The Open Access Publications collection contains peer-reviewed articles authored by Washington University School of Medicine faculty that have been published in open access journals or authorized by the publishers for open access availability. Open access works are generally defined as being publicly available online and free of most licensing and copyright restrictions. The Bernard Becker Medical Library maintains this collection in support of Washington University’s commitment to the principles of open access publishing and making the scholarly work and research results of our faculty as widely and easily available as possible.

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Submissions from 2014

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Human cytomegalovirus US28 facilitates cell-to-cell viral dissemination, Vanessa M. Noriega, Thomas J. Gardner, Veronika Redmann, Gerold Bongers, Sergio A. Lira, and Domenico Tortorella

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DNA polymerases ζ and Rev1 mediate error-prone bypass of non-B DNA structures, Matthew R. Northam, Elizabeth A. Moore, Tony M. Mertz, Sara K. Binz, Carrie M. Stith, Elena I. Stepchenkova, Kathern L. Wendt, Peter M. J. Burgers, and Polina V. Scherbakova

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Finished sequence and assembly of the DUF1220-rich 1q21 region using a haploid human genome, Majesta O'Bleness, Veronica B. Searles, C. Michael Dickens, David Astling, Derek Albracht, Angel C.Y. Mak, Yvonne Y.Y. Lai, Chin Lin, Catherine Chu, Tina Graves, Pui-Yan Kwok, Richard K. Wilson, and James M. Sikela

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Key issues and opportunities in the evolving health-care marketplace: AOA critical issues, Kristin Olds Glavin, Daniel B. Murrey, Joel C. Porter, Donald Brunn, and Rick W. Wright

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Subcellular optogenetic inhibition of G proteins generates signaling gradients and cell migration, Patrick R. O'Neill and N. Gautam

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Simultaneous bilateral or unilateral carpal tunnel release? A prospective cohort study of early outcomes and limitations, Daniel A. Osei, Ryan P. Calfee, Jeffrey G. Stepan, Martin I. Boyer, Charles A. Goldfarb, and Richard H. Gelberman

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Defining NELF-E RNA binding in HIV-1 and promoter-proximal pause regions, John M. Pagano, Hojoong Kwak, Colin T. Waters, Rebekka O. Sprouse, Brian S. White, Abdullah Ozer, Kylan Szeto, David Shalloway, Harold G. Craighead, and John T. Lis

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Chikungunya viruses that escape monoclonal antibody therapy are clinically attenuated, stable, and not purified in mosquitoes, Pankaj Pal, Julie M. Fox, Michael S. Diamond, and et al

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Anti-angiogenesis therapy in the Vx2 rabbit cancer model with a lipase-cleavable Sn 2 taxane phospholipid prodrug using αvβ3-targeted theranostic nanoparticles, Dipanjan Pan, Anne H. Schmieder, Kezheng Wang, Xiaoxia Yang, Angana Senpan, Grace Cui, Kendall Killgore, Benjamin Kim, John S. Allen, Huiying Zhang, Shelton D. Caruthers, Baozhong Shen, Samuel A. Wickline, and Gregory M. Lanza

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Blocking the apoE/Aβ interaction ameliorates Aβ-related pathology in APOE ε2 and ε4 targeted replacement Alzheimer model mice, Joanna E. Pankiewicz, Maitea Guridi, Jungsu Kim, Ayodeji A. Asuni, Sandrine Sanchez, Patrick M. Sullivan, David M. Holtzman, and Martin J. Sadowski

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Tumor-induced STAT3 activation in monocytic myeloid-derived suppressor cells enhances stemness and mesenchymal properties in human pancreatic cancer, Roheena Z. Panni, Dominic E. Sanford, Brian A. Belt, Jonathan B. Mitchem, Lori A. Worley, Brian D. Goetz, Pinku Mukherjee, Andrea Wang-Gillam, Daniel C. Link, David G. DeNardo, S. Peter Goedegebuure, and David C. Linehan

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Inputs drive cell phenotype variability, James Park, Anthony Brureau, Kate Kernan, Alexandria Starks, Sonali Gulati, Babatunde Ogunnaike, James Schwaber, and Rajanikanth Vadigepalli

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The effect of dietary fat intake on hepatic gene expression in LG/J AND SM/J mice, Charlyn G. Partridge, Gloria L. Fawcett, Bing Wang, Clay F. Semenkovich, and James M. Cheverud

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Bioelectric signaling regulates size in zebrafish fins, Simon Perathoner, Jacob M. Daane, Ulrike Henrion, Guiscard Seebohm, Charles W. Higdon, Stephen L. Johnson, Christiane Nusslein-Volhard, and Matthew P. Harris

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Clinical and biomarker changes in premanifest Huntington disease show trial feasibility: A decade of the PREDICT-HD study, Joel S. Perlmutter, Stacey Barton, Shineeka Kaye Smith, and et al

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Gait-related brain activity in people with Parkinson disease with freezing of gait, Daniel S. Peterson, Kristen A. Pickett, Ryan Duncan, Joel Perlmutter, and Gammon M. Earhart

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Increased iron sequestration in alveolar macrophages in chronic obtructive pulmonary disease, Quentin Philippot, Gaetan Deslee, Tracy L. Adair-Kirk, Jason C. Woods, Derek Byers, Susan Conradi, Sandra Dury, Jeanne Marie Perotin, Francois Lebargy, Christelle Cassan, Richard Le Naour, Michael J. Holtzman, and Richard A. Pierce

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Deficient IFN signaling by myeloid cells leads to MAVS-dependent virus-induced sepsis, Amelia K. Pinto, Hilario J. Ramos, Xiaobo Wu, Shilpa Aggarwal, Bimmi Shrestha, Matthew Gorman, Kristin Y. Kim, Mehul S. Suthar, John P. Atkinson, Michael Gale Jr., and Michael S. Diamond

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Routine testing for anaerobic bacteria in cerebrospinal fluid cultures improves recovery of clinically significant pathogens, Meredith E. Pittman, Benjamin S. Thomas, Meghan A. Wallace, Carol J. Weber, and Carey-Ann D. Burnham

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Streptococcus pyogenes polymyxin B-resistant mutants display enhanced exportal integrity, Gary C. Port, Luis A. Vega, Andrew B. Nylander, and Michael G. Caparon

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Hippocampal long-term potentiation is disrupted during expression and extinction but is restored after reinstatement of morphine place preference, George S. Portugal, Ream Al-Hasani, Amanda K. Fakira, Jose L. Gonzalez-Romero, Zare Melyan, Jordan G. McCall, Michael R. Bruchas, and Jose A. Moron

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Molecularly targeted therapies in multiple myeloma, Pilar de la Puente, Barbara Muz, Feda Azab, Micah Luderer, and Abdel Kareem Azab

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Intracellular mGluR5 can mediate synaptic plasticity in the hippocampus, Carolyn A. Purgert, Yukitoshi Izumi, Yuh-Jin I. Jong, Vikas Kumar, Charles F. Zorumski, and Karen L. O'Malley

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Single-cell resolution imaging of retinal ganglion cell apoptosis in vivo using a cell-penetrating caspase-activatable peptide probe, Xudong Qiu, James R. Johnson, Bradley S. Wilson, Seth T. Gammon, David Piwnica-Worms, and Edward M. Barnett

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Diffusion tensor imaging in children with unilateral hearing loss: A pilot study, Tara Rachakonda, Joshua S. Shimony, Rebecca S. Coalson, and Judith E.C. Lieu

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AKT inhibitors promote cell death in cervical cancer through disruption of mTOR signaling and glucose uptake, Ramachandran Rashmi, Carl DeSelm, Cynthia Helms, Anne Bowcock, Buck E. Rogers, Janet Rader, Perry W. Grigsby, and Julie K. Schwarz

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Francisella tularensis Schu S4 lipopolysaccharide core sugar and o-antigen mutants are attenuated in a mouse model of tularemia, Jed A. Rasmussen, Deborah M.B. Post, Bradford W. Gibson, Stephen R. Lindemann, Michael A. Apicella, David K. Meyerholz, and Bradley D. Jones

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IL-15 deficient Tax mice reveal a role for IL-1α in tumor immunity, Daniel A. Rauch, John C. Harding, and Lee Ratner

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Management of anticoagulant-related intracranial hemorrhage: An evidence-based review, Bappaditya Ray and Salah G. Keyrouz

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Illustrated techniques for performing the Cox-Maze IV procedure through a right mini-thoracotomy, Jason O. Robertson, Lindsey L. Saint, Jeremy E. Leidenfrost, and Ralph J. Damiano Jr.

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Utilizing cytokines to function-enable human NK cells for the immunotherapy of cancer, Rizwan Romee, Jeffrey W. Leong, and Todd A. Fehniger

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Genome-wide tissue-specific gene expression, co-expression and regulation of co-expressed genes in adult nematode Ascaris suum, Bruce A. Rosa, Douglas P. Jasmer, and Makedonka Mitreva

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The role of neutrophil myeloperoxidase in models of lung tumor development, Amy Rymaszewski, Everett Tate, Joannes P. Yimbesalu, Andrew E. Gelman, Jason A. Jarzembowski, Hao Zhang, Kirkwood A. Pritchard Jr., and Haris G. Vikis

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How I do it: Minimally invasive Cox-Maze IV procedure, Lindsey L. Saint, Christopher P. Lawrance, Jeremy E. Leidenfrost, Jason O. Roberston, and Ralph J. Damiano Jr.

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Hepatitis C virus-induced changes in microRNA 107 (miRNA-107) and miRNA-449a modulate CCL2 by targeting the interleukin-6 receptor complex in hepatitis, Nayan J. Sarma, Venkataswarup Tiriveedhi, Jeffrey S. Crippin, William C. Chapman, and Thalachallour Mohanakumar

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Targeting hepatic glycerolipid synthesis and turnover to treat fatty liver disease, George G. Schweitzer and Brian N. Finck

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Association of comorbidity burden with abnormal cardiac mechanics: Findings from the HyperGEN study, Senthil Selvaraj, Frank G. Aguilar, Eva E. Martinez, Lauren Beussink, Kwang-Youn A. Kim, Jie Peng, Laura Rasmussen-Torvik, Jin Sha, Marguerite R. Irvin, C. Charles Gu, Cora E. Lewis, Steven C. Hunt, Donna K. Arnett, and Sanjiv J. Shah

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Memory accumulation mechanisms in human cortex are independent of motor intentions, Carlo Sestieri, Annalisa Tosoni, Valeria Mignogna, Mark P. McAvoy, Gordon L. Shulman, Maurizio Corbetta, and Gian Luca Romani

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Endoluminal Negative-Pressure Therapy for Preventing Rectal Anastomotic Leaks: A Pilot Study in a Pig Model, Amber L. Shada, Laura H. Rosenberger, Mark J. Mentrikoski, Michael A. Silva, Sanford H. Feldman, and Daniel E. Kleiner

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Absence of calcium‐independent phospholipase A2β impairs platelet‐activating factor production and inflammatory cell recruitment in Trypanosoma cruzi‐infected endothelial cells, Janhavi Sharma, Christopher S. Eickhoff, Daniel F. Hoft, John O. Marentette, John Turk, and Jane McHowat

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Kinases and pseudokinases: Lessons from RAF, Andrey S. Shaw, Alexandr P. Kornev, Jiancheng Hu, Lalima G. Ahuja, and Susan S. Taylor

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Efficient gene disruption in diverse strains of Toxoplasma gondii using CRISPR/CAS9, Bang Shen, Kevin M. Brown, Tobie D. Lee, and L. David Sibley

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SIRT6 is required for normal retinal function, Dafne M. Silberman, Kenneth Ross, Pablo H. Sande, Shunsuke Kubota, Sridhar Ramaswamy, Rajendra S. Apte, and Raul Mostoslavsky

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Spike-timing computation properties of a feed-forward neural network model, Drew B. Sinha, Noah M. Ledbetter, and Dennis L. Barbour

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Patient age is related to decision-making, treatment selection, and perceived quality of life in breast cancer survivors, Terence T. Sio, Kenneth Chang, Ritujith Jayakrishnan, Difu Wu, Mary Politi, Dominique Malacarne, James Saletnik, and Maureen Chung

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Nutraceutical intervention improves older adults' cognitive functioning, Brent J. Small, Kerri S. Rawson, Christina Martin, Sarah L. Eisel, Cyndy D. Sanberg, Cathy L. McEvoy, Paul R. Sanberg, Douglas Shytle, Jun Tan, and Paula C. Bickford

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Multiple dietary supplements do not affect metabolic and cardio-vascular health, Andreea Soare, Edward P. Weiss, John O. Holloszy, and Luigi Fontana

Tissue-resident natural killer (NK) cells are cell lineages distinct from thymic and conventional splenic NK cells, Dorothy K. Sojka, Beatrice Plougastel-Douglas, Liping Yang, Melissa A. Pak-Wittel, Maxim N. Artyomov, Yulia Ivanova, Chao Zhong, Julie M. Chase, Paul B. Rothman, Jenny Yu, Joan K. Riley, Jinfang Zhu, Zhigang Tian, and Wayne M. Yokoyama

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Dynamic radiographic criteria for detecting pseudarthrosis following anterior cervical arthrodesis, Kwang-Sup Song, Chaiwat Piyaskulkaew, Tapanut Chuntarapas, Jacob M. Buchowski, Han Jo Kim, Moon Soo Park, Hyun Kang, and K. Daniel Riew

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Unexpected abrupt increase in left ventricular assist device thrombosis, Randall C. Starling, Nader Moazami, Scott C. Silvestry, Gregory Ewald, Joseph G. Rogers, Carmelo A. Milano, J Eduardo Rame, Michael A. Acker, Eugene H. Blackstone, John Ehrlinger, Lucy Thuita, Maria M. Mountis, Edward G. Soltesz, Bruce W. Lytle, and Nicholas G. Smedira

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Extensive diversity of prion strains is defined by differential chaperone interactions and distinct amyloidogenic regions, Kevin C. Stein and Heather L. True

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Expression of nampt in hippocampal and cortical excitatory neurons is critical for cognitive function, Liana Roberts Stein, David F. Wozniak, Joshua T. Dearborn, Shunsuke Kubota, Rajendra S. Apte, Yukitoshi Izumi, Charles F. Zorumski, and Shin-ichiro Imai

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Impact of radiation therapy on survival in patients with triple‑negative breast cancer, Lauren T. Steward, Feng Gao, Marie A. Taylor, and Julie A. Margenthaler

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Subtelomeric CTCF and cohesin binding site organization using improved subtelomere assemblies and a novel annotation pipeline, Nicholas Stong, Zhong Deng, Ravi Gupta, Sufen Hu, Shiela Paul, Amber K. Weiner, Evan E. Eichler, Tina Graves, Catrina C. Fronick, Laura Courtney, Richard K. Wilson, Paul M. Lieberman, Ramana V. Davuluri, and Harold Riethman

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The relation of plasmacytoid dendritic cells (pDCs) and regulatory t-cells (Tregs) with HPV persistence in HIV-Infected and HIV-Uninfected women, Howard D. Strickler, Jeffrey Martinson, L. Stewart Massad, Seema Desai, Xianhong Xie, Robert D. Burk, Kathryn Anastos, Howard Minkoff, Xianan Xue, Gypsyamber D'Souza, Alexandra M. Levine, Christine Colie, Heather Watts, Joel M. Palefsky, and Alan Landay

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Prenatal tobacco smoke exposure is associated with childhood DNA CpG methylation, Robert Strunk and et al

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Single nucleotide variants in transcription factors associate more tightly with phenotype than with gene expression, Priya Sudarsanam and Barak A. Cohen

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Mitochondrial dysfunction induces Sarm1-dependent cell death in sensory neurons, Daniel W. Summers, Aaron DiAntonio, and Jeffrey Milbrandt

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TCAB1: A potential target for diagnosis and therapy of head and neck carcinomas, Chong-kui Sun, Xiao-bo Luo, Ya-ping Gou, Ling Hu, Kun Wang, Chao Li, Zhen-ting Xiang, Ping Zhang, Xiang-li Kong, Chao-liang Zhang, Qin Yang, Jing Li, Li-ying Xiao, Yan Li, and Qian-ming Chen

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Phosphorylation of ribosomal protein S6 confers PARP inhibitor resistance in BRCA1-deficient cancers, Chong-kui Sun, Fan Zhang, Tao Xiang, Qianming Chen, Tej K. Pandita, Yuping Huang, Mickey C T Hu, and Qin Yang

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Whole genome sequence analysis of the simulated systolic blood pressure in Genetic Analysis Workshop 18 family data: Long-term average and collapsing methods, Yun Ju Sung, Jacob Basson, and Dabeeru C. Rao

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Comparison of two methods for analysis of gene-environment interactions in longitudinal family data: The Framingham heart study, Yun Ju Sung, Jeannette Simino, Rezart Kume, Jacob Basson, Karen Schwander, and D. C. Rao

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Congenitally acquired persistent lymphocytic choriomeningitis viral infection reduces neuronal progenitor pools in the adult hippocampus and subventricular zone, Tony Sun, Michael J. Vasek, and Robyn S. Klein

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Constitutive activation of IKK2/NF-κB impairs osteogenesis and skeletal development, Gaurav Swarnkar, Kaihua Zhang, Gabriel Mbalaviele, Fanxin Long, and Yousef Abu-Amer

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Genome sequence of Escherichia coli O157:H7 strain 2886-75, associated with the first reported case of human infection in the United States, Phillip I. Tarr and et al

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The role of muscle loading on bone (re)modeling at the developing enthesis, Alexander M. Tatara, Justin H. Lipner, Rosalina Das, H. Mike Kim, Nikunj Patel, Eleni Ntouvali, Matthew J. Silva, and Stavros Thomopoulos

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Alterations in the optic radiations of very preterm children - Perinatal predictors and relationships with visual outcomes, Deanne K. Thompson, Dolly Thai, Claire E. Kelly, Alexander Leemans, Jacques-Donald Tournier, Michael J. Kean, Katherine J. Lee, Terrie E. Inder, Lex W. Doyle, Peter J. Anderson, and Rodney W. Hunt

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Using written narratives in public health practice: A creative writing perspective, Tess Thompson and Matthew W. Kreuter

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Mechanistically distinct mouse models for CRX-associated retinopathy, Nicholas M. Tran, Alan Zhang, Xiaodong Zhang, Julie B. Huecker, Anne K. Hennig, and Shiming Chen

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Studies of inactivation mechanism of non-enveloped icosahedral virus by a visible ultrashort pulsed laser, Shaw-Wei D. Tsen, David H. Kingsley, Christian Poweleit, Samuel Achilefu, Douglas S. Soroka, T. C. Wu, and Kong-Thon Tsen

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Dysferlin mediates the cytoprotective effects of TRAF2 following myocardial ischemia reperfusion injury, Huei-Ping Tzeng, Sarah Evans, Feng Gao, Kari Chambers, Veli K. Topkara, Natarajan Sivasubramanian, Philip M. Barger, and Douglas L. Mann

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Species D human adenovirus type 9 exhibits better virus-spread ability for antitumor efficacy among alternative serotypes, Junji Uchino, David T. Curiel, and Hideyo Ugai

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Altered microglial response to Aβ plaques in APPPS1-21 mice heterozygous for TREM2, Jason D. Ulrich, Mary Beth Finn, Yaming Wang, Alice Shen, Thomas E. Mahan, Hong Jiang, Floy R. Stewart, Laura Piccio, Marco Colonna, and David M. Holtman

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Cryptococcus at work: Gene expression during human infection, Rajendra Upadhya, Maureen J. Donlin, and Jennifer K. Lodge

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Actin scaffolding by clathrin heavy chain is required for skeletal muscle sarcomere organization, Stéphane Vassilopoulos, Christel Gentil, Jeanne Lainé, Pierre-Olivier Buclez, Agathe Franck, Arnaud Ferry, Guillaume Précigout, Robyn Roth, John E. Heuser, Frances M. Brodsky, Luis Garcia, Gisèle Bonne, Thomas Voit, France Piétri-Rouxel, and Marc Bitoun

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Experimental infection of rhesus macaques and common marmosets with a European strain of West Nile virus, Babs E. Verstrepen, Zahra Fagrouch, Melanie van Heteren, Hester Buitendijk, Tom Haaksma, Niels Beenhakker, Giorgio Palu, Justin M. Richner, Michael S. Diamond, Willy M. Bogers, Luisa Barzon, Stefan Chabierski, Sebastian Ulbert, Ivanela Kondova, and Ernst J. Verschoor

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Expanding the direct HetR regulon in Anabaena sp. strain PCC 7120, Patrick Videau, Shuisong Ni, Orion S. Rivers, Blake Ushijima, Erik A. Feldmann, Loralyn M. Cozy, Michael A. Kennedy, and Sean M. Callahan

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Mitochondrial pyruvate carrier 2 hypomorphism in mice leads to defects in glucose-stimulated insulin secretion, Patrick A. Vigueira, Kyle S. McCommis, George G. Schweitzer, Maria S. Remedi, Kari T. Chambers, Xiaorong Fu, William G. McDonald, Serena L. Cole, Jerry R. Colca, Rolf F. Kletzien, Shawn C. Burgess, and Brian N. Finck

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Daily bathing with chlorhexidine-based soap and the prevention of Staphylococcus aureus transmission and infection, Melissa A. Viray, James C. Morley, Craig M. Coopersmith, Marin H. Kollef, Victoria J. Fraser, and David K. Warren

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Kinetochore-microtubule attachment throughout mitosis potentiated by the elongated stalk of the kinetochore kinesin CENP-E, Benjamin Vitre, Nikita Gudimchuk, Ranier Borda, Yumi Kim, John E. Heuser, Don W. Cleveland, and Ekaterina L. Grishchuk

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The VWFA: It's not just for words anymore, Alecia C. Vogel, Steven E. Petersen, and Bradley L. Schlaggar

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PI3Kδ inhibition by idelalisib in patients with relapsed indolent lymphoma, Nina D. Wagner-Johnston and et al

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Identification of Alternative Transcripts Encoding the Essential Murine Gammaherpesvirus Lytic Transactivator RTA, Brian S. Wakeman, L. Steven Johnson, Clinton R. Paden, Kathleen S. Gray, Herbert W. Virgin, and Samuel H. Speck

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Reactivation of multiple viruses in patients with sepsis, Andrew H. Walton, Jared T. Muenzer, David Rasche, Jonathan S. Boomer, Bryan Sato, Bernard H. Brownstein, Alexandre Pachot, Terrence L. Brooks, Elena Deych, William D. Shannon, Jonathan M. Green, Gregory A. Storch, and Richard S. Hotchkiss

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Expert recommendations for implementing change (ERIC): Protocol for a mixed methods study, Thomas J. Waltz, Byron J. Powell, Matthew J. Chinman, Jeffrey L. Smith, Monica M. Matthieu, Enola K. Proctor, Laura J. Damschroder, and JoAnn E. Kirchner

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NOD2 is dispensable for ATG16L1 deficiency-mediated resistance to urinary tract infection, Caihong Wang, Xuejun Yuan, Emly Ma, Graziella R. Mendonsa, Theo R. Plantinga, Lambertus A. Kiemeney, Sita H. Vermeulen, and Indira U. Mysorekar

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Filifactor alocis infection and inflammatory responses in the mouse subcutaneous chamber model, Qian Wang, Ravi Jotwani, Junyl Le, Jennifer L. Krauss, Jan Potempa, Susan C. Coventry, Silvia M. Urlarte, and Richard J. Lamont

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Adjuvant-specific regulation of long-term antibody responses by ZBTB20, Yinan Wang and Deepta Bhattacharya

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Cryptococcus neoformans Dual GDP-mannose transporters and their role in biology and virulence, Zhuo A. Wang, Cara L. Griffith, Michael L. Skowyra, Nichole Salinas, Matthew Williams, Ezekiel J. Maier, Stacey R. Gish, Hong Liu, Michael R. Brent, and Tamara L. Doering

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Whole-genome sequencing of Salmonella enterica subsp. enterica serovar Cubana strains isolated from agricultural sources, George Weinstock and et al

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Microbial community dynamics and stability during an ammonia-induced shift to syntrophic acetate oxidation, Jeffrey J. Werner, Marcelo L. Garcia, Sarah D. Perkins, Kevin E. Yarasheski, Samuel R. Smith, Brian D. Muegge, Frank J. Stadermann, Christopher M. DeRito, Christine Floss, Eugene L. Madsen, Jeffrey I. Gordon, and Largus T. Angenent

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Septic arthritis of a native knee joint due to Corynebacterium striatum, Lars F. Westblade, Farah Shams, Scott Duong, Oosman Tariq, Alan Bulbin, Dava Klirsfeld, Wei Zhen, Smita Sakaria, Bradley A. Ford, Carey-Ann D. Burnham, and Christine C. Ginnochio

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Integrated RNA and DNA sequencing improves mutation detection in low purity tumors, Matthew D. Wilkerson, Christopher R. Cabanski, Wei Sun, Katherine A. Hoadley, Vonn Walter, Lisle E. Mose, Melissa A. Troester, Peter S. Hammerman, Joel S. Parker, Charles M. Perou, and D. Neil Hayes

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Chemokines in the balance: Maintenance of homeostasis and protection at CNS barriers, Jessica L. Williams, David W. Holman, and Robyn S. Klein

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Targeting CXCR7/ACKR3 as a therapeutic strategy to promote remyelination in the adult central nervous system, Jessica L. Williams, Jigisha R. Patel, Brian P. Daniels, and Robyn S. Klein

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An fMRI study of the influence of a history of substance abuse on working memory-related brain activation in schizophrenia, Jessica A. Wojtalik and Deanna M. Barch

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A meta-Analysis revealed insights into the sources, conservation and impact of microRNA 5′-isoforms in four model species, Jing Xia and Weixiong Zhang

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Enhancing astrocytic lysosome biogenesis facilitates Aβ clearance and attenuates amyloid plaque pathogenesis, Qingli Xiao, Ping Yan, Xiucui Ma, Haiyan Liu, Ronaldo Perez, Alec Zhu, Ernesto Gonzales, Jack M. Burchett, Dorothy R. Schuler, John R. Cirrito, Abhinav Diwan, and Jin-Moo Lee

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Mast cell leukemia with prolonged survival on PKC412/midostaurin, Xiangdong Xu, Friederike H. Kreisel, John L. Frater, and Anjum Hassan

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Cell type-specific expression analysis to identify putative cellular mechanisms for neurogenetic disorders, Xiaoxiao Xu, Alan B. Wells, David R. O'Brien, Arye Nehorai, and Joseph D. Dougherty