumatic brain injury using an index of quantitative brain electrical activity, Leslie S. Prichep, Rosanne Naunheim, Jeffrey Bazarian, W. Andrew Mould, and Daniel Hanley

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Sustainability of evidence-based healthcare: Research agenda, methodological advances, and infrastructure support, Enola Proctor, Douglas Luke, Annaliese Calhoun, Curtis McMillen, Ross Brownson, Stacey McCrary, and Margaret Padek

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Oropouche virus infection and pathogenesis are restricted by MAVs, IRF-3, IRF-7, and type I interferon signaling pathways in nonmyeloid cells, Jose Luiz Proenca-Modena, Renata Sesti-Costa, Amelia K. Pinto, Justin M. Richner, Helen M. Lazear, Tiffany Lucas, Jennifer L. Hyde, and Michael S. Diamond

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A proliferation saturation index to predict radiation response and personalize radiotherapy fractionation, Sotiris Prokopiou, Eduardo G. Moros, Jan Poleszczuk, Jimmy Caudell, Javier F. Torres-Roca, Kujtim Latifi, Jae K. Lee, Robert Myerson, Louis B. Harrison, and Heiko Enderling

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Accurate age classification of 6 and 12 month-old infants based on resting-state functional connectivity magnetic resonance imaging data, John R. Pruett Jr., Sridhar Kandala, Sarah Hoertel, Abraham Z. Snyder, Tomoyuki Nishino, Nico U.F. Dosenbach, Binyam Nardos, Babatunde Adeyemo, Kelly N. Botteron, Robert C. McKinstry, John N. Constantino, Steven E. Petersen, Bradley L. Schlaggar, and et al

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Real-Time PCR assay for detection and differentiation of Shiga toxin-producing Escherichia coli from clinical samples, Xuan Qin, Eileen J. Klein, Emmanouil Galanakis, Anita A. Thomas, Jennifer R. Stapp, Shannon Rich, Anne Marie Buccat, and Phillip I. Tarr

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Influence of physical education on moderate-to-vigorous physical activity of urban public school children in St. Louis, Missouri, 2011–2014, Susan B. Racette, Tiffany C. Dill, M. Leanne White, Jacqueline C. Castillo, Mary L. Uhrich, Cindi L. Inman, Nicholas C. DuPont, and B. Ruth Clark

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CarD stabilizes mycobacterial open complexes via a two-tiered kinetic mechanism, Jayan Rammohan, Ana Ruiz Manzano, Ashley L. Garner, Christina L. Stallings, and Eric A. Galburt

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Using segmented regression analysis of interrupted time series data to assess colonoscopy quality outcomes of a web-enhanced implementation toolkit to support evidence-based practices for bowel preparation: A study protocol, Alex T. Ramsey, Julia Maki, Beth Prusaczyk, Yan Yan, Jean Wang, and Rebecca Lobb

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Provider-agency fit in substance abuse treatment organizations: Implications for learning climate, morale, and evidence-based practice implementation, Alex T. Ramsey, Carissa van den Berk-Clark, and David A. Patterson Silver Wolf (Adelvunegv Waya)

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Seminoma presenting as renal mass, inferior vena caval thrombus, and regressed testicular mass, Valary T. Raup, Michael H. Johnson, Jonathan R. Weese, Ian S. Hagemann, Stephen D. Marshall, and Steven B. Brandes

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Association of functional polymorphisms from brain-derived neurotrophic factor and serotonin-related genes with depressive symptoms after a medical stressor in older adults, Kerri S. Rawson, David Dixon, Petra Nowotny, William M. Ricci, Ellen F. Binder, Thomas Rodebaugh, Leah Wendleton, Peter Dore, and Eric J. Lenze

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Correlation of foraminal area and response to cervical nerve root injections, Wilson Z. Ray, Syed Akbari, Lubdha M. Shah, and Erica Bisson

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Fetal-to-maternal signaling to initiate parturition, Erin L. Reinl and Sarah K. England

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Function and postnatal changes of dural afferent fibers expressing TRPM8 channels, Lynn Ren, Ajay Dhaka, and Yu-Qing Cao

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IFIT1 differentially interferes with translation and replication of alphavirus genomes and promotes induction of type I interferon, Josephine M. Reynaud, Dal Young Kim, Svetlana Atasheva, Aliaksandra Rasalouskaya, James P. White, Michael S. Diamond, Scott C. Weaver, Elena I. Frolova, and Ilya Frolov

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Variability in the practice of fertility preservation for patients with cancer, Kasey A. Reynolds, Natalia M. Grindler, Julie S. Rhee, Amber R. Cooper, Valerie S. Ratts, Kenneth R. Carson, and Emily S. Jungheim

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What's new in Orthopaedic Trauma, William M. Ricci, James C. Black, Christopher M. McAndrew, and Michael J. Gardner

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Familiality and SNP heritability of age at onset and episodicity in major depressive disorder, J. P. Rice and et al

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A modular system of DNA enhancer elements mediates tissue-specific activation of transcription by high dietary zinc in C. elegans, Hyun Cheol Roh, Ivan Dimitrov, Krupa Deshmukh, Guoyan Zhao, Kurt Warnhoff, Daniel Cabrera, Wendy Tsai, and Kerry Kornfeld

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Sexual selection and cancer biology, Joshua B. Rubin

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Novel genetic locus implicated for HIV-1 acquisition with putative regulatory links to HIV replication and infectivity: A genome-wide association study, Nancy L. Saccone, John P. Rice, Laura J. Bierut, and et al

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Examination of the enterotoxigenic Escherichia coli population structure during human infection, Jason W. Sahl, Jeticia R. Sistrunk, Claire M. Fraser, Erin Hine, Nabilah Baby, Yasmin Begum, Qingwei Luo, Alaullah Sheikh, Firdausi Qadri, James M. Fleckenstein, and David A. Rasko

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Secreted CLCA1 modulates TMEM16A to activate Ca2+-dependent chloride currents in human cells, Monica Sala-Rabanal, Zeynep Yurtsever, Colin G. Nichols, and Tom J. Brett

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Use of culturally focused theoretical frameworks for adapting diabetes prevention programs: A qualitative review, Vetta L. Sanders Thompson, Michelle Johnson-Jennings, Ana A. Baumann, and Enola Proctor

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Are movement disorders and sensorimotor injuries pathologic synergies? When normal multi-joint movement synergies become pathologic, Marco Santello and Catherine E. Lang

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Sensitivity and kinetics of signal transmission at the first visual synapse differentially impact visually-guided behavior, Ignacio Sarria, Johan Pahlberg, Yan Cao, Alexander V. Kolesnikov, Vladimir J. Kefalov, Alapakkam P. Sampath, and Kirill A. Martemyanov

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Architectural and biochemical adaptations in skeletal muscle and bone following rotator cuff injury in a rat model, Eugene J. Sato, Megan L. Killian, Anthony J. Choi, Evie Lin, Alexander D. Choo, Ana E. Rodriguez-Soto, Chanteak T. Lim, Stavros Thomopoulos, Leesa M. Galatz, and Samuel R. Ward

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Deficiency of Prdm13, a dorsomedial hypothalamus-enriched gene, mimics age-associated changes in sleep quality and adiposity, Akiko Satoh, Cynthia S. Brace, Nick Rensing, and Shin-ichiro Imai

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Nab-paclitaxel-based compared to docetaxel-based induction chemotherapy regimens for locally advanced squamous cell carcinoma of the head and neck, Amy Schell, Jessica Ley, Ningying Wu, Kathryn Trinkaus, Tanya Marya Wildes, Loren Michel, Wade Thorstad, Hiram Gay, James Lewis, Jason Rich, Jason Diaz, Randal C. Paniello, Brian Nussenbaum, and Douglas R. Adkins

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Region-specific variation in the properties of skeletal adipocytes reveals regulated and constitutive marrow adipose tissues, Erica L. Scheller and et al.

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The mitochondria in diabetic heart failure: From pathogenesis to therapeutic promise, Joel D. Schilling

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Autosomal dominant Alzheimer disease: A unique resource to study CSF biomarker changes in preclinical AD, Suzanne Elizabeth Schindler and Anne M. Fagan

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The utility of Google Trends data to examine interest in cancer screening, Mario Schootman, Aroona H. Toor, Patricia A. Cavazos-Rehg, Donna B. Jeffe, Amy McQueen, J. Eberth, and Nicholas O. Davidson

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Uropathogenic Escherichia coli superinfection enhances the severity of mouse bladder infection, Drew J. Schwartz, Matt S. Conover, Thomas J. Hannan, and Scott J. Hultgren

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REDHORSE-REcombination and Double crossover detection in Haploid Organisms using next-geneRation SEquencing data, Jahangheer S. Shaik, Asis Khan, Stephen M. Beverley, and L. David Sibley

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Voluntary exercise training: Analysis of mice in uninjured, inflammatory, and nerve-injured pain states, Tyler D. Sheahan, Bryan A. Copits, Judith P. Golden, and Robert W. Gereau IV

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Selective blockade of interferon-α and -β reveals their non-redundant functions in a mouse model of West Nile virus infection, Kathleen C. F. Sheehan, Helen M. Lazear, Michael S. Diamond, and Robert D. Schreiber

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Adenovirus vector expressing Stx1/Stx2-neutralizing agent protects piglets infected with Escherichia coli O157: H7 against fatal systemic intoxication, Abhineet S. Sheoran, Igor P. Dmitriev, Elena A. Kashentseva, Ocean Cohen, Jean Mukherjee, Michelle Debatis, Jonathan Schearer, Jacqueline M. Tremblay, Gillian Beamer, David T. Curiel, Charles B. Shoemaker, and Saul Tzipori

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Prognostic capabilities of coronary computed tomographic angiography before non-cardiac surgery: Prospective cohort study, Tej Sheth, Matthew Chan, Craig Butler, Benjamin Chow, Vikas Tandon, Peter Nagele, Ayesha Mitha, Marko Mrkobrada, Wojciech Szczeklik, Yang Faridah, Bruce Biccard, Lori K. Stewart, Diane Heels-Ansdell, P. J. Devereaux, and Coronary Computed Tomographic Angiography and Vascular Events in Noncardiac Surgery Patients Cohort Evaluation (Coronary CTA VISION) Study Investigators

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Dynamic changes in the subgingival microbiome and their potential for diagnosis and prognosis of periodontitis, Baochen Shi, Michaela Chang, John Martin, Makedonka Mitreva, Renate Lux, Perry Klokkevold, Erica Sodergren, George M. Weinstock, Susan K. Haake, and Huiying Li

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WU polyomavirus in respiratory epithelial cells from lung transplant patient with job syndrome, Erica A. Siebrasse, Nang L. Nguyen, Annie Wang, David Wang, Diana V. Pastrana, Mark J. Roth, Steven M. Holland, Alexandra F. Freeman, Christopher B. Buck, and John McDyer

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Deconvoluting heme biosynthesis to target blood-stage malaria parasites, Paul A. Sigala, Jan R. Crowley, Jeffrey P. Henderson, and Daniel E. Goldberg

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Clinical effectiveness of a sedation protocol minimizing benzodiazepine infusions and favoring early dexmedetomidine: A before-after study, Lee P. Skrupky, Anne M. Drewry, Brian Wessman, R. Ryan Field, Richard E. Fagley, Linda Varghese, Angela Lieu, Joshua Olatunde, Scott T. Micek, Marin H. Kollef, and Walter A. Boyle

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Loss of local astrocyte support disrupts action potential propagation and glutamate release synchrony from unmyelinated hippocampal axon terminals in vitro, Courtney Sobieski, Xiaoping Jiang, Devon C. Crawford, and Steven Mennerick

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A case of squamous cell carcinoma of the skin due to the molecularly confirmed Lynch Syndrome, Steven Sorscher

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Exome sequencing for mucolipidosis III: Detection of a novel GNPTAB gene mutation in a patient with a very mild phenotype, F. Sperb-Ludwig, T. Alegra, R. V. Velho, N. Ludwig, C. A. Kim, F. Kok, J. P. Kitajima, E. van Meel, S. Kornfeld, M. G. Burin, and I. V.D. Schwartz

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Precision medicine to improve use of bleeding avoidance strategies and reduce bleeding in patients undergoing percutaneous coronary intervention: Prospective cohort study before and after implementation of personalized bleeding risks, John A. Spertus, Carole Decker, Elizabeth Gialde, Philip G. Jones, Edward J. McNulty, Richard Bach, and Adnan K. Chhatriwalla

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Exome sequencing of case-unaffected-parents trios reveals recessive and de novo genetic variants in sporadic ALS, Karyn Meltz Steinberg, Bing Yu, Daniel C. Koboldt, Elaine R. Mardis, and Roger Pamphlett

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Burden of disease variants in participants of the Long Life Family Study, Meredith Stevenson, Harold Bae, Nicole Schupf, Stacy Andersen, Qunyuan Zhang, Thomas Perls, and Paola Sebastiani

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Additive global cerebral blood flow normalization in arterial spin labeling perfusion imaging, Stephanie B. Stewart, Jonathan M. Koller, Meghan C. Campbell, Joel S. Perlmutter, and Kevin J. Black

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Cooperation between Noncanonical Ras Network Mutations, Edward C. Stites, Paul C. Trampont, Lisa B. Haney, Scott F. Walk, and Kodi S. Ravichandran

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Enhancing workplace wellness efforts to reduce obesity: A qualitative study of low-wage workers in St Louis, Missouri, 2013-2014, Jaime Strickland, Amy A. Eyler, Jason Q. Purnell, Anna M. Kinghorn, Cynthia Herrick, and Bradley A. Evanoff

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Worksite influences on obesogenic behaviors in low-wage workers in St Louis, Missouri, 2013-2014, Jaime R. Strickland, Galen Pizzorno, Anna M. Kinghorn, and Bradley A. Evanoff

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Synthesis, characterization, and preclinical validation of a PET radiopharmaceutical for interrogating Aβ (β-amyloid) plaques in Alzheimer’s disease, Guruswami S.M. Sundaram, Dhruva Dhavale, Julie L. Prior, Jothilingam Sivapackiam, Richard Laforest, Paul Kotzbauer, and Vijay Sharma

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Role of visual and non-visual cues in constructing a rotation-invariant representation of heading in parietal cortex, Adhira Sunkara, Gregory C. DeAngelis, and Dora E. Angelaki

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Quantitative amyloid imaging using image-derived arterial input function, Yi Su, Tyler M. Blazey, Abraham Z. Snyder, Marcus E. Raichle, Russ C. Hornbeck, Patricia Aldea, John C. Morris, and Tammie L. S. Benzinger

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Securely measuring the overlap between private datasets with cryptosets, S. Joshua Swamidass, Matthew Matlock, and Leon Rozenblit

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Workplace social and organizational environments and healthy-weight behaviors, Rachel G. Tabak, J. Aaron Hipp, Christine M. Marx, and Ross C. Brownson

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Taspase1-dependent TFIIA cleavage coordinates head morphogenesis by limiting Cdkn2a locus transcription, Shugaku Takeda, Satoru Sasagawa, Toshinao Oyama, Adam C. Searleman, Todd D. Westergard, Emily H. Cheng, and James J. Hsieh

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Characterization of herpes simplex virus 2 primary microRNA transcript regulation, Shuang Tang, Marta Bosch-Marce, Amita Patel, Todd P. Margolis, and Philip R. Krause

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Characterization of HSV-2 primary miRNA transcript regulation, Shuang Tang, Marta Bosch-Marce, Amita Patel, Todd P. Margolis, and Philip R. Krause

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Role of RNase H1 in DNA repair: Removal of single ribonucleotide misincorporated into DNA in collaboration with RNase H2, Elias Tannous, Eiko Kanaya, and Shigenori Kanaya

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Transcriptomic-wide discovery of direct and indirect HuR RNA targets in activated CD4+ T cells, Patsharaporn Techasintana, J. Wade Davis, Matthew M. Gubin, Joseph D. Magee, and Ulus Atasoy

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DNA2 drives processing and restart of reversed replication forks in human cells, Saravanabhavan Thangavel, Matteo Berti, Maryna Levikova, Cosimo Pinto, Shivasankari Gomathinayagam, Marko Vujanovic, Ralph Zellweger, Hayley Moore, Eu Han Lee, Eric A. Hendrickson, Petr Cejka, Sheila Stewart, Massimo Lopes, and Alessandro Vindigni

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DNA2 drives processing and restart of reversed replication forks in human cells, Saravanabhavan Thangavel, Matteo Berti, Maryna Levikova, Cosimo Pinto, Shivasankari Gomathinayagam, Marko Vujanovic, Ralph Zellweger, Hayley Moore, Eu Han Lee, Eric A. Hendrickson, Petr Cejka, Sheila Stewart, Massimo Lopes, and Alessandro Vindigni

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Genetically identified suppressed-by-contrast retinal ganglion cells reliably signal self-generated visual stimuli, Nai-Wen Tien, James T. Pearson, Charles R. Heller, Jay Demas, and Daniel Kerschensteiner