The Open Access Publications collection contains peer-reviewed articles authored by Washington University School of Medicine faculty that have been published in open access journals or authorized by the publishers for open access availability. Open access works are generally defined as being publicly available online and free of most licensing and copyright restrictions. The Bernard Becker Medical Library maintains this collection in support of Washington University’s commitment to the principles of open access publishing and making the scholarly work and research results of our faculty as widely and easily available as possible.

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Submissions from 2012

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DJ-1 isoforms in whole blood as potential biomarkers of Parkinson disease, Xiangmin Lin, Travis J. Cook, Cyrus P. Zabetian, James B. Leverenz, Elaine R. Peskind, Shu-Ching Hu, Kevin C. Cain, Catherine Pan, John Scott Edgar, David R. Goodlett, Brad A. Racette, Harvey Checkoway, Thomas J. Montine, Min Shi, and Jing Zhang

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Correlations of coronary plaque wall thickness with wall pressure and wall pressure gradient: A representative case study, Biyue Liu, Jie Zheng, Richard Bach, and Dalin Tang

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CHFR is important for the first wave of ubiquitination at DNA damage sites, Chao Liu, Jiaxue Wu, Sharad C. Paudyal, Zhongsheng You, and Xiaochun Yu

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The C-type natriuretic peptide induces thermal hyperalgesia through a noncanonical Gβγ-dependent modulation of TRPV1 channel, Lipin Loo, Andrew J. Shepherd, Aaron D. Mickle, Ramon A. Lorca, Leonid P. Shutov, Yuriy M. Usachev, and Durga P. Mohapatra

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Splint: The efficacy of orthotic management in rest to prevent equinus in children with cerebral palsy, a randomised controlled trial, Josina C. Maas, Annet J. Dallmeijer, Peter A. Huijing, Janice E. Brunstrom-Hernandez, Petra J. van Kampen, Richard T. Jaspers, and Jules G. Becher

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Common SNPs explain some of the variation in the personality dimensions of neuroticism and extraversion, P. A. F. Madden, A. C. Heath, and et al

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Putative factors that may modulate the effect of exercise on liver fat: Insights from animal studies, Faidon Magkos

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A four-subunit DNA polymerase ζ complex containing Pol δ accessory subunits is essential for PCNA-mediated mutagenesis, Alena V. Makarova, Joseph L. Stodola, and Peter M. Burgers

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Assessing telomeric DNA content in pediatric cancers using whole-genome sequencing data, Elaine R. Mardis, Richard K. Wilson, and et al

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The sodium channel accessory subunit Navβ1 regulates neuronal excitability through modulation of repolarizing voltage-gated K+ channels, Céline Marionneau, Yarimar Carrasquillo, Aaron J. Norris, R. Reid Townsend, Lori L. Isom, Andrew J. Link, and Jeanne M. Nerbonne

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Optimizing read mapping to reference genomes to determine composition and species prevalence in microbial communities, John Martin, Sean Sykes, Sarah Young, Karthik Kota, Ravi Sanka, Nihar Sheth, Joshua Orvis, Erica Sodergren, Zhengyuan Wang, George M. Weinstock, and Makedonka Mitreva

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Optimizing read mapping to reference genomes to determine composition and species prevalence in microbial communities, John Martin, Sean Sykes, Sarah Young, Karthik Kota, Ravi Sanka, Nihar Sheth, Joshua Orvis, Erica Sodergren, Zhengyuan Wang, George M. Weinstock, and Makedonka Mitreva

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Mitochondrial dysfunction and β-cell failure in type 2 diabetes mellitus, Zhongmin Alex Ma, Zhengshan Zhao, and John Turk

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Recognizing and managing the expanded risk of tumor lysis syndrome in hematologic and solid malignancies, Ali McBride and Peter Westervelt

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Structural mechanism of ER retrieval of MHC class I by cowpox, William H. McCoy IV, Xiaoli Wang, Wayne M. Yokoyama, Ted H. Hansen, and Daved H. Fremont

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Vascular anatomy of the tibiofibular syndesmosis, Kathleen E. McKeon, Rick W. Wright, Jeffrey E. Johnson, Jeremy J. McCormick, and Sandra E. Klein

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Lack of short-term effectiveness of rotating treadmill training on turning in people with mild-to-moderate Parkinson's disease and healthy older adults: A randomized, controlled study, Marie E. McNeely and Gammon M. Earhart

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Transcriptomic and proteomic analyses of a Wolbachia- free filarial parasite provide evidence of trans-kingdom horizontal gene transfer, Samantha N. McNulty, Sahar Abubucker, Gabriel M. Simon, Makedonka Mitreva, Nathan P. McNulty, Kerstin Fischer, Kurt C. Curtis, Norbert W. Brattig, Gary J. Weil, and Peter U. Fischer

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Comparing the mitochondrial genomes of Wolbachia-dependent and independent filarial nematode species, Samantha N. McNulty, Andrew S. Mullin, Jefferson A. Vaughan, Vasyl V. Tkach, Gary J. Weil, and Peter U. Fischer

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What would make getting colorectal cancer screening easier? Perspectives from screeners and nonscreeners, Gilda G. Medina, Amy McQueen, Anthony J. Greisinger, L. Kay Bartholomew, and Sally W. Vernon

Progression from sustained BK viruria to sustained BK viremia with immunosuppression reduction is not associated with changes in the noncoding control region of the BK virus genome, Imran A. Memon, Bijal A. Parikh, Monique Gaudreault-Keener, Rebecca Skelton, Gregory A. Storch, and Daniel C. Brennan

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Progression from sustained BK viruria to sustained BK viremia with immunosuppression reduction is not associated with changes in the noncoding control region of the BK virus genome, Imran A. Memon, Bijal A. Parikh, Monique Gaudreault-Keener, Rebecca Skelton, Gregory A. Storch, and Daniel C. Brennan

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An analysis of the transcriptome of Teladorsagia circumcincta: Its biological and biotechnological implications, Ranjeeta Menon, Robin B. Gasser, Makedonka Mitreva, and Shoba Ranganathan

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An institutional perspective on the impact of recent antibiotic exposure on length of stay and hospital costs for patients with gram-negative sepsis, Scott Micek, Michael T. Johnson, Richard Reichley, and Marin H. Kollef

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Evidence of differential allelic effects between adolescents and adults for plasma high-density lipoprotein, Rita PS Middelberg, Andrew C. Heath, Pamela AF Madden, Grant W. Montgomery, Nicholas G. Martin, and John B. Whitfield

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Deciphering a global network of functionally associated post-translational modifications, Pablo Minguez, Luca Parca, Francesca Diella, Daniel R. Mende, Runjun Kumar, Manuela Helmer-Citterich, Anne-Claude Gavin, Vera van Noort, and Peer Bork

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Development of a new humanized mouse model to study acute inflammatory arthritis, Alexander V. Misharin, G K. Haines, Shawn Rose, Angelical K. Gierut, Richard S. Hotchkiss, and Harris Perlman

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Mitofusin2 mutations disrupt axonal mitochondrial positioning and promote axon degeneration, Albert L. Misko, Yo Sasaki, Elizabeth Tuck, Jeffrey Milbrandt, and Robert H. Baloh

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Association between human papillomavirus DNA and temporal arteritis, Amir Mohammadi, John D. Pfeifer, and James S. Lewis

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Ligand-induced movements of inner transmembrane helices of Glut1 revealed by chemical cross-linking of di-cysteine mutants, Mike Mueckler and Carol Makepeace

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Neural synchrony during response production and inhibition, Victor Muller and Andrey P. Anokhin

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Neural synchrony during response production and inhibition, Viktor Muller and Andrey P. Anokhin

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Neural synchrony during response production and inhibition, Viktor Muller and Andrey P. Anokhin

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Relationships between serum MCP-1 and subclinical kidney disease: African American-Diabetes Heart Study, Mariana Murea, Thomas C. Register, Jasmin Divers, Donald W. Bowden, J. Jeffrey Carr, Caresse R. Hightower, Jianzhao Xu, S. Carrie Smith, Keith A. Hruska, Carl D. Langefeld, and Barry I. Freedman

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Frequent hospital readmissions for Clostridium difficile infection and the impact on estimates of hospital-associated C. difficile burden, Courtney R. Murphy, Taliser R. Avery, Erik R. Dubberke, and Susan S. Huang

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Periacetabular osteotomy and combined femoral head-neck junction osteochondroplasty: A minimum two-year follow-up cohort study, Nader A. Nassif, Perry L. Schoenecker, Robert Thorsness, and John C. Clohisy

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Meniscal Repair outcomes at greater than five years: A systematic literature review and meta-analysis, Jeffrey J. Nepple, Warren R. Dunn, and Rick W. Wright

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Description of a multicenter safety checklist for intraoperative hemorrhage control while clamped during robotic partial nephrectomy, Kenneth G. Nepple, Gurdarshan S. Sandhu, Craig G. Rogers, Mohamad E. Allaf, Jihad H. Kaouk, Robert S. Figenshau, Michael D. Stifelman, and Sam B. Bhayani

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Reliability and validity of the Wolfram Unified Rating Scale (WURS), Chau Nguyen, Erin R. Foster, Alexander R. Paciorkowski, Amy Viehoever, Colleen Considine, Aidena Bondurant, Bess A. Marshall, Tamara Hershey, and Washington University Wolfram Study Group

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Hospitalized cardiovascular events in patients with diabetic macular edema, Bao-Anh Nguyen-Khoa, Earl L. Goehring Jr., Winifred Werther, Anne E. Fung, Diana V. Do, Rajendra S. Apte, and Judith K. Jones

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A bioinformatics filtering strategy for identifying radiation response biomarker candidates, Jung Hun Oh, Harry P. Wong, Xiaowei Wang, and Joseph O. Deasy

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Incorporating patient preference into the management of infertility in women with polycystic ovary syndrome, Ugochi C. Okoroafor and Emily S. Jungheim

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Cancer immunoediting by the innate immune system in the absence of adaptive immunity, Timothy O'Sullivan, Robert Saddawi-Konefka, William Vermi, Catherine M. Koebel, Cora Arthur, J. Michael White, Ravi Uppaluri, Daniel M. Andrews, Shin Foong Ngiow, Michele W. L. Teng, Mark J. Smith, Robert D. Schreiber, and Jack D. Bui

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Constitutively active canonical NF-kappaB pathway induces severe bone loss in mice, Jesse E. Otero, Tim Chen, Kaihua Zhang, and Yousef Abu-Amer

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Constitutively active canonical NF-kB pathway induces severe bone loss in mice, Jesse E. Otero, Tim Chen, Kaihua Zhang, and Yousef Abu-Amer

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High throughput screening for small molecule enhancers of the interferon signaling pathway to drive next-generation antiviral drug discovery, Dhara A. Patel, Anand C. Patel, William C. Nolan, Yong Zhang, and Michael J. Holtzman

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Multi-Institutional experience with FOLFIRINOX in pancreatic adenocarcinoma, Parvin F. Peddi, Sam Lubner, Robert McWilliams, Benjamin R. Tan, Joel Picus, Steven M. Sorscher, Rama Suresh, A Craig Lockhart, Jian Wang, Christine Menias, Feng Gao, David Linehan, and Andrea Wang-Gilliam

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The trauma patient in hemorrhagic shock: How is the C-priority addressed between emergency and ICU admission?, Sigune Peiniger, Thomas Paffrath, Manuel Mutschler, Thomas Brockamp, Matthew Borgmann, Philip C. Spinella, Bertil Bouillon, Marc Maegele, and TraumaRegister DGU

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Multi-locus genome-wide association analysis supports the role of glutamatergic synaptic transmission in the etiology of major depressive disorder, M. L. Pergadia and et al

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Whole genome sequence of Treponema pallidum ssp. pallidum, strain Mexico A, suggests recombination between yaws and syphilis strains, Helena Petrosova, Maria Zobanikova, Darina Cejkova, Lenka Mikalova, Petra Pospisilova, Michal Strouhal, Lei Chen, Xiang Qin, Donna M. Muzny, George M. Weinstock, and David Smajs

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The Vermont oxford neonatal encephalopathy registry: Rationale, methods, and initial results, Roger H. Pfister, Peter Bingham, Erika M. Edwards, Jeffrey D. Horbar, Michael J. Kenny, Terrie Inder, Karin B. Nelson, Tonse Raju, and Roger F. Soll

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Early presentation of gait impairment in Wolfram Syndrome, Kristen A. Pickett, Ryan P. Duncan, James Hoekel, Bess Marshall, Tamara Hershey, Gammon M. Earhart, and Washington University Wolfram Study Group

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A cross-species analysis of microRNAs in the developing avian face, Kara E. Powder, Yuan-Chieh Ku, Samantha A. Brugmann, Rose A. Veile, Nicole A. Renaud, Jill A. Helms, and Michael Lovett

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Cost-effectiveness of peer-delivered interventions for cocaine and alcohol abuse among women: A randomized controlled trial, Jennifer Prah Ruger, Arbi Ben Abdallah, Craig Luekens, and Linda Cottler

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Advancing the application, quality and harmonization of implementation science measures, Borsika A. Rabin, Peyton Purcell, Sana Naveed, Richard P. Moser, Michelle D. Henton, Enola K. Proctor, Ross C. Brownson, and Russell E. Glasgow

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Population-based rare variant detection via pooled exome or custom hybridization capture with or without individual indexing, Enrique Ramos, Benjamin T. Levinson, Sara Chasnoff, Andrew Hughes, Andrew L. Young, Katherine Thornton, Allie Li, Francesco L.M Vallania, Michael Province, and Todd E. Druley

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Effects of Doxycycline on gene expression in Wolbachia and Brugia malayi adult female worms in vivo, Ramakrishna U. Rao, Yuefang Huang, Sahar Abubucker, Michael Heinz, Seth D. Crosby, Makedonka Mitreva, and Gary J. Weil

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CXCL12 mediates trophic interactions between endothelial and tumor cells in glioblastoma, Shyam Rao, Rajarshi Sengupta, Eun Joo Choe, B. Mark Woerner, Erin Jackson, Tao Sun, Jeffrey Leonard, David Piwnica-Worms, and Joshua B. Rubin

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Neural correlates of prior expectations of motion in the lateral intraparietal and middle temporal areas, Vinod Rao, Gregory C. DeAngelis, and Lawrence H. Snyder

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LINC complexes mediate the positioning of cone photoreceptor nuclei in mouse retina, David Razafsky, Nathaniel Blecher, Alexander Markov, P. J. Stewart-Hutchinson, and Didier Hodzic

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Health related quality of life outcomes for unresectable stage III or IV melanoma patients receiving ipilimumab treatment, Dennis A. Revicki, Alfons JM van den Eertwegh, Paul Lorigan, Celeste Lebbe, Gerald Linette, Christian H. Ottensmeier, Shima Safikhani, Marianne Messina, Alex Hoos, Samuel Wagner, and Srividya Kotapati

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IS-seq: A novel high throughput survey of in vivo IS6110 transposition in multiple Mycobacterium tuberculosis genomes, Alejandro Reyes, Andrea Sandoval, Andrés Cubillos-Ruiz, Katherine E. Varley, Ivan Hernández-Neuta, Sofía Samper, Carlos Martín, María Jesús García, Viviana Ritacco, Lucelly López, Jaime Robledo, María Mercedes Zambrano, Robi D. Mitra, and Patricia Del Portillo

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Expression of sialic acids and other nonulosonic acids in Leptospira, Jessica N. Ricaldi, Michael A. Matthias, Joseph M. Vinetz, and Amanda L. Lewis

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Functional relationships between lipid metabolism and liver regeneration, David A. Rudnick and Nicholas O. Davidson

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Hepatitis C virus mediated changes in miRNA-449a modulates inflammatory biomarker YKL40 through components of the NOTCH signaling pathway, Nayan J. Sarma, Venkataswarup Tiriveedhi, Vijay Subramanian, Surendra Shenoy, Jeffrey S. Crippin, William C. Chapman, and Thalachallour Mohanakumar

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CIN85 phosphorylation is essential for EGFR ubiquitination and sorting into multivesicular bodies, Barbara Schroeder, Subhashini Srivatsan, Andrey Shaw, Daniel Billadeau, and Mark A. McNiven

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Mechanisms of remodeling in asthmatic airways, Adrian Shifren, Chad Witt, Chandrika Christie, and Mario Castro

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Zebrafish neurofibromatosis type 1 genes have redundant functions in tumorigenesis and embryonic development, Jimann Shin, Arun Padmanabhan, Eric D. de Groh, Jeong-Soo Lee, Sam Haidar, Suzanne Dahlberg, Feng Guo, Shuning He, Marc A. Wolman, Michael Granato, Nathan D. Lawson, Scot A. Wolfe, Seok-Hyung Kim, Lilianna Solnica-Krezel, John P. Kanki, Keith L. Ligon, Jonathan A. Epstein, and A. Thomas Look

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Thalamocortical dysfunction and thalamic injury after asphyxial cardiac arrest in developing rats, Michael Shoykhet, Daniel J. Simons, Henry Alexander, Christina Hosler, Patrick M. Kochanek, and Robert S. Clark

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A tetravalent dengue nanoparticle stimulates antibody production in mice, Elisangela F. Silva, Mariana Orsi, Angela L. Andrade, Rosana Z. Domingues, Breno M. Silva, Helena RC de Araujo, Paulo FP Pimenta, Michael S. Diamond, Eliseu SO Rocha, Erna G. Kroon, Luiz CC Malaquias, and Luiz FL Coelho

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Sexually dimorphic effect of aging on skeletal muscle protein synthesis, Gordon I. Smith, Dominic N. Reeds, Angela M. Hall, Kari T. Chambers, Brian N. Finck, and Bettina Mittendorfer

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Upper extremity-specific measures of disability and outcomes in orthopaedic surgery, Matthew V. Smith, Ryan P. Calfee, Keith M. Baumgarten, Robert H. Brophy, and Rick W. Wright

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Lower extremity-specific measures of disability and outcomes in orthopaedic surgery, Matthew V. Smith, Sandra E. Klein, John C. Clohisy, Geneva R. Baca, Robert H. Brophy, and Rick W. Wright

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Complete genome sequence of Enterococcus faecium strain TX16 and comparative genomic analysis of Enterococcus faecium genomes, Erica Sodergren, George M. Weinstock, and et al

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Complement regulatory protein Crry deficiency contributes to the antigen specific recall response in experimental autoimmune myasthenia gravis, Jindrich Soltys and Xiaobo Wu

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Spontaneous activity promotes synapse formation in a cell-type-dependent manner in the developing retina, Florentina Soto, Xiaofeng Ma, Jacob L. Cecil, Bradly Q. Vo, Susan M. Culican, and Daniel Kerschensteiner

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Measurement properties of a novel survey to assess stages of organizational readiness for evidence-based interventions in community chronic disease prevention settings, Katherine A. Stamatakis, Amy McQueen, Carl Filler, Elizabeth Boland, Mariah Dreisinger, Ross C. Brownson, and Douglas A. Luke

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CCL2 upregulation triggers hypoxic preconditioning-induced protection from stroke, Ann M. Stowe, Bradley K. Wacker, Petra D. Cravens, Jennifer L. Perfater, Min K. Li, Ruilong Hu, Angela B. Freie, Olaf Stuve, and Jeffrey M. Gidday

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Genome-wide meta-analyses of smoking behaviors in African Americans, Y. J. Sung, D. C. Rao, and et al

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Why does Jack, and not Jill, break his crown? Sex disparity in brain tumors, Tao Sun, Nicole M. Warrington, and Joshua B. Rubin

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Trichomonosis, a common curable STI, and prostate carcinogenesis—a proposed molecular mechanism, Siobhan Sutcliffe, Calvin Neace, Nancy S. Magnuson, Raymond Reeves, and J F. Alderete

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Trichomonosis, a common curable STI, and prostate carcinogenesis—A proposed molecular mechanism, Siobhan Sutcliffe, Calvin Neace, Nancy S. Magnuson, Raymond Reeves, and J. F. Alderete

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The Legionella IcmSW complex directly interacts with DotL to mediate translocation of adaptor-dependent substrates, Molly C. Sutherland, Thuy Linh Nguyen, Victor Tseng, and Joseph P. Vogel

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2'-O methylation of the viral mRNA cap by West Nile virus evades Ifit1-dependent and -independent mechanisms of host restriction in vivo, Kristy J. Szretter, Brian P. Daniels, Hyelim Cho, Maria D. Gainey, Wayne M. Yokoyama, Michael Gale Jr., Herbert W. Virgin, Robyn S. Klein, Ganes C. Sen, and Michael S. Diamond

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The use of live attenuated influenza vaccine (LAIV) in healthcare personnel (HCP): Guidance from the society for healthcare epidemiology of America (SHEA), Thomas R. Talbot, Hilary Babcock, Deborah Cotton, Lisa L. Maragakis, Gregory A. Poland, Edward J. Septimus, Michael L. Tapper, and David J. Weber

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Measuring Granger causality between cortical regions from voxelwise fMRI BOLD signals with LASSO, Wei Tang, Steven L. Bressler, Chad M. Sylvester, Gordon L. Shulman, and Maurizio Corbetta

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Increased prevalence of anellovirus in pediatric patients with fever, Erin McElvania TeKippe, Kristine M. Wylie, Elena Deych, Erica Sodergren, George Weingstock, and Gregory A. Storch

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Lack of evidence from studies of soluble protein fragments that Knops blood group polymorphisms in complement receptor-type 1 are driven by malaria, Patience B. Tetteh-Quarcoo, Christoph Q. Schmidt, Wai-Hong Tham, Richard Hauhart, Haydyn D T Mertens, Arthur Rowe, John P. Atkinson, Alan F. Cowman, J Alexandra Rowe, and Paul N. Barlow

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Unraveling the genetic etiology of adult antisocial behavior: A genome-wide association study, Jorim J. Tielbeek, Sarah E. Medland, Beben Benyamin, Enda M. Byrne, Andrew C. Heath, Pamela A. F. Madden, Nicholas G. Martin, Naomi R. Wray, and Karin J. H. Verweij

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The role of molecular chaperonins in warm ischemia and reperfusion injury in the steatotic liver: A proteomic study, Venkataswarup Tiriveedhi, Kendra D. Conzen, Jane Liaw-Conlin, Gundumi Upadhya, James Malone, R. Reid Townsend, Robnet Kerns, Jianluo Jia, Krista Csontos, Sabarinathan Ramachandran, Thallachallour Mohanakumar, Christopher D. Anderson, and William C. Chapman

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Postprandial leucine and insulin responses and toxicological effects of a novel whey protein hydrolysate-based supplement in rats, Ryan G. Toedebusch, Thomas E. Childs, Shari R. Hamilton, Jan R. Crowley, Frank W. Booth, and Michael D. Roberts

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Prospects for a novel ultrashort pulsed laser technology for pathogen inactivation, Shaw-Wei D. Tsen, Tzyy C. Wu, Juliann G. Kiang, and Kong-Thon Tsen

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Functional assessment of human coding mutations affecting skin pigmentation using zebrafish, Zurab R. Tsetskhladze, Victor A. Canfield, Khai C. Ang, Steven M. Wentzel, Katherine P. Reid, Arthur S. Berg, Stephen L. Johnson, Koichi Kawakami, and Keith C. Cheng

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Optimizing global health experiences in emergency medicine residency programs: A consensus statement from the Council of Emergency Medicine Residency Directors 2011 Academic Assembly global health specialty track, Janis P. Tupesis, Christine Babcock, Doug Char, Kumar Alagappan, Braden Hexom, and G. B. Kapur

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Organization of Vomeronasal Sensory Coding Revealed by Fast Volumetric Calcium Imaging, Diwakar Turaga and Timothy E. Holy

Intermuscular adipose tissue is muscle specific and associated with poor functional performance, Lori J. Tuttle, David R. Sinacore, and Michael J. Mueller

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Intermuscular adipose tissue is muscle specific and associated with poor functional performance, Lori J. Tuttle, David R. Sinacore, and Michael J. Mueller

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Physiological notch signaling maintains bone homeostasis via RBPjk and Hey upstream of NFATc1, Xiaolin Tu, Jianquan Chen, Joohyun Lim, Courtney M. Karner, Seung-Yon Lee, Julia Heisig, Cornelia Wiese, Kameswaran Surendran, Raphael Kopan, Manfred Gessler, and Fanxin Long

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A first step in determining appropriate amounts of obstetric anesthesia work, Swarup S. Varaday and Barbara L. Leighton

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Potential implications of HCN channel dysfunction after subarachnoid hemorrhage, Ananth K. Vellimana